- Pelvic floor disorders treatments
- Maternal and Perinatal Health Interventions
- Pelvic and Acetabular Injuries
- Pregnancy-related medical research
- Anorectal Disease Treatments and Outcomes
- Cervical Cancer and HPV Research
- Hernia repair and management
- Maternal and fetal healthcare
- Assisted Reproductive Technology and Twin Pregnancy
- Ovarian cancer diagnosis and treatment
- Health, Medicine and Society
- Urinary Bladder and Prostate Research
- Uterine Myomas and Treatments
- Ureteral procedures and complications
- Gynecological conditions and treatments
- Neonatal Respiratory Health Research
- Neonatal and fetal brain pathology
- Endometrial and Cervical Cancer Treatments
- Urological Disorders and Treatments
- Endometriosis Research and Treatment
- Genital Health and Disease
- Appendicitis Diagnosis and Management
- Sarcoma Diagnosis and Treatment
- Ectopic Pregnancy Diagnosis and Management
- Enhanced Recovery After Surgery
Université de franche-comté
2016-2025
Centre Hospitalier Universitaire de Besançon
2016-2025
Inserm
2017-2025
Université Bourgogne Franche-Comté
2021
Franche-Comté Électronique Mécanique Thermique et Optique - Sciences et Technologies
2021
Centre National de la Recherche Scientifique
2021
Université Paris Cité
2020
Hôpital Bichat-Claude-Bernard
2020
Hôpital Femme Mère Enfant
2013-2017
Hôpital Saint-Jacques
2005-2014
Problem To evaluate the inflammatory pattern in maternal circulation from women with preterm premature rupture of membranes ( PPROM ) considering occurrence histologically confirmed chorioamnionitis HCA ). Method study A prospective was conducted 121 between 24 and 34 + 0 weeks gestation. Association white blood cells WBC count, plasma CRP , IL ‐6, MCP ‐1 IP ‐10 levels, assessed. Results The rate 44.7% (54/121). During 5 days preceding delivery, median ‐6 levels were significantly higher...
Abstract Introduction Data concerning the mechanical properties of perineum during delivery are very limited. In vivo experiments raise ethical issues. The aim study was to describe some biomechanical each perineal tissue layer collected from sows in order better understand tears childbirth. Material and methods Samples were obtained skin, vagina, external anal sphincter (EAS), internal (IAS), mucosa fresh dead sows. They tested quasi‐static uniaxial tension using testing machine Mach‐1®....
Highlights•Pregnant women are increasingly concerned about childbirth and, in particular, perineal injuries, their prevention and treatment. They have access to health information on the web social networks.•The quality of obstetric tears YouTube was fair this study.•We identified top four videos Youtube were excellent talk tears.•YouTube should be improved better explain public.AbstractObjectiveThe aim study assess reliability tears.MethodWe chose six keywords: "tearing birth", "perineal...
The aim was to study the predictive value and feasibility of fetal scalp lactate microsampling in management non-reassuring status during labor.A prospective observational conducted on cord blood gas samplings from 7,617 singleton cephalic deliveries at > or =37 weeks gestation. In this population, 450 samples (FBS) were performed for abnormal heart rate (FHR) patterns. Microvolume measurements compared pH, neonatal parameters (pH, lactate, base deficit) Apgar score.Scalp correlated...
Aims The levator ani muscle (LA) injury associated with vaginal birth occurs in a characteristic site of on the inner surface pubic bone to pubovisceral portion muscle's origin. This study investigated gross and microscopic anatomy origin LA this region. Methods Pubic was examined situ then harvested from nine female cadavers (35–98 years). A combination targeted feature sampling sequential used where each specimen cut sequentially approximately 5 mm thick slices apart area known injury....
High-risk HPV (hrHPV) testing has been implemented as a primary screening tool for cervical cancer in numerous countries. However, there is still need relevant triage strategies to manage hrHPV positive women avoid excessive referral colposcopy. The objective of this study was assess, infected by and presenting no or mild cytological abnormalities, HPV16 HPV18 viral loads predict the development high-grade lesion. Among 2102 hrHPV, 885 had lesion abnormalities at baseline least one follow-up...
To describe the trends in rate, treatment, and survival of late-stage vulvar carcinomas (LSVCs) over a 20-year period United States.Demographic, pathologic, data were collected from Surveillance, Epidemiology, End Results registry between 1988 2007. Trends concerning rate LSVC (International Federation Gynecology Obstetrics [FIGO] stages III IV), its management, outcome studied. Five-year overall disease-specific rates calculated.The (32.4%) as compared with early-stage disease (67.6%) did...
Abstract Aims The origin of the pubovisceral muscle (PVM) from pubic bone is known to be at elevated risk for injury during difficult vaginal births. We examined anatomy and histology its enthesial classify type see if it differs appendicular entheses. Methods Parasagittal sections bone, PVM enthesis, myotendinous junction, proper were harvested five female cadavers (51–98 years). Histological prepared with hematoxylin eosin, Masson's trichrome, Verhoeff‐Van Gieson stains. enthesis was...
ABSTRACT High-risk (HR) human papillomavirus (HPV)-associated carcinogenesis is driven mainly by the overexpression of E7 and E6 oncoproteins following viral DNA integration concomitant loss E2 open reading frame (ORF). However, HR-HPV not systematically observed in cervical cancers. The protein acts as a transcription factor that governs oncogene expression. methylation CpGs E2-binding sites (E2BSs) long control region abrogates binding, thus impairing E2-mediated regulation E7/E6...
Adenoid cystic carcinoma of Bartholin's gland is a very rare disease.A 48-year-old premenopausal woman Caucasian origin was delivered adjuvant pelvic and inguinal radiotherapy after prior complete left tumor excision lymph node dissection for adenoid with one metastatic node.Two years primary treatment, she presented to the Emergency Room acute headache, hypoacousia, decrease in visual acuity, right leg muscle strength. A cranial magnetic resonance imaging scan demonstrated three brain...
Objective To assess the incidence of serious complications and reoperations for recurrence after surgery pelvic organ prolapse (POP) compare three most common types repair. Design Prospective cohort study using a registry. Setting Nineteen French surgical centres. Population A total 2309 women participated between 2017 2019. Methods multivariate analysis including an inverse probability treatment weighting approach was used to obtain comparable groups. Main outcome measures Serious...
Abstract Clinical value of pelvimetry in modern obstetrics practices has never been established and normal values are set since the middle twentieth century. The aim this study was to describe current dimensions pelvis a female French Caucasian population. A retrospective, bi-centric observational conducted from August 2013 2019 two departments Obstetrics. We included all women who had computed tomography during pregnancy. primary outcome obstetric transverse diameter, conjugate diameter...