A5011747753- Dental Implant Techniques and Outcomes
- Dental Radiography and Imaging
- Traumatic Brain Injury and Neurovascular Disturbances
- Bone Tissue Engineering Materials
- Periodontal Regeneration and Treatments
- Reconstructive Surgery and Microvascular Techniques
- Orthodontics and Dentofacial Orthopedics
- Reconstructive Facial Surgery Techniques
- Cleft Lip and Palate Research
- Esophageal and GI Pathology
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury Research
- Inflammatory Biomarkers in Disease Prognosis
- Urologic and reproductive health conditions
- Bone Metabolism and Diseases
- Genital Health and Disease
- Graphene and Nanomaterials Applications
- Nanoparticle-Based Drug Delivery
- Urological Disorders and Treatments
- MRI in cancer diagnosis
- Craniofacial Disorders and Treatments
- Connective Tissue Growth Factor Research
- Trigeminal Neuralgia and Treatments
- Hydrogels: synthesis, properties, applications
- Intracranial Aneurysms: Treatment and Complications
Qingdao University
2019-2024
Affiliated Hospital of Qingdao University
2019-2024
China Agricultural University
2024
Tianjin Medical University General Hospital
2020-2023
Yuhuangding Hospital
2021-2022
Qingdao Women and Children's Hospital
2022
Suzhou Municipal Hospital
2019-2022
Nanjing Medical University
2022
Zhenjiang City Fourth People's Hospital
2021
Jiangsu University
2021
In clinical practice, challenges remain in the treatment of large infected bone defects. Bone tissue engineering scaffolds with good mechanical properties and antibiotic-controlled release are powerful strategies for infection treatment. this study, we prepared polylactic acid (PLA)/nano-hydroxyapatite (nHA) vertical orthogonal staggered structures by applying 3D printing technology. addition, vancomycin (Van)-based chitosan (CS) hydrogel (Gel@Van) was loaded on scaffold (PLA/nHA/CS-Van) to...
Lung cancer is the leading cause of cancer-related death in world. To explore tumor biomarkers for clinical application, two-dimensional fluorescence difference gel electrophoresis and subsequent MALDI-TOF/TOF mass spectrometry were performed to identify proteins differentially expressed 12 pairs lung squamous cell tumors their corresponding normal tissues. A total 28 nonredundant identified with significant alteration tumors. The up-regulation isocitrate dehydrogenase 1 (IDH1), superoxide...
Abstract Purpose: Effective biomarkers for the diagnosis of non–small cell lung cancer (NSCLC) are needed. We previously showed that isocitrate dehydrogenase 1 (IDH1) is significantly increased in NSCLC tumors. This study aimed to examine plasma levels IDH1 a large patient population evaluate its effectiveness diagnosis. Experimental Design: The IDH1, CA125, Cyfra21-1, and CEA were assayed by ELISA. Blood samples obtained from 1,422 participants (943 patients with 479 healthy controls)....
To evaluate the prognostic value of Lymphovascular Invasion (LVI) in patients with squamous cell carcinoma penis (SCCP) following surgery. This retrospective study analyzed data 891 eligible SCCP who were diagnosed between 2010 and 2014, obtained from Surveillance, Epidemiology, End Results (SEER) database. The categorized by LVI, age, grade, T stage, lymph nodes status, distant metastasis, regional removed, Overall survival (OS) penile carcinoma-specific (PCSS) evaluated Kaplan-Meier method...
Abstract Background The systemic immune-inflammation index (SII) is an emerging prognostic marker of cancer. We aimed to explore the predictive ability SII on acute kidney injury (AKI) and prognosis in patients with spontaneous cerebral hemorrhage (SCH) who underwent craniotomy. Methods Patients SCH craniotomy between 2014 2021 were enrolled this study. epidemiology factors for AKI after analyzed. clinical outcomes further investigated. then analyzed using a logistic regression model...
Herein, we introduce a novel composite hydrogel scaffold designed for addressing infectious jaw defects, significant challenge in clinical settings caused by the inherent limited self-regenerative capacity of bone tissues. The was engineered from blend carboxymethyl chitosan (CMCS)/sodium alginate (SA) (CSH), β-cyclodextrin/chlorhexidine clathrate (β-CD-CHX), and strontium-nanohydroxyapatite nanoparticles (Sr-nHA). β-CD-CHX Sr-nHA components were synthesized using saturated aqueous solution...
The study aimed to explore the osteogenic effect induced by combined use of bone morphogenetic protein-2 (BMP-2), vascular endothelial growth factor (VEGF), and transforming factor-β1 (TGF-β1), attain best combination for quality efficiency, network regulation mechanisms osteogenesis. MC3T3-E1 cells were cultured in vitro, BMP-2, VEGF, TGF β1 added induction mediums different combinations conduct experiments. At 7 14 days, alkaline phosphatase (ALP) Alizarin Red S (ARS) staining applied...
The design and preparation of advanced nanocatalysts for the sensitive electrochemical detection H2O2 is great significance. Herein, a facile Pt@Co/MoN sensing platform was fabricated by depositing Pt nanoparticles onto Co/MoN nanoarrays using atomic layer deposition (ALD) technology. Benefitting from unique nanostructure strong interaction between nitride support, prepared exhibited excellent performance in H2O2. This work provides an interesting strategy to fabricate low-Pt...
Abstract Accurate application of the preoperative surgical plan in actual settings is paramount importance orthognathic surgery. This randomized controlled clinical trial aimed to evaluate accuracy computer-aided intraoperative navigation (Ci-Navi) compared with that conventional methods bimaxillary Fifty-two patients were randomly divided into 2 groups. Group A (n = 26) underwent surgery assisted Ci-Navi and group B methods. During operation, after LeFort I osteotomy, mobile maxilla was...
To examine the accuracy of computer-aided intraoperative navigation (Ci-Navi) in bimaxillary orthognathic surgery by comparing preoperative planning and postoperative outcome.The study comprised 45 patients with congenital dentomaxillofacial deformities who were scheduled to undergo surgery. Virtual was simulated using Mimics software. Intraoperatively, a Le Fort I osteotomy maxilla performed guide plates. After bilateral sagittal split ramus mandible, mobilized distal mandibular segment...
Neurosurgical patients are at an increased risk of deep venous thrombosis (DVT), which, if not properly managed, can lead to pulmonary embolism. This study aimed investigate the accuracy age-adjusted D-dimer thresholds combined with modified Wells score as a predictor for lower extremity DVT diagnosis.We conducted among aged >50 years suspected in neurosurgery intensive care unit between December 2019 and 2020. Receiver operating characteristic curve analysis was performed examine diagnostic...
Background To determine the association between tumor location and both clinicopathological characteristics survival of patients with M0 squamous cell carcinoma penis (SCCP). Methods Data 455 diagnosed SCCP 1975 2018 were collected from Surveillance, Epidemiology, End Results (SEER) database United States National Cancer Institute. The effects on overall (OS) penile carcinoma-specific (PCSS) analyzed using Kaplan–Meier method. Cox proportional hazards regression model was used to impact...
Abstract The good recovery of hip function after THA depends on reconstruction acetabular prosthesis accurately. So we investigated the effect placement joint and analyzed clinical data 432 patients with unilateral retrospectively . were followed-up to evaluate Harris score range motion (ROM). ROM, rate compared between different groups. Comparison showed that 85%∼100% group rotation center horizontal position ratio was higher than >100% group; 80%∼120% vertical >160% 90%∼110%...
Thymidylate synthase (TS) is a prognostic marker in various tumors. However, the results of previous investigations gastric cancer (GC) were controversial. The objective this article to investigate whether TS expression associated with clinical outcome advanced GC receiving capecitabine alone chemotherapy. study reviewed 58 cases patients aged ≥65 years between December 2008 and June 2012. All treated Immunohistochemical staining for protein was performed. relationships clinicopathological...
To examine the association of alcohol consumption with presence and development ultrasound (US)-detected tophi subcutaneous in a Chinese gout population.A total 554 patients who underwent US physical examination most frequently involved joints were included this study. Multivariable analysis was performed to assess associations duration, quantity, type presence, size, number US-detected tophi.Compared non-drinkers, excessive drinkers (>70 gm/week), long-term (≥10 years), spirits had greater...
Abstract Background Sedated gastroscopy is a crucial procedure for patients with upper respiratory infections. SARS-CoV-2-infected are more susceptible to anesthesia-related complications, such as edema, pharyngeal mucosa congestion, laryngospasm, and pulmonary Methods We retrospectively analyzed total of 386 who underwent sedated at the Affiliated Hospital Qingdao University during SARS-CoV-2 infection period. The were divided into three groups based on status: Negative (N), Two-week...