Distributions of the backbone dihedral angles proteins have been studied for over 40 years. While many statistical analyses presented, only a handful probability densities are publicly available use in structure validation and prediction methods. The distributions differ number important ways, which determine their usefulness various purposes. These include: 1) input data size criteria inclusion (resolution, R-factor, etc.); 2) filtering suspect conformations outliers using B-factors or...

Benefiting from the advantages of low cost, light weight and mechanical flexibility, piezoelectric nanogenerators have potential for application in renewable energy harvesting various unexplored sources.

Recent progress in the synthesis of highly stable, eco-friendly, cost-effective transition-metal dichalcogenide (TMDC) quantum dots (QDs) with their broadband absorption spectra and wavelength selectivity features have led to increasing use photodetectors. With solution-based processing, we demonstrate a superlarge (∼0.75 mm2), ultraviolet-visible (UV-vis) (365-633 nm) phototransistor made WS2 QDs-decorated chemical vapor deposited (CVD) graphene as active channel extraordinary stability...

We investigate the shielding effectiveness and complex conductivity of single-walled carbon nanotubes (SWNT) distributed in a polyvinyl alcohol (PVA) matrix THz frequency range. SWNTs are dispersed PVA matrices with varying SWNT content (keeping thickness SWNT/PVA film constant) using slow-drying method, terahertz time-domain spectroscopy (THz-TDS) is performed at room temperature transmission geometry range 0.3-2.1 THz. The transmittance spectra show possible application composites as...

Here we demonstrate novel self-powered photodetection using silver (Ag) nanoparticle-loaded two-dimensional graphitic carbon nitride (g-C3N4) nanosheets triggered by poly-vinylidene fluoride (PVDF)-based flexible piezoelectric nanogenerators. A self-poled PVDF-based nanogenerator has been obtained upon exploiting pristine g-C3N4 as a filler material within the PVDF matrix. The fabricated devices are found to be highly efficient in generating maximum voltage of ∼2.3 V and power ∼110...

While the liquid-liquid phase separation (LLPS) process in proteins has been studied great detail, it not widely explored how associated protein hydration changes during and crucial its role is itself. In this contribution, we experimentally explore alteration of lysozyme LLPS using attenuated total reflection (ATR)-FTIR spectroscopy THz frequency region (1.5-21 THz). Additionally, excipients (l-arginine, sucrose, bovine albumin (BSA), ubiquitin (Ubi)) regulating found that, while sucrose...

Excited-state proton transfer (ESPT) in organic photoacids is a widely studied phenomenon which D-luciferin of special mention, considering the fact that apart from its phenolic OH group, nitrogen atoms at either two thiazole moieties could also participate hydrogen bonding interactions with proton-donating solvent during ESPT. As result, several transient species appear ESPT process. We hereby deploy subpicosecond time-resolved fluorescence upconversion (FLUP) and absorption (TA)...

Thiocyanate (SCN-) is known to be a naive ion abundant in biological fluids, blood, and urine. It also used as biomarker, it can penetrate the brain by crossing blood barrier (BBB) gets into cerebrospinal fluid (CSF) through blood-CSF barrier. Considering its importance human physiology, we examine effect of SCN- ions on three model proteins: ovalbumin (Ova), bovine serum albumin (BSA), lysozyme (Lys). We observe that an elevated level (∼0.5 M) leads otherwise unusual instant fibrilization...

Human serum albumin (HSA) is a soluble protein in our circulatory system, which known to bind variety of drugs and ligands. Since Sudlow's pioneering works on the ligand-binding sites, major effort biophysical/biochemical research has been directed characterize structural, functional, dynamical properties this protein. Structural studies HSA have revealed distinct temperature-induced folded states. Despite knowing about residues important for binding, less understood temperature-dependent...

Human serum albumin (HSA) is known to undergo both reversible and irreversible thermal unfolding refolding, depending upon the experimental conditions (end temperature) at neutral pH. In this report we have used high precision densimetric ultrasonic measurements determine apparent specific volume (φv) compressibility (φk) of HSA different unfolded refolded states two end temperatures, 55 °C 70 °C. The were characterized using dynamic light scattering (DLS), circular dichroism (CD),...

Hydrogen-bonded structure and relaxation dynamics of water entrapped inside reverse micelles (RMs) composed surfactants with different charged head groups: sodium bis(2-ethylhexyl) sulfosuccinate (AOT) (anionic), didodecyldimethylammonium bromide (DDAB) (cationic) Igepal CO-520 (Igepal) (nonionic) in cyclohexane (Cy) have been studied as a function hydration (defined by ). Sub-diffusive slow (sub-ns) has measured the time resolved fluorescence spectroscopy (TRFS) technique using two...

While two-dimensional (2D) layered MoS2 nanosheets have been extensively studied owing to their fascinating optoelectronic properties, less attention has paid the corresponding zero-dimensional nano-crystals. In this contribution, we report efficacy of nanocrystals for size tunable properties optical and photocatalytic applications. We synthesized differently sized (10-70 nm) crystalline, hexagonal 2H-MoS2 nanoparticles (NPs) dispersed in DMF solvent using a simple exfoliation technique....

A photograph of g-C₃N₄ (CN)-based flexible triboelectric nanogenerator and scheme its applicability for power generation.

In this paper, for the first time, we report a detailed study of temperature-dependent solvation dynamics probe fluorophore, coumarin-500, in AOT/isooctane reverse micelles (RMs) with varying degrees hydration (w0) 5, 10, and 20 at four different temperatures, 293, 313, 328, 343 K. The average time constant becomes faster increase w0 values particular temperature. RM fixed value also observed temperature-induced is associated transition bound- to free-type water molecules, corresponding...

In this contribution, we attempt to correlate the change in water dynamics a reverse micellar (RM) core caused by modification of interface mixing an anionic surfactant, sodium bis(2-ethylhexyl) sulfosuccinate (AOT), and nonionic tetraethylene glycol monododecyl ether (Brij-30), at different proportions, its consequent effect on reactivity water, measured monitoring solvolysis reaction benzoyl chloride (BzCl). The dimension RM droplets ratios AOT Brij-30 (XBrij-30) has been using dynamic...

In recent years, the validity of activation energy barrier crossing model at micellar surface brings notable controversy (Sen, P.; Mukherjee, S.; Halder, A.; Bhattacharyya, K. Chem. Phys. Lett. 2004, 385, 357-361. Kumbhakar, M.; Goel, T.; Pal, H. J. B 108, 19246-19254.) in literature. order to check by time-resolved solvation a probe fluorophore, wider range temperature must be considered. At same time, spatial heterogeneity (solubilization) and structural perturbation host micelle should...