A5063401977- Inflammatory Bowel Disease
- Microscopic Colitis
- Pancreatitis Pathology and Treatment
- Gastrointestinal Tumor Research and Treatment
- Pancreatic and Hepatic Oncology Research
- Gastric Cancer Management and Outcomes
- Autoimmune and Inflammatory Disorders
- Gastrointestinal Bleeding Diagnosis and Treatment
- Colorectal Cancer Screening and Detection
- Eosinophilic Esophagitis
- Colorectal Cancer Treatments and Studies
- Systemic Lupus Erythematosus Research
- Liver Diseases and Immunity
- Amoebic Infections and Treatments
- Nutrition and Health in Aging
- Helicobacter pylori-related gastroenterology studies
- Appendicitis Diagnosis and Management
- Gastrointestinal disorders and treatments
- Pregnancy and Medication Impact
- Chronic Myeloid Leukemia Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Case Reports on Hematomas
- Abdominal vascular conditions and treatments
- Infectious Diseases and Tuberculosis
- Ultrasound and Hyperthermia Applications
Kitasato University
2022-2024
Kitasato Institute Hospital
2022-2024
Toho University
2017-2024
Toho University Omori Medical Center
2017-2024
Ghent University Hospital
2011
Mount Vernon Cancer Centre
2011
Hospital Santa Marcelina
2011
Hospital São Paulo
2011
Nihon University
2011
The University of Texas MD Anderson Cancer Center
2011
Introduction: A large proportion of small bowel lesions in Crohn’s disease (CD) may exist beyond the reach ileocolonoscopy and there is no gold standard imaging modality to screen them, suggesting need for optimal biomarkers. We aimed compare usefulness C-reactive protein (CRP), faecal calprotectin (FC), leucine-rich alpha-2 glycoprotein (LRG) determining CD. Methods: This was a cross-sectional observational study. CRP, FC, LRG were prospectively measured patients with quiescent CD who...
Leucine-rich α-2-glycoprotein (LRG) is a new serum biomarker reflecting the disease activity of ulcerative colitis (UC), but its change during acute phase has not been enough investigated.
The efficacy of endoscopic submucosal dissection (ESD) for early-stage gastric cancer is well established. However, its acquisition challenging owing to complexity. In Japan, G-Master a novel ex vivo ESD training model. effectiveness using unknown. This study evaluated the evaluate trainees' learning curves and performance.
ABSTRACT Background Intestinal ultrasound (IUS) is a non‐invasive tool for evaluating transmural inflammation in Crohn's disease (CD). However, its utility constrained by operator dependency and limited accessibility. Aims To explore the feasibility of serum biomarkers—specifically leucine‐rich alpha‐2 glycoprotein (LRG)—as an alternative to IUS assessing inflammation. Methods This retrospective, single‐centre study included patients with CD who underwent measurements LRG C‐reactive protein...
Introduction Filgotinib is a JAK-1 selective inhibitor approved for ulcerative colitis (UC) treatment in Japan. Its effectiveness has been confirmed but remains unknown actual clinical practice. Therefore, we aimed to evaluate the and safety of filgotinib identify suitable patients Japanese population. Methods We retrospectively reviewed background, course, laboratory data treated with 200 mg UC between May 2022 December 2023. Results The median observation period 25 was 232 days...
Bowel ultrasound is a noninvasive alternative to endoscopy for assessing the disease activity of ulcerative colitis; however, it unclear whether bowel can predict subsequent relapse from remission.A retrospective cohort study enrolled patients with colitis who underwent between July 2018 and 2021 during clinical remission (patient-reported outcome-2 ≤1 no rectal bleeding) at least 3 months were followed up 1 year. Ultrasonographic findings (bowel wall thickness, flow, stratification,...
Abstract Background Endoscopic remission is associated with better long-term outcomes of ulcerative colitis (UC), and therefore, it considered a treatment target. However, endoscopy invasive frequent monitoring not feasible. We have reported that bowel ultrasound (BUS) useful in predicting endoscopic histologic severity determining response to (Sagami S et al, APT 2020 & 2022). unclear whether BUS can predict the relapse UC remission. Methods conducted retrospective cohort study...
Abstract Background Endoscopy has been used to assess the disease activity of Crohn's (CD) but may not be sufficient considering transmural nature its inflammation. Bowel ultrasonography (BUS) reported reflect CD and long-term outcomes. We performed a prospective study determine whether BUS can predict short-term clinical response induction therapy. Methods Consecutive patients with active ulcers in endoscopy requiring therapy (Anti-TNF antibody, IL-12/23 p40 integrin inhibitor,...
Abstract Background Thiopurines are useful to maintain remission for ulcerative colitis (UC) and inhibit immunogenicity in combination with biologics while their long-term use may increase risks of infections malignancies. Therefore, the risk-benefit balance should be evaluated, de-escalation needs discussed. However, optimal strategy such as dosing monitoring has not been well studied. Methods UC patients clinical (partial Mayo score ≤ 2 rectal bleeding subscore 0) who de-escalated...
<b><i>Introduction:</i></b> We investigated the hemostatic effect and safety of a peptide solution for treatment gastrointestinal bleeding requiring emergency endoscopy. <b><i>Methods:</i></b> retrospectively examined patient backgrounds, results, procedural in patients who were treated with hemostasis during endoscopies bleeding. All procedures performed by nonexpert physicians less than 10 years endoscopic experience. cases at single...
A 74-year-old man had experienced dyspnea. Contrast-enhanced CT confirmed bilateral pleural effusion, pericardial and accumulation of 31×19 mm fluid under the diaphragm. Due to high amylase levels in effusion fluid, a pancreatic was suspected. On day 15, ERCP performed, which showed narrowed duct body, with leakage contrast agent from body. We diagnosed fistula performed 5Fr ENPD. 21, it replaced 7-Fr stent ; however, little improvement, increased effusion. 42, 10-Fr stent, somatostatin...
A 66-year-old man with a history of Billroth II procedures for duodenal ulcer presented to our department obstructive jaundice due unresectable pancreatic cancer.
We report a case of small intestinal ulcer with active bleeding stopped by colonoscopy.
Vascular complications from a liver abscess are rare but life-threatening. Herein, we report the case of man in his 40s with pyogenic hepatic complicated by an inferior vena caval thrombus extending to right atrium. His presenting complaint was high fever. Blood tests revealed elevated inflammatory markers and enzymes. An abdominal CT demonstrated 10cm lobe. A blood culture grew Streptococcus intermedius, which sensitive ampicillin sulbactam. He diagnosed treated metronidazole Three days...
Crohn's disease (CD) often causes intractable diarrhea after intestinal resection. Anion exchange resins have been reported to be effective in patients with bile acid distal ileectomy; furthermore, metabolism has implicated the pathogenesis of CD. Therefore, we aimed examine effectiveness colestimide management postoperative CD, and compare its impact between those without ileocecal resection.Postoperative CD prescribed for April 2017 December 2020 were retrospectively evaluated changes...
Abstract A large proportion of small bowel lesions in Crohn’s disease (CD) may exist beyond the scope ileocolonoscopy, suggesting need for optimal biomarkers. This cross-sectional observational study prospectively measured C-reactive protein (CRP), faecal calprotectin (FC), and leucine-rich alpha-2 glycoprotein (LRG) patients with quiescent CD who underwent imaging examinations (capsule or balloon-assisted endoscopy, magnetic resonance enterography, intestinal ultrasound). Mucosal healing...