A5028889141- Animal Virus Infections Studies
- Viral Infections and Immunology Research
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Plant-Microbe Interactions and Immunity
- Influenza Virus Research Studies
- Animal Disease Management and Epidemiology
- Legume Nitrogen Fixing Symbiosis
- Plant Virus Research Studies
- Microbial infections and disease research
- Bacteriophages and microbial interactions
- Microbial Community Ecology and Physiology
- Gut microbiota and health
- Herpesvirus Infections and Treatments
- Gallbladder and Bile Duct Disorders
- Soil Carbon and Nitrogen Dynamics
- Hepatitis C virus research
- Nematode management and characterization studies
- Mycorrhizal Fungi and Plant Interactions
- Amoebic Infections and Treatments
- CRISPR and Genetic Engineering
- DNA Repair Mechanisms
- Biliary and Gastrointestinal Fistulas
- Genomics and Phylogenetic Studies
- RNA and protein synthesis mechanisms
Northeast Institute of Geography and Agroecology
2017-2025
Chinese Academy of Sciences
2010-2025
Fujian Academy of Agricultural Sciences
2013-2024
China Automotive Technology and Research Center
2024
Shanghai Ninth People's Hospital
2018-2023
Shanghai Jiao Tong University
2018-2023
Animal Science Research Institute
2009-2022
Anhui Academy of Agricultural Sciences
2022
Institute of Microbiology
2022
Animal Husbandry & Veterinary
2011-2021
Background. Bacteremias, which are often caused by gram‐negative bacteria, the most frequently occurring infectious complications after liver transplantation (LT). The aim of this study was to investigate bacteremic incidence, pathogenic spectrum, risk factors for bacteremia due multidrug resistant (MDR) bacilli, and its impact on mortality LT. Methods. A cohort analysis prospectively recorded data done in 475 LT recipients, who were divided into 3 categories: cases with bacteremia, MDR...
Abstract Background Trichoderma reesei is the preferred organism for producing industrial cellulases. However, a more efficient heterologous expression system enzymes from different needed to further improve its cellulase mixture. The strong cbh1 promoter of T. frequently used in expression, however, carbon catabolite repressor CREI may reduce strength by binding at several sites. Another crucial point enhance production stability recombinant mRNA and prevention protein degradation within...
Abstract Mammalian shelterin proteins POT1 and TPP1 form a stable heterodimer that protects chromosome ends regulates telomerase-mediated telomere extension. However, how interacts with remains unknown. Here we present the crystal structure of C-terminal portion human (POT1C) complexed POT1-binding motif TPP1. The shows POT1C contains two domains, third OB fold Holliday junction resolvase-like domain. Both domains are essential for binding to Notably, unlike heart-shaped ciliated protozoan...
Abstract Background The assembly of the rhizomicrobiome, i.e., microbiome in soil adhering to root, is influenced by conditions. Here, we investigated core rhizomicrobiome a wild plant species transplanted an identical type with small differences chemical factors and impact these chemistry on after long-term cultivation. We sampled three natural reserve populations rice (i.e., situ) situ grown ex for more than 40 years determine rhizomicrobiome. Results Generalized joint attribute modeling...
Ribonuclease P (RNase P) is a universal ribozyme responsible for processing the 5'-leader of pre-transfer RNA (pre-tRNA). Here, we report 3.5-angstrom cryo-electron microscopy structures Saccharomyces cerevisiae RNase alone and in complex with pre-tRNAPhe The protein components form hook-shaped architecture that wraps around stabilizes into "measuring device" two fixed anchors recognize L-shaped pre-tRNA. A universally conserved uridine nucleobase phosphate backbone catalytic center together...
Crop domestication has revolutionized food production but increased agriculture's reliance on fertilizers and pesticides. We investigate differences in the rhizosphere microbiome functions of wild domesticated rice, focusing nitrogen (N) cycling genes. Shotgun metagenomics real-time PCR reveal a higher abundance N-fixing genes rice microbiomes. Validation through transplanting suspensions shows highest nitrogenase activity soils with suspensions, regardless planted type. Domesticated...
The exchange of support between generations is a fundamental feature intergenerational relationships. Although most studies have concentrated on the impact social receiver, effects subjective well-being provider been studied less often. Given cultural differences in norms and values relationships, present study compared samples from rural urban China, Indonesia, Germany. results showed that different contexts elderly mothers’ was differently related to help they provided their adult...
Since 2003, H5N1-subtype avian influenza viruses (AIVs) with both a deletion of 20 amino acids in the stalk neuraminidase (NA) glycoprotein (A−) and five at positions 80 to 84 non-structural protein NS1 (S−) have become predominant. To understand influence these double deletions NA proteins on pathogenicity AIVs, we selected A/mallard/Huadong/S/2005 as parental strain generate rescued wild-type A−S− three variants (A−S+ five-amino-acid insertion protein, A+S− 20-amino-acid stalk, A+S+...
Abstract Ribonuclease P (RNase P) is an essential ribozyme responsible for tRNA 5′ maturation. Here we report the cryo-EM structures of Methanocaldococcus jannaschii ( Mja ) RNase holoenzyme alone and in complex with a substrate at resolutions 4.6 Å 4.3 Å, respectively. The reveal that subunits are strung together to organize dimeric conformation required efficient catalysis. also show archaeal functional chimera bacterial eukaryal Ps possesses bacterial-like two RNA-based anchors...
Coriolus versicolor (C. versicolor) is a higher fungi or mushroom which now known by its accepted scientific names as Trametes (L.) Lloyd. Many studies have shown that β-glucans from C. various physiological activities, including activating macrophages to protect against Salmonella infection. However, whether antiviral effects has not been reported. Hence, the objective of this study was confirm could boost immune response combat influenza virus in mouse and chick models. The results show...
Glomus intraradices is a species of arbuscular mycorrhizal fungi that, as an obligate endomycorrhiza, can form mutually beneficial associations with plants. Panax ginseng popular traditional Chinese medicine; however, problems associated planting, such pesticide residues, reduce the quality. In this experiment, we studied effect inoculating G. on several physiological properties and microbial communities ginseng. UV-Visible Spectrum method was used to detect physical properties. Denaturing...