Jianzhong Wang

ORCID: 0000-0001-9227-0806
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Research Areas
  • Viral gastroenteritis research and epidemiology
  • Influenza Virus Research Studies
  • Animal Virus Infections Studies
  • Spine and Intervertebral Disc Pathology
  • Medical Imaging and Analysis
  • Immune Response and Inflammation
  • Gut microbiota and health
  • Probiotics and Fermented Foods
  • Virus-based gene therapy research
  • Immune Cell Function and Interaction
  • Spinal Fractures and Fixation Techniques
  • Antimicrobial Peptides and Activities
  • Nanoplatforms for cancer theranostics
  • Coccidia and coccidiosis research
  • Respiratory viral infections research
  • Parasitic Diseases Research and Treatment
  • Animal Disease Management and Epidemiology
  • Algal biology and biofuel production
  • Musculoskeletal pain and rehabilitation
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Advanced Nanomaterials in Catalysis
  • SARS-CoV-2 and COVID-19 Research
  • Antimicrobial agents and applications
  • Parasite Biology and Host Interactions
  • Photodynamic Therapy Research Studies

Shanxi Agricultural University
2023-2025

Flinders University
2024

Jilin Agricultural University
2016-2024

Second Affiliated Hospital of Inner Mongolia Medical University
2024

First Affiliated Hospital of Anhui Medical University
2018-2023

Anhui Medical University
2018-2023

Affiliated Hospital of Hebei University
2020-2023

Guangzhou University of Chinese Medicine
2022

Wenzhou Medical University
2022

Tianjin Medical University
2021

Eimeria spp. are responsible for chicken coccidiosis which is the most important enteric protozoan disease resulting in tremendous economic losses poultry industry. Understanding interaction between avian cecal microbiota and coccidia of interest development alternative treatments that do not rely on chemotherapeutics lead to drug resistance.We utilized 16S rRNA gene sequencing detect dynamics microbial community AA broilers challenged with tenella. Histopathological analysis cecum was also...

10.1186/s13071-020-3897-6 article EN cc-by Parasites & Vectors 2020-02-11

In the quest to curtail spread of healthcare-associated infections, this work showcases fabrication a cutting-edge antibacterial textile coating armoured with aggregation-induced emission photosensitisers (AIE PS) prevent bacterial colonisation on textiles. The adopted methodology includes multi-step process using plasma polymerisation and subsequent integration AIE PS their surface. effectiveness was tested against Pseudomonas aeruginosa Staphylococcus aureus after light irradiation for 1...

10.3390/molecules29061209 article EN cc-by Molecules 2024-03-08

Abstract Surgical site infections (SSI) are major post‐operative complications following surgery. Reducing SSI is a global urgency as they account for huge pecuniary, physiological, and emotional burdens patients. Antibiotic resistance the main challenge surgeons dealing with SSIs. Aggregation‐induced emission photosensitisers (AIE PS) their distinct optical characteristics, biocompatibility, low toxicity, target specificity, hold potential treatment of SSI. Herein, synergetic strategy...

10.1002/admi.202400053 article EN cc-by Advanced Materials Interfaces 2024-03-08

Background Thalassemia is the most common inherited disease in southern China. However, this disorder usually ignored by Jiangxi provincial health system and government due to lack of epidemiological data. Materials Methods A total 9489 samples from Hakka Han Gan-speaking three geographical areas Province were analyzed for both complete blood cell (CBC) count reverse dot blot (RDB) gene chip thalassemia. Results 1182 cases suspected thalassemia carriers with microcytosis (MCV<82 fL) found...

10.1371/journal.pone.0101505 article EN cc-by PLoS ONE 2014-07-07

ABSTRACT In maintaining organismal homeostasis, gut immunity plays a crucial role. The coordination between the microbiota and immune system through bidirectional interactions regulates impact of microorganisms on host. Our research focused understanding relationships substantial changes in jejunal intestinal flora metabolites during porcine epidemic diarrhea virus (PEDV) infection piglets. We discovered that Lactobacillus rhamnosus GG ( LGG ) could effectively prevent PEDV Further...

10.1128/jvi.01039-24 article EN Journal of Virology 2024-07-16

Abstract Gut microbes play an important role in the development of host B cells. It has been controversial whether GALT is site cells pigs. By investigating relationship between gut and piglets, we found, to our knowledge for first time, that early exist lamina propria (LP) pigs at different ages. We further used Lactobacillus rhamnosus GG (LGG) treat piglets. The results showed LGG promotes lineage, affects composition Ig CDR3 repertoires cells, production IgA intestinal LP. Additionally,...

10.4049/jimmunol.2100102 article EN The Journal of Immunology 2021-09-08

There are some limitations of traditional influenza vaccines concerning novel mutant strains. Therefore, it is particularly important to develop preventive means for antigen-unrelated types viruses. Recent studies have shown that probiotics can modulate the immune system and reduce severity viral infections. In this study, we investigated potential Lactiplantibacillus plantarum 0111 against virus H9N2. Challenge experiments showed L. pretreatments could effectively improve mice’s survival...

10.3389/fmicb.2022.820484 article EN cc-by Frontiers in Microbiology 2022-06-30

Avian influenza virus (AIV) subtype H9N2 has significantly threatened the poultry business in recent years by having become predominant flocks of chickens, ducks, and pigeons. In addition, public health aspects AIV pose a significant threat to humans. Early rapid diagnosis is therefore great importance. this study, new method for detection based on fluorescence intensity was successfully established using CRISPR/Cas13a technology. The Cas13a protein first expressed prokaryotic system...

10.1016/j.psj.2024.104068 article EN cc-by-nc-nd Poultry Science 2024-07-09

Abstract Mass production of microalgae is a research focus owing to their promising aspects for sustainable food, biofunctional compounds, nutraceuticals, and biofuel feedstock. This study uses novel approach enhance microalgae‐derived biomass metabolites by using an aggregation‐induced emission (AIE) photosensitizer (PS), CN‐TPAQ‐PF 6 ([C 32 H 23 N 4 ] + ). The unique AIE features facilitate nano‐aggregation in aquatic media effective light spectral shift photosynthetic augmentation green...

10.1002/smll.202402463 article EN cc-by Small 2024-08-19

Minicircle DNA (mcDNA), which contains only the necessary components for eukaryotic expression and is thus smaller than traditional plasmids, has been designed application in genetic manipulation. In this study, we constructed a novel plasmid containing both Cre recombinase under phosphoglycerate kinase (PGK) promoter recombinant lox66 lox71 sites located outside cytomegalovirus (CMV) cassette. The strictly controlled synthesis of vivo maintained complete form vitro, whereas production...

10.1128/aem.00407-19 article EN Applied and Environmental Microbiology 2019-05-06

Avian influenza viruses can be efficiently transmitted through mucous membranes, and conventional vaccines are not effective in protecting against mucosal infection by viruses. To induce multiple immune responses an organism, we constructed a recombinant Lactobacillus plantarum expressing the virus antigen HA1 with adjuvant dendritic cell-targeting peptide (DCpep). The L. strains NC8Δ-pWCF-HA1 NC8Δ-pWCF-HA1-DCpep were used to immunize mice via oral administration, humoral, cellular...

10.3389/fimmu.2021.800965 article EN cc-by Frontiers in Immunology 2021-12-01
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