- Congenital Heart Disease Studies
- Tracheal and airway disorders
- Aortic Disease and Treatment Approaches
- Congenital Diaphragmatic Hernia Studies
- Esophageal and GI Pathology
- Cardiac Structural Anomalies and Repair
- Coronary Artery Anomalies
- Cardiovascular Issues in Pregnancy
- Cardiac Valve Diseases and Treatments
- Airway Management and Intubation Techniques
- Infective Endocarditis Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Vascular Anomalies and Treatments
- Surgical Simulation and Training
- Anatomy and Medical Technology
- Mechanical Circulatory Support Devices
- Heart Failure Treatment and Management
- Dysphagia Assessment and Management
- Connective tissue disorders research
- Cardiac and Coronary Surgery Techniques
- Cardiovascular Conditions and Treatments
- Foreign Body Medical Cases
- Cardiac Ischemia and Reperfusion
- Vascular anomalies and interventions
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2025
Ospedali Riuniti Umberto I
2022
Ospedali Riuniti di Ancona
2022
Azienda Ospedaliero Universitaria Ospedali Riuniti
2020-2022
Fondazione Toscana Gabriele Monasterio
2012-2021
Centre Chirurgical Marie Lannelongue
2020
Regione Toscana
2018-2019
San Diego Cardiac Center
2017
Scan Foundation
2015
Ospedale Maria Vittoria
2013
Treatment decisions in patients with scimitar syndrome (SS) are often challenging, especially isolated SS who asymptomatic and might be diagnosed accidentally. We queried a large multi-institutional registry of to evaluate the natural history this condition determine efficacy surgical treatment terms survival clinical status. collected data on 485 from 51 institutions; 279 (57%) were treated surgically (STPs) 206 (43%) clinically monitored (CMPs). Median age at last follow-up was 11.6 years...
The incidence of recurrent aortic arch obstruction after Norwood procedure and other types reconstruction in newborns remains high. Biological synthetic materials are used to enlarge the aorta. We report our experience using autologous pericardium reconstruct patients with hypoplastic left heart syndrome, interruption arch.A retrospective analysis 39 consecutively operated evaluated an initial repair was performed. presence (mean gradient ≥ 20 mmHg) its management were noted. mean weight 3.2...
Abstract The routine use of brain natriuretic peptide (BNP) in pediatric cardiac surgery remains controversial. Our aim was to test whether BNP adds information predict risk surgery. In all, 587 children undergoing (median age 6.3 months; 1.2–35.9 months) were prospectively enrolled at a single institution. measured pre-operatively, on every post-operative day the intensive care unit, and before discharge. primary outcome major complications length ventilator stay >15 days. A first...
Abstract Background: The aim of this study is to test the hypothesis whether combined use a cardio-specific biomarker, brain natriuretic peptide (BNP) and marker early renal damage, assay urinary neutrophil gelatinase-associated lipocalin (uNGAL), may improve risk stratification in pediatric cardiac surgery. Methods: We prospectively enrolled 135 children [median age 7 (interquartile range 1–49) months] undergoing surgery for congenital heart disease. All biomarkers were evaluated pre-...
We reviewed the role of posterior aortopexy for left mainstem bronchus compression in infants and children.Eighteen children with respiratory symptoms were enrolled between 2005 2015 surgical decompression bronchus. The managed from diagnosis to follow-up by a dedicated tracheal team. Primary outcomes complete relief or improvement respect preoperative clinical status.The median age was 4 years (0.3-15.4) weight 13.2 kg (3, 1-40). Symptoms indications bronchoscopy included difficult weaning...
Abstract OBJECTIVES Italy has been one of the countries most severely affected by coronavirus disease 2019 (COVID-19). The Italian government was forced to introduce quarantine measures quickly, and all elective health services were stopped or postponed. This emergency dramatically changed management paediatric adult patients with congenital heart disease. We analysed data from 14 cardiac surgery centres during lockdown, focusing on impact pandemic surgical activity, healthcare providers...
<b>Background</b> The cardioplegia is one of the most significant tools used to increase myocardial protection. aim our study compare use Custodiol solution versus intermitted blood in a retrospective analysis data for patients who underwent arterial switch operation institution. <b>Material and Methods</b> From January 2008 March 2011, protection was performed 44 neonates (blood group) with intermittent cardioplegia. 2011 November 2014, 50 (Custodiol one-shot anterograde <b>Results</b>...
Advances in both imaging techniques and genetics have led to the recognition of a wide variety aortic anomalies that can be grouped under term ‘hereditary thoracic diseases’. The present review aims summarize this very heterogeneous population’s clinical, genetic, characteristics discuss implications diagnosis for clinical counselling (on sports activity or pregnancy), medical therapies surgical management.
Abstract: Congenital tracheal stenosis (CTS) is rare lesions frequently associated with pulmonary sling (PS). Despite the recent improvement in results by introduction of slide tracheoplasty (ST) and multidisciplinary approach, surgical management remains difficult several authors, for this reason, debate a conservative approach these cases. Preoperative planning, require hence use most innovative technology to gain best possible result. This report describes complicated, unsuccessful...
Objective Mitral valve replacement (MVR) is a surgical option when mitral valvuloplasty not feasible/successful. This study reviews our experience with MVR in very young children. Methods From July 2004 to January 2014, seven children (mean age 13.3 ± 11.2 months; range 4 months 35 mean body weight 6.0 2.2 kg) underwent mechanical prosthesis the supra-annular position. To provide better exposure left atrium, we performed all but one case biatrial transeptal incision according Guiraudon. Six...
Despite the fact that team management has improved results in recent years, perioperative deaths and complications remain high paediatric tracheal surgery. We reviewed our institutional experience by comparing with those literature.Between 2005 2017, 30 children underwent surgery for disease. Fifteen were boys fifteen girls (50% vs 50%). The median age at operation was 7 months (15 days-9.6 years), weight 5.2 kg (2.8-34 kg). Congenital stenosis diagnosed 25 (83.3%), 5 (16.7%) had acquired...
OBJECTIVES: Surgery for vascular anomalies can occasionally fail to relieve symptoms, especially when severe tracheobronchial malacia persists. We studied outcomes in children who underwent airway stenting post-surgical and tested known clinical surgical prognostic factors. METHODS: Among 257 evaluated compression, we reviewed the charts 59 patients (23%) surgery. After surgery, whom respiratory symptoms persisted stenting. RESULTS: (boys: 58.1%, median age: 6.4 months, age range: 0.1–182.8...
Big pulmonary artery-left atrial fistula malformation (PALAF) was diagnosed in a 5-year-old boy. Although transcatheter therapy would be preferred as treatment of PALAF, the lesion, which 20 mm diameter and almost totally shunting right main artery, it decided to treat by surgical approach.
Preoperative aortopulmonary mismatch is considered a risk factor for the development of aortic insufficiency after surgery transposition great arteries. We have approached these children using neoaortic root reduction plasty. Five with severe PA–AO discrepancy (median age 57 days) underwent arterial switch operation (ASO) associated V-shape At follow-up regurgitation remains stable in all patients and no supra-aortic obstruction and/or dilatation were observed. doi: 10.1111/jocs.12306 (J...
Low-weight premature neonates (LWPNs) frequently have haemodynamically significant patent ductus arteriosus (PDA) responsible for serious complications. Cyclooxygenase inhibitors are used ductal closure. If the medical treatment fails, PDA can be legated surgically. We present our experience, since 2006, on surgical closure.Material and methods. From 2006 to 2009, of 518 LWPNs, was in 109 (21%) infants. The mean gestational age 29.1 weeks. All patients underwent a Because failure treatment,...
Congenital tracheal stenosis is frequently associated with heart malformations. Simultaneous correction of both anomalies has been advocated by several authors. We describe our experience a premature neonate congenital and tetralogy Fallot. The were corrected during the same surgical procedure aid extracorporeal circulation. implications operative postoperative courses, concerning cardiac anomaly are discussed.
Left pulmonary artery (LPA) sling (PAS) is a vascular ring, which frequently associated with long-segment tracheal stenosis (TS). Mortality rate in operated children still high, especially cases of severe hypoplasia and/or congenital heart defects (CHDs). We report our experience treatment and follow-up pediatric cohort patients affected by PAS tracheobronchial involvement.From 2005 to 2017, we enrolled 11 diagnosed TS requiring surgical intervention. Echocardiography, computed tomography,...