A5058006370- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Gastrointestinal Bleeding Diagnosis and Treatment
- Inflammatory Bowel Disease
- Gastrointestinal Tumor Research and Treatment
- Liver Disease Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Colorectal Cancer Screening and Detection
- Microscopic Colitis
- Head and Neck Cancer Studies
- Liver Disease and Transplantation
- Gallbladder and Bile Duct Disorders
- Neuroendocrine Tumor Research Advances
- Pancreatitis Pathology and Treatment
- Helicobacter pylori-related gastroenterology studies
- Clinical Nutrition and Gastroenterology
- Eosinophilic Esophagitis
- Tracheal and airway disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Lung Cancer Research Studies
- Biliary and Gastrointestinal Fistulas
Far Eastern Memorial Hospital
2016-2025
Taiwan Nurses Association
2015-2025
Fu Jen Catholic University
2015-2024
Linkou Chang Gung Memorial Hospital
2024
Virginia Mason Medical Center
2023
National Taiwan University Hospital
2008-2022
Ten Chen Hospital
2021
University of Missouri Health System
2020
3C Institute
2015
Memorial Hospital of South Bend
2013-2014
Several studies suggested that colonic microbiota have impacts on irritable bowel syndrome (IBS) patients. However, the knowledge about association of small intestine (SI) with IBS is limited. We aimed to investigate gut composition SI and stool in patients.Biopsies jejunum mucosa by balloon-assisted enteroscopy faecal samples from 28 patients 19 healthy controls were analysed next-generation sequencing method.The three major phyla case/control groups Proteobacteria (32.8/47.7%),...
This study uses hyperspectral imaging (HSI) and a deep learning diagnosis model that can identify the stage of esophageal cancer mark locations. simulates spectrum data from image using an algorithm developed in this which is combined with for classification single-shot multibox detector (SSD)-based identification system. Some 155 white-light endoscopic images 153 narrow-band were used to evaluate prediction model. The took 19 s predict results 308 test accuracy WLI NBI was 88 91%,...
Abstract Purpose Acute severe ulcerative colitis (ASUC) is a medical emergent condition, and approximately one-third of patients with ASUC do not respond to corticosteroid. Whether small molecule drugs are efficient safe for salvage therapy well-understood. Methods Consecutive who failed responding first-line corticosteroid were retrospectively enrolled. Clinical, laboratory, endoscopic, pathological data analyzed. Results Five Asian male (median age 38.9 years old) received upadacitinib The...
Diagnosis of early esophageal neoplasia, including dysplasia and superficial cancer, is a great challenge for endoscopists. Recently, the application artificial intelligence (AI) using deep learning in endoscopic field has made significant advancements diagnosing gastrointestinal cancers. In present study, we constructed single-shot multibox detector convolutional neural network different histological grades neoplasms evaluated diagnostic accuracy this computer-aided system. A total 936...
Risk factors for mortality in acute variceal hemorrhage remain incompletely understood. Whether endoscopy timing is associated with risk of has not been investigated. We aimed to investigate in-hospital cirrhotic patients hemorrhage, emphasis on timing.Three hundred and eleven (73% male 23% female) consecutive presenting from July 2004 2007 were The univariate association as the predictor was examined. Independent determined by multivariate logistic regression analysis consisting clinical,...
Abstract Background This nationwide prospective registry study investigated the real-world effectiveness, safety, and persistence of vedolizumab (VDZ) in inflammatory bowel disease (IBD) patients Taiwan. Disease relapse rates after VDZ discontinuation due to reimbursement restriction were assessed. Methods Data collected prospectively (January 2018 May 2020) from Taiwan Society IBD registry. Results Overall, 274 (147 ulcerative colitis [UC] patients, 127 Crohn’s [CD] patients) included....
Abstract Background Crohn’s disease (CD) is a progressive condition, and early treatment with infliximab combined an immunosuppressant within six months has been shown to improve clinical outcomes. However, the impact of ustekinumab (UST) use in biologic-naïve CD patients remains unclear. This study aims address this gap by evaluating outcomes UST intervention such patients. Methods In retrospective cohort study, we included treated UST, follow-up period at least months, from October 2020...
Abstract Background Thromboembolism (TE) notably increase morbidity and mortality among inflammatory bowel disease (IBD) patients. Despite ECCO's 2024 guidelines advocating routine anticoagulant prophylaxis, its application in Asia remains inconsistent due to a lack of regional studies. This research investigates the incidence predictors TE during IBD-related hospitalizations Taiwan, aiming improve prevention strategies. Methods Our retrospective cohort study included 282 adult IBD patients,...
Despite industrialization and advances in healthcare, the prevalence of inflammatory bowel disease (IBD), which encompasses Crohn's (CD) ulcerative colitis (UC), is increasing Taiwan. Population-based studies can estimate incidence or IBD; however, there a lack information regarding phenotype. Therefore, this study was designed to investigate epidemiologic trends IBD Taiwan gain more comprehensive understanding. Patient data were reviewed from prospectively registered by Society (TSIBD). We...
Background/Objectives: Crohn’s disease (CD) is a progressive condition, and early treatment with infliximab combined an immunosuppressant within six months has been shown to improve clinical outcomes. However, the impact of ustekinumab (UST) use in biologic-naïve CD patients remains unclear. This study aims address this gap by evaluating outcomes UST intervention such patients. Methods: In retrospective cohort study, we included treated UST, follow-up period at least from October 2020...
Introduction Patients with head and neck cancer may develop a second primary neoplasm (SPN) of the esophagus due to field cancerization. This study investigated impacts esophageal screening using magnifying endoscopy narrow-band imaging (ME-NBI) on outcomes hypopharyngeal patients. Methods diagnosed from 2008 2021 in tertiary hospital were reviewed retrospectively. Screening surveillance ME-NBI examination divided into three patterns: (1) never performed or more than 6 months after diagnosis...
Treatment strategy of esophageal cancer mainly depends on accurate staging. At present, no single ideal staging modality is superior to another in preoperative tumor-node-metastasis (TNM) patients with cancer. We aimed investigate the efficacy endoscopic ultrasonography (EUS) and positron emission tomography-computed tomography (PET-CT) for retrospectively studied 118 consecutive squamous cell carcinoma who underwent esophagectomy or without neoadjuvant chemoradiotherapy (CRT) over a near...
Abstract Background The prevalence of esophageal neoplasia in head and neck (H&N) cancer patients is not low; however, routine surveillance included staging newly-diagnosed H&N cancers. We aimed to investigate the risk factors for synchronous impact endoscopy on management patients. Methods A total 129 newly diagnosed who underwent with white-light imaging, narrow-band imaging (NBI) magnifying (ME), chromoendoscopy 1.5% Lugol’s solution, before definite treatment were enrolled...
Background Head and neck cancer (HNC) is associated with a high rate of developing second primary malignancies(SPMs). But the impact on survival remains poorly understood before. Therefore, we want to estimate SPMs HNC survivors. Methods Findings Between 1986 2008, total 9,996 were recorded for 93,891 patients an initial diagnosis by Taiwan Cancer Registry. Patients followed national death registry database 2011.Using Kaplan–Meier method, time-dependent covariate was employed compare rates...
Gastric neuroendocrine tumors (GNETs) are a heterogeneous group of neoplasm with varying biological characteristics. This study aimed to investigate the clinical features and outcomes GNET patients after endoscopic diagnosis treatment in multicenter registry. Patients GNETs confirmed histologically were recruited from 17 hospitals between January 2010 April 2016 Taiwan. Clinical, laboratory, radiological, endoscopic, pathological data, strategies, follow-up periods, survivals collected...
Limited studies have addressed the exacerbation of symptoms and long COVID in inflammatory bowel disease (IBD) patients following non-severe COVID-19 infection, particularly with post-COVID-19 vaccination. We aim to investigate factors associated exacerbated gastrointestinal (EGS) IBD COVID-19, which is most common situation daily practice. This an observational study by multiple centers Taiwan from May 2020 March 2023. collected clinical manifestation, data, medication information COVID-19....
No data has been available on prophylaxis for stress ulcer development during the process of weaning patients off mechanical ventilators. We conducted a randomized study to evaluate efficacy with lansoprazole OD in being weaned from ventilators.A total 120 were randomly allocated into two groups using blocked randomization, 60 each group. Group A was treatment group, receiving 30 mg nasogastric tube 14 days, while B, control received no proton pump inhibitors or other medications treating...
Foci of heterotopic gastric mucosa have been identified at different sites in the human body and most common location is proximal esophagus which referred to as cervical inlet patch (CIP). The true prevalence CIP varies it usually incidental findings during endoscopy. Because always asymptomatic, was believed be little clinical relevance. However, emerging studies described acid-secreting characteristics associations with gastroesophageal reflux disease (GERD). In addition, complications...
Small bowel (SB) accounts for the majority of gastrointestinal tract but its tumors are rare and always overlooked. In this study, we aimed to evaluate epidemiology SB tumors. This multicenter retrospective study utilized endoscopy database from 2006/11 2016/07. Baseline demographic characteristics, clinical, radiologic endoscopic findings were collected. Totally 103 (34 benign, 69 malignant lesions) patients with in 1070 enteroscopic examinations enrolled. There male preponderance (56.3%...