Martin Koskas

ORCID: 0000-0003-3872-2810
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About
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Research Areas
  • Endometrial and Cervical Cancer Treatments
  • Ovarian cancer diagnosis and treatment
  • Uterine Myomas and Treatments
  • Endometriosis Research and Treatment
  • Gynecological conditions and treatments
  • Cervical Cancer and HPV Research
  • Intraperitoneal and Appendiceal Malignancies
  • Ovarian function and disorders
  • Pelvic floor disorders treatments
  • Reproductive Biology and Fertility
  • Clinical practice guidelines implementation
  • Colorectal and Anal Carcinomas
  • Anorectal Disease Treatments and Outcomes
  • Multiple and Secondary Primary Cancers
  • Gastric Cancer Management and Outcomes
  • Cancer Risks and Factors
  • Sarcoma Diagnosis and Treatment
  • Appendicitis Diagnosis and Management
  • Ectopic Pregnancy Diagnosis and Management
  • Estrogen and related hormone effects
  • Reproductive System and Pregnancy
  • Maternal and fetal healthcare
  • Reproductive Health and Contraception
  • Pregnancy-related medical research
  • Management of metastatic bone disease

Assistance Publique – Hôpitaux de Paris
2015-2025

Université Paris Cité
2015-2025

Hôpital Bichat-Claude-Bernard
2016-2025

Sorbonne Paris Cité
2014-2025

Délégation Paris 7
2012-2024

Université Claude Bernard Lyon 1
2014-2024

Evaluation et recherche en services et politiques en santé pour les populations vulnérables
2024

Hôpital Beaujon
2024

Hôpital Fernand-Widal
2023

Hôpital Lariboisière
2023

Endometrial cancer is the most common gynecological malignancy in high-income countries. Although overall prognosis relatively good, high-grade endometrial cancers have a tendency to recur. Recurrence needs be prevented since for recurrent dismal. Treatment tailored tumor biology optimal strategy balance treatment efficacy against toxicity. Standard consists of hysterectomy and bilateral salpingo-oophorectomy. Lymphadenectomy (with ongoing studies sentinel node biopsy) enables identification...

10.1002/ijgo.12612 article EN cc-by International Journal of Gynecology & Obstetrics 2018-10-01

10.1016/s0020-7292(12)60024-1 article EN International Journal of Gynecology & Obstetrics 2012-09-21

Endometrial cancer is the most common gynecological malignancy in high- and middle-income countries. Although overall prognosis relatively good, high-grade endometrial cancers have a tendency to recur. Recurrence needs be prevented since for recurrent dismal. Treatment tailored tumor biology optimal strategy balance treatment efficacy against toxicity. Since The Cancer Genome Atlas defined four molecular subgroups of cancers, factors are increasingly used define treatment. Standard consists...

10.1002/ijgo.13866 article EN cc-by International Journal of Gynecology & Obstetrics 2021-10-01

In the context of COVID-19 pandemic, specific recommendations are required for management patients with gynecologic cancer.The FRANCOGYN group National College French Gynecologists and Obstetricians (CNGOF) convened to develop based on consensus conference model.If a patient cancer presents COVID-19, surgical should be postponed at least 15 days. For cervical cancer, radiotherapy concomitant radiochemotherapy could replace surgery as first-line treatment value lymph node staging reviewed...

10.1016/j.jogoh.2020.101729 article EN cc-by-nc-nd Journal of Gynecology Obstetrics and Human Reproduction 2020-04-01

Identification of aggressive endometrioid endometrial carcinomas (EECs) and non-endometrioid (NEECs) is essential to improve outcome. L1 cell adhesion molecule (L1CAM) expression a strong prognostic marker in stage I EECs, but less known about L1CAM advanced-stage EECs NEECs. This study analyses clinically representative cohort carcinomas.The was immunohistochemically determined 1199 carcinomas, treated at one the European Network for Individualized Treatment Endometrial Cancer (ENITEC)...

10.1038/bjc.2016.235 article EN cc-by-nc-sa British Journal of Cancer 2016-08-09

Importance Vacuum aspiration is commonly used to remove retained products of conception in patients with incomplete spontaneous abortion. Scarring the uterine cavity may occur, potentially impairing future fertility. A procedural alternative, operative hysteroscopy, has gained popularity a presumption better Objective To assess superiority hysteroscopy vacuum for subsequent pregnancy abortion who intend have pregnancy. Design, Setting, and Participants The HY-PER randomized, controlled,...

10.1001/jama.2023.3415 article EN JAMA 2023-04-11

The upper two-thirds of the uterus above level internal cervical os is called corpus. fallopian tubes enter at lateral corners a pear-shaped body. portion muscular organ that line joining tubo-uterine orifices often referred to as fundus. major lymphatic trunks are utero-ovarian (infundibulopelvic), parametrial, and presacral, which drain into hypogastric, external iliac, common para-aortic nodes. Although direct route spread from corpus uteri nodes through infundibulopelvic ligament has...

10.1016/j.ijgo.2015.06.005 article EN cc-by-nc-nd International Journal of Gynecology & Obstetrics 2015-09-30

Endometrial carcinoma mortality is mainly caused by recurrent disease, and various immunohistochemical markers to predict recurrences have been studied. Loss of the estrogen receptor (ER) progesterone (PR) presence L1 cell adhesion molecule (L1CAM) are promising markers, but their combined value has not studied.Expression ER, PR, L1CAM was immunohistochemically determined in 293 endometrial carcinomas from 11 collaborating European Network for Individualized Treatment Cancer centers....

10.1097/igc.0000000000001187 article EN cc-by-nc-nd International Journal of Gynecological Cancer 2018-01-11

Background Bayesian networks (BNs) are machine-learning–based computational models that visualize causal relationships and provide insight into the processes underlying disease progression, closely resembling clinical decision-making. Preoperative identification of patients at risk for lymph node metastasis (LNM) is challenging in endometrial cancer, although several biomarkers related to LNM, none them incorporated practice. The aim this study was develop externally validate a preoperative...

10.1371/journal.pmed.1003111 article EN cc-by PLoS Medicine 2020-05-15

Objective. To study incidence of abnormal hysteroscopic findings according to age. Methods. We retrospectively studied 557 consecutive office hysteroscopies in patients referred for incapacity conceive lasting at least 1 year or prior vitro fertilization. Rates were reviewed Results. In 219 cases, hysteroscopy showed an abnormality and more than a third our population had that could be related infertility. ranged from 30% 30 years 60% after 42 years. Risk finding was multiplied by factor 1.5...

10.1155/2010/168096 article EN cc-by Obstetrics and Gynecology International 2010-01-01

Introduction Cardiotocography, which consists in monitoring the fetal heart rate as well uterine activity, is widely used clinical practice to assess wellbeing during labor and delivery order detect hypoxia intervene before permanent damage fetus. We present DeepCTG® 1.0, a model able predict acidosis from cardiotocography signals. Materials methods 1.0 based on logistic regression fed with four features extracted last available 30 min segment of signals: minimum maximum values baseline,...

10.3389/fped.2023.1190441 article EN cc-by Frontiers in Pediatrics 2023-06-15
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