A5115597276- Liver Disease Diagnosis and Treatment
- Liver physiology and pathology
- Enzyme Catalysis and Immobilization
- Electrochemical sensors and biosensors
- Appendicitis Diagnosis and Management
- Epigenetics and DNA Methylation
- Esophageal and GI Pathology
- Immune cells in cancer
- Iron oxide chemistry and applications
- Microplastics and Plastic Pollution
- Additive Manufacturing and 3D Printing Technologies
- Organ Transplantation Techniques and Outcomes
- Minimally Invasive Surgical Techniques
- Origins and Evolution of Life
- Advanced Materials and Mechanics
- Intestinal and Peritoneal Adhesions
- Advanced Optical Sensing Technologies
- Hydrogen Storage and Materials
- Nanofabrication and Lithography Techniques
- Phosphorus and nutrient management
- Gut microbiota and health
- Genomics, phytochemicals, and oxidative stress
- Gait Recognition and Analysis
- Graphene and Nanomaterials Applications
- Superconductivity in MgB2 and Alloys
China Agricultural University
2025
Second Affiliated Hospital of Harbin Medical University
2014-2024
Chengdu University
2024
Harbin Medical University
2014-2024
Henan Provincial People's Hospital
2024
Harbin Institute of Technology
2024
Tiangong University
2024
Zhengzhou University
2024
Neusoft (China)
2024
Chengdu Neusoft University
2024
During tumor development, the itself must continuously generate new blood vessels to meet their growth needs while also allowing for invasion and metastasis. One of most common features tumors is hypoxia, which drives process angiogenesis by regulating microenvironment, thus adversely affecting prognosis patients. In addition, overcome unsuitable environments growth, such as nutrient deficiency, hyperacidity, immunosuppression, microenvironment (TME) coordinates in several ways restore...
Ulcerative colitis (UC) is a chronic disease characterized by mucosal and submucosal inflammation, which has low cure rate prone to relapse, due the immune imbalance of body. Inhibition inflammation-related pathways can delay progression UC. Toll-like receptor 4 (TLR4) pathway considered be one important signaling involved in colon inflammation. Eriodictyol (EDT) natural flavonoid widely distributed foodborne plants. EDT plays an role regulation inflammation related pathways. However,...
Circular RNAs (circRNAs) are crucial non-coding in the process of tumorigenesis. Nevertheless, biological function circ_0004277 acute myeloid leukemia (AML) is blurred. Microarray data circRNAs were utilized to evaluate circRNAs' differential expression AML. Quantitative real-time polymerase chain reaction (qRT-PCR) was executed determine and microRNA-134-5p (miR-134-5p) levels. The growth, migration invasion AML cells tested by cell counting kit-8 Transwell experiment. Dual-luciferase...
Knowledge of the interfacial interactions between aspartate and minerals, especially its competition with phosphate, is critical to understanding fate transport amino acids in environment. Adsorption reactions play important roles mobility, bioavailability, degradation phosphate. Attenuated total reflectance Fourier-transform infrared (ATR-FTIR) measurements density functional theory (DFT) calculations were used investigate structures their relative contributions single-adsorbate systems....
Hair follicle-derived mesenchymal stem cells (HF-MSCs) show considerable therapeutic potential for liver cirrhosis (LC). To improve the effectiveness of naïve HF-MSC treatments on LC, we used bioinformatic tools to identify an exogenous gene targeting HSCs among differentially expressed genes (DEGs) in LC modify HF-MSCs. Extracellular matrix protein 1 (ECM1) was identified as a DEG that significantly downregulated cirrhotic liver. Then, ECM1-overexpressing HF-MSCs (ECM1-HF-MSCs) were...
Lysine adsorption at clay/aqueous interfaces plays an important role in the mobility, bioavailability, and degradation of amino acids environment. Knowledge these interfacial interactions facilitates our full understanding fate transport acids. Here, X-ray diffraction (XRD) attenuated total reflectance Fourier-transform infrared spectroscopy (ATR-FTIR) measurements were used to explore dynamic process lysine on montmorillonite competition with Ca(2+) molecular level. Density functional...
Hepatocellular carcinoma (HCC) represents a common neoplasm that presents substantial worldwide health challenge. Nevertheless, the involvement of HPN-AS1 in HCC remains unknown. The quantitative reverse transcription polymerase chain reaction (qRT-PCR) assay was utilized to measure expression HCC. GABPA effects on promoter were analyzed through chromatin immunoprecipitation and luciferase reporter assays. Cell proliferation potential determined by deploying CCK-8 assay, Ki-67...
Bone marrow mesenchymal stromal cells (BMSCs) have a protective effect against liver cirrhosis. Long noncoding RNAs (lncRNAs) play crucial roles in the progression of Therefore, it is aimed to clarify lncRNA Kcnq1ot1 involved mechanism BMSCs This study found that treatment attenuates CCl4 -induced cirrhosis mice. Additionally, expression upregulated human and mouse tissues, addition TGF-β1-treated LX2 JS1 cells. The reversed with treatment. knockdown alleviated both vivo vitro. Fluorescence...
Researchers have shown that bone mesenchymal stem cells (BMSCs) can alleviate the progression of liver cirrhosis; however, it is unclear how exactly BMSCs function to cure disease. In this study, we used bioinformatics methods assess differentially expressed genes (DEGs) in cirrhosis and found a significantly upregulated gene, Fstl1, cirrhosis. vivo vitro experiments showed compared with those disease model group, mRNA, protein expression levels Fstl1 were reduced after treatment, β-Catenin...
A facile strategy was developed for the preparation of magnetically recyclable Co 2 P nanosheets with efficient catalytic activity NaBH 4 hydrolysis.
A new disulfide glycoside, raphthioglucoside (1), and a sinapic acid derivative, 5-hydroxymethylfurfural ester (2), together with (3) have been isolated from the seeds of Raphanus nussatirus L. The structures compounds 1-3 were determined based on chemical analysis spectroscopic methods (UV, 1D 2D NMR, HRFABMS, HREIMS elemental analysis).
Liver cirrhosis (LC) involves multiple systems throughout the body, and patients with LC often die of organ failure. However, few drugs are useful to treat LC. Hair follicle mesenchymal stem cells (HF-MSCs) derived from dermal papilla bulge area hair follicles pluripotent in mesoderm broad prospects regenerative medicine. As an emerging seed cell type widely used skin wound healing plastic surgery, HF-MSCs show considerable treatment due their proliferation multidirectional differentiation...