A5089857438- Mesenchymal stem cell research
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Body Contouring and Surgery
- Breast Implant and Reconstruction
- 3D Printing in Biomedical Research
- Pluripotent Stem Cells Research
- Cancer Cells and Metastasis
- Body Image and Dysmorphia Studies
- Surgical Sutures and Adhesives
- Organ and Tissue Transplantation Research
- Dermatologic Treatments and Research
- Reconstructive Surgery and Microvascular Techniques
- Breast Cancer Treatment Studies
- Wound Healing and Treatments
- Adipose Tissue and Metabolism
Universidade Federal de São Paulo
2015-2021
Tulane University
2016-2018
Louisiana State University
2018
Dillard University
2018
Decellularized human adipose tissue has potential clinical utility as a processed biological scaffold for soft cosmesis, grafting, and reconstruction. Adipose decellularization been accomplished using enzymatic-, detergent-, and/or solvent-based methods. To examine the hypothesis that distinct processes may yield scaffolds with differing compositions, current study employed mass spectrometry to compare proteomes of adipose-derived matrices generated through three independent methods...
Background: Adipose tissue is a source of adipose-derived stromal/stem cells for engineering and reconstruction fat grafts. Although liposuction simple procedure the harvest adipose tissue, repetition this surgical intervention can cause adverse effects to patient be limiting factor immediate use. Cryopreservation avoid morbidity associated with repetitive liposuction, allowing use stored after initial procedure. This article focuses on characterization fresh cryopreserved human tissue....
To analyze the histology and histomorphometry of healing associated with acellular dermal matrix in skin wounds rabbits.Twelve male rabbits were divided into two groups: control group (CG) (MG). Three a total area 20 × mm created on dorsal region each animal. Photographic records lesions taken over 21-day period use ImageJ program allowed calculation wound contraction rate. The biopsied days 3, 14 21 for histomorphometric analysis to define thicknesses dermis epidermis (hematoxylin-eosin)...
The capability of multipotent mesenchymal stem cells to maintain cell viability, phenotype and differentiation ability upon thawing is critical if they are be banked used for future therapeutic purposes. In the present study, we examined effect 9-10 months cryostorage on morphology, immunophenotype, colony-forming unit (CFU) capacity fresh cryopreserved human adipose-derived stromal/stem (ASCs) from same donors. Cryopreservation did not reduce CFU frequency expression levels CD29, CD73, CD90...
Adipose tissue is now recognized as a complex organ serving endocrine, immune, and metabolic functions. depots are composed of mature adipocytes well stromal vascular fraction (SVF) cells, heterogeneous population B T lymphocytes, endothelial macrophages, pericytes, smooth muscle, cells that can be isolated by enzymatic digestion. When placed into culture medium, subset the SVF adhere to plastic surface expand in number. This latter population, known "adipose-derived stromal/stem cells"...
Dermal fibroblasts (DFs) share several qualities with mesenchymal stem cell/multipotent stromal cells (MSCs) derived from various tissues, including adipose-derived stromal/stem (ASCs). ASCs and DFs are morphologically comparable both cell types can be culture expanded through the utilization of their plastic-adherence properties. Despite these similar characteristics, numerous studies indicate that ASC DF display distinct therapeutic benefits in clinical applications. To more accurately...