In recent years, the rapid development of mobile medical technology has provided multiple ways for long-term management chronic diseases, especially diabetes. As a new type model, smartphone apps are global, convenient, cheap, and interactive. Although were proved to be more effective at glycemic control, compared with traditional computer- Web-based telemedicine technologies, how gain further sustained improvement is still being explored.

An up-to-date comprehensive assessment of the cancer burden attributable to risk factors is essential for prevention. We analyzed population fraction (PAF) disability-adjusted life years (DALYs) 11 level 2 using data from Global Burden and Disease Study (GBD) 2019. highlighted that almost half DALYs can be preventable by modifying relevant factors. The increased 60.42%-105.0 million 1990 Tobacco, dietary risks, alcohol use, high body-mass index, air pollution were top five PAFs fasting...

The aim of this study was to investigate the interrelationships between three bone-derived factors [serum osteocalcin (OCN), fibroblast growth factor (FGF) 23, and neutrophil gelatinase-associated lipocalin (NGAL) levels] body fat content distribution, in order reveal potential endocrine function bone development obesity. We recruited 1179 people (aged 59.5 ± 6.2 years) from communities Shanghai. Serum OCN levels were determined using an electrochemiluminescence immunoassay. FGF23 NGAL a...

Abstract Serum 1,5-anhydroglucitol (1,5-AG) levels can not only accurately reflect the mean blood glucose over previous 1–2 weeks in diabetic patients but also offers advantage of representing postprandial glucose. To evaluate clinical significance 1,5-AG diabetes detection, especially when used combination with fasting plasma (FPG), a total 3098 participants at high risk for (1467 men, 1631 women) were enrolled. A 1471 (47.5%) diagnosed diabetes, and level group was significantly lower than...

Summary Recent studies have shown that circulating fibroblast growth factor ( FGF ) 23 and vitamin D levels are closely correlated with insulin resistance. The aim of this study was to investigate the relationship among serum levels, 25‐hydroxyvitamin [25( OH )D] non‐alcoholic fatty liver disease NAFLD in Chinese patients type 2 diabetes mellitus (T2 DM ). This enrolled 331 hospitalized T2 (209 122 without Serum were measured using a sandwich enzyme‐linked immunosorbent assay. 25( )D...

Abstract Background Clinical and basic investigations have indicated a significant association between circulating growth differentiation factor 15 (GDF15) cardiovascular disease; however, the relationship GDF15 lower extremity atherosclerotic disease (LEAD) has been less studied. The present study aimed to explore LEAD in Chinese patients with type 2 diabetes mellitus (T2DM). Considering that obesity is an important associated levels, whether serum levels affected by body mass index (BMI)...

Recently, basic and clinical studies have provided evidence supporting the relationship between circulating levels of fibroblast growth factor (FGF) 23 development atherosclerosis. Given that diabetes is an established risk for lower extremity atherosclerotic disease (LEAD), goal present study was to explore serum FGF23 LEAD, as well related factors, in Chinese patients with type 2 mellitus (T2DM). A total 401 hospitalized T2DM (201 subjects LEAD 200 without LEAD) were enrolled this study....

Abstract Background & Aims Serum adipocyte fatty acid‐binding protein (A‐FABP) is closely correlated to metabolic disorders such as obesity and insulin resistance ( IR ). Non‐alcoholic liver disease NAFLD ) a typical feature of in the liver. The aim this study was explore relationship between serum A‐ FABP levels . Methods enrolled 728 subjects with normal glucose tolerance from communities. A‐FABP were measured using sandwich enzyme‐linked immunosorbent assay. fat content assessed by...

The rate of glycemic control among diabetes patients in China is currently low. current study aims at determining the effect structured self-monitoring blood glucose (SMBG) on as well quality life (QoL) Chinese patients.In a 24-week, single-center, randomized, open-label, prospective trial, with glycated hemoglobin A1c (HbA1c) >8.0% were randomized to an intervention group for SMBG (n = 121) or 129). Patient data analyzed separately according treatment without insulin. At 0, 3rd, and 6th...

Abstract Aim This study aimed to investigate alterations in HbA 1c , glycated albumin ( GA ) and 1,5‐anhydroglucitol (1,5‐ AG Chinese first‐degree relatives of individuals with diabetes FDR pursuit an index for early screening glucose metabolism disturbance. Methods A total 467 participants (age range: 20–78 years) normal weight tolerance, as determined by a 75‐g oral tolerance test, were enrolled. was measured using high‐performance liquid chromatography. Serum 1,5‐ levels enzymatic...

Background . Our previous study indicated that serum 1,5-anhydroglucitol (1,5-AG) levels slightly increased after a glucose load; therefore, this was conducted to explore short-term changes in 1,5-AG steamed bread meal test (SBMT) and compare the agreement of 1,5-AG, glycated albumin (GA), hemoglobin A1c (HbA1c) between fasting postprandial states an SBMT. Methods 104 participants were recruited underwent 100 g Fasting, 30 min, 120 min GA, HbA1c measured. Results Levels from SBMT (<mml:math...

Objective: To explore the normal values for two-dimension solid state high resolution anorectal manometry (HRAM) in healthy adult volunteers. Methods: The volunteers were recruited by advertisement and underwent HRAM left lateral position. Anorectal pressures rectal sensation recorded analyzed. Results: (1) A total of 126 Chinese (male: 50 cases (39.7%); age: (37.5±14.2) years old ) this study. (2) Mean anal resting pressure (MERP) was (71.8±17.3) mmHg (1 mmHg=0.133 kPa). Maximum (MARP)...

In previous epidemiological screening in China, glycated albumin (GA) was mostly detected during the fasting state. This strict restriction causes some problems with diabetes screening. It is unclear if GA could help improve efficiency of for subjects who are not The present study analyzed differences between and postload (30, 60, 120, 180 min) levels. A total 691 participants were enrolled study. Bland-Altman difference plots revealed that 95.4, 94.8, 93.6, 93.9% data points within limits...

The integrated curriculum was recently introduced to the foundation medical education in Chinese schools. In this context, Wuhan University has offered two courses, ie., Cell, Molecule and Genes (CMG) Tissue Function (TF). purpose of paper is unfold problems design implementation curricula by analyzing these courses explore possible ways improve them. A Likert questionnaire survey conducted on 102 second year students at understand their experiences various aspects curriculum. result showed...

How to improve the level of students' professional knowledge integration is a systematic project, especially after construction goal new business discipline put forward, it very significant challenge teaching discipline. Based on research background comprehensive and disciplinary competitions such as Internet+ innovation entrepreneurship, participating student teams object, this paper points out that there are problems insufficient cognition value promoting learning by competition, sources...