Lei Liu

ORCID: 0000-0001-9262-2103
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About
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Research Areas
  • Animal Nutrition and Physiology
  • Rabbits: Nutrition, Reproduction, Health
  • Adipose Tissue and Metabolism
  • Pharmacological Effects of Natural Compounds
  • Regulation of Appetite and Obesity
  • Biochemical effects in animals
  • Meat and Animal Product Quality
  • Gut microbiota and health
  • Biochemical Analysis and Sensing Techniques
  • Diet and metabolism studies
  • Hair Growth and Disorders
  • Moringa oleifera research and applications
  • Periodontal Regeneration and Treatments
  • Metabolism, Diabetes, and Cancer
  • Trace Elements in Health
  • Peroxisome Proliferator-Activated Receptors
  • Probiotics and Fermented Foods
  • Fatty Acid Research and Health
  • Viral gastroenteritis research and epidemiology
  • Pancreatic function and diabetes
  • Skin and Cellular Biology Research
  • Animal Virus Infections Studies
  • Selenium in Biological Systems
  • Urinary Bladder and Prostate Research
  • Lipid metabolism and biosynthesis

Ministry of Agriculture and Rural Affairs
2022-2025

Shandong Agricultural University
2015-2025

First Affiliated Hospital of Anhui Medical University
2020-2025

Anhui Medical University
2020-2025

Hunan Agricultural University
2016-2025

Chinese Academy of Agricultural Sciences
2020-2023

Sichuan Agricultural University
2018-2022

Environment and Plant Protection Research Institute
2022

Second Affiliated Hospital of Harbin Medical University
2022

Mudanjiang Medical University
2022

One of the main characteristics tomato (Solanum lycopersicum) fruit ripening is a massive accumulation carotenoids (mainly lycopene), which may contribute to nutrient quality and its role in chemoprevention. Previous studies have shown that ethylene (ET) plays central promoting ripening. In this study, jasmonic acid (JA) controlling lycopene fruits was analysed by measuring content expression levels biosynthetic genes JA-deficient mutants (spr2 def1) 35S::prosystemin transgenic line...

10.1093/jxb/ers224 article EN Journal of Experimental Botany 2012-09-03

This study aimed to evaluate the individual and combined effects of chemically protected sodium butyrate (CSB) xylo-oligosaccharide (XOS) on performance, anti-inflammatory antioxidant capacity, intestinal morphology microbiota broilers. A total 280 one-day-old Arbor Acres broilers were randomly distributed into 5 treatments: basal diet (CON), supplemented with 100 mg/kg aureomycin 8 enramycin (ABX), 1000 CSB (CSB), XOS (XOS), mixture (MIX), respectively. On d 21, ABX, CSB, MIX decreased feed...

10.1016/j.psj.2023.102585 article EN cc-by-nc-nd Poultry Science 2023-02-15

The aim of this paper was to investigate the effect heat stress on regulation appetite-associated genes in laying hens. Forty eight hens were randomly divided into two circumstances: high (31 ± 1.5°C; relative humidity, 82.0 2.2%) or normal (20 2°C, control; 60.1 4.5%) ambient environment. Heat decreased body weight gain (P < 0.01), feed intake rate 0.05), average egg mass production shell thickness and efficiency 0.05). High temperature plasma uric acid significantly increased mRNA levels...

10.1155/2012/484869 article EN Journal of Biomedicine and Biotechnology 2012-01-01

Short-chain fatty acids (SCFAs) (a microbial fermentation production in the rabbit gut) have an important role many physiological processes, which may be related to reduced body fat of rabbits. In present experiment, we study function acetate major SCFA on metabolism. Ninety rabbits (40 days age) were randomly divided into three groups: a sham control group (injection saline for four days); experiencing subcutaneous injection (2 g/kg BM per day, one each acetate); and pair-fed treatment...

10.3390/ani9100799 article EN cc-by Animals 2019-10-14

To explore the effect of selenium-enriched yeast (SeY) on intestinal barrier functions in weaned pigs upon oxidative stress, a <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mn>2</mml:mn><mml:mo>×</mml:mo><mml:mn>2</mml:mn></mml:math> factorial design was utilized and thirty-two were randomly assigned into four groups. Pigs with or without exposure to stress (diquat challenge) fed basal diet SeY-containing diet. The trial lasted for 21 days, result showed that SeY...

10.1155/2020/5490743 article EN Oxidative Medicine and Cellular Longevity 2020-03-19

An experiment was conducted to investigate the effects of dietary energy level on performance and immune function stressed broiler chickens (Gallus gallus domesticus). A total 96 three-day-old male (Ross × Ross) were divided into two groups. One group received a high (HE) diet other low (LE) for 7 days. At 5 days age, from each further sub-groups one following treatments 3 days: (1) subcutaneous injection corticosterone, twice per day (CORT group; 2 mg CORT/kg BW in corn oil) (2) oil,...

10.1371/journal.pone.0119750 article EN cc-by PLoS ONE 2015-03-24

The pro-apoptotic Bax and Bak proteins are considered central to apoptosis, yet apoptosis occurs in their absence. Here, we asked whether the mitochondrial protein VDAC1 mediates independently of Bax/Bak. Upon screening a fungal secondary metabolite library for compounds inducing Bax/Bak-deficient mouse embryonic fibroblasts, identified cyathin-R, new cyathane diterpenoid compound able activate absence Bax/Bak via promotion oligomerization that cytochrome c release....

10.1074/jbc.m115.648774 article EN cc-by Journal of Biological Chemistry 2015-08-08

The present study was conducted to investigate the effect of copper supplementation on lipid metabolism in rabbits. Our showed dietary addition (5-45 mg/kg) increased body mass gain, but decreased fat and liver weights compared with those control group (P < 0.05). Copper (45 significantly skeletal muscle weight, inhibited cytoplasmic accumulation liver, adipose tissue Compared group, plasma triglyceride levels very low density lipoprotein treatment gene expression carnitine...

10.1080/16546628.2017.1348866 article EN cc-by Food & Nutrition Research 2017-01-01

This study aimed to investigate the effects of different acute high ambient temperatures on redox status in liver broilers. A total 144 35-day-old Arbor Acres broilers were randomly divided into 4 groups with 6 replicates birds each and subsequently distributed environment chambers for heat stress. The temperature set 26°C (control), 29°C, 32°C, 35°C h, respectively. Various indicators tested evaluate hepatic status. Then, hallmarks hepatocellular antioxidant apoptosis measured by qRT-PCR...

10.1016/j.psj.2020.05.019 article EN cc-by-nc-nd Poultry Science 2020-06-20

Copper serves as a co-factor for host of metalloenzymes, particularly cytochrome c oxidase (COX). Although it is known that impaired COX function can lead to the excessive accumulation reactive oxygen species (ROS), mechanisms underlying how copper depletion leads cell damage are poorly understood. Here, we have investigated role during ferroptosis. The bathocuproinedisulfonic (BCS) treatment depolarized mitochondrial membrane potential, increased total cellular ROS levels, stimulated...

10.3390/antiox11112084 article EN cc-by Antioxidants 2022-10-22

Summary Silicon oxide and sodium silicate were investigated as potential agents for the control of postharvest pink rot in Chinese cantaloupe (cultivar Yujingxing) caused by Trichothecium roseum . In vitro tests showed that silicate, when added to potato dextrose agar, was effective suppressing radial growth pathogen on medium, whereas silicon ineffective. The effectiveness increased with concentration, fungus completely inhibited at 100 m When melons dipped solutions, both significantly ( P...

10.1111/j.1365-2621.2006.01464.x article EN International Journal of Food Science & Technology 2007-05-10

Glucocorticoids (GCs) induce profound hyperphagia in birds. However, the neuronal regulatory network underlying GC-provoked is unclear. To determine whether any cross talk occurs among hypothalamic GC receptors (GRs), AMP-activated protein kinase (AMPK), and GCs regulation of appetite, we performed an intracerebroventricular injection mifepristone (a GR inhibitor) compound C (an AMPK on GC-treated male chicks. The results indicate that central administration increased expression neuropeptide...

10.1210/en.2013-1632 article EN Endocrinology 2014-04-02

Background and Purpose Increasing evidence has suggested cadmium (Cd), as an inducer of ROS, is a potential pathogenic factor in human neurodegenerative diseases. Thus, it important to find effective interventions for Cd‐induced oxidative stress the CNS. Here, we have studied effects celastrol, plant‐derived triterpene, on ROS production cell death neuronal cells, induced by Cd. Experimental Approach PC12, SH‐SY5Y cells primary murine neurons were used study celastrol neuroprotection against...

10.1111/bph.13655 article EN British Journal of Pharmacology 2016-10-20

Flavonoids have been reported to exhibit prooxidant cytotoxicity against cancer cells, but the underlying mechanism is still poorly understood. Here we investigated potential that p53-inducible gene 3 (PIG3), a NADPH:quinone oxidoreductase, mediated of flavonoids on human hepatoma HepG2 cells. The results showed (apigenin, luteolin, kaempferol, and quercetin) inhibited growth cells in dosage- time-dependent manner, induced morphological changes characteristic apoptosis We also found...

10.1039/c5fo00142k article EN Food & Function 2015-01-01

The present study was conducted to investigate the effect of Artemisia argyi on production performance and intestinal barrier rabbits. Weaned Hyla rabbits (30 d, n = 160) similar body weight were divided into 4 groups (40 per treatment), they fed a control diet or an experimental supplemented with 3%, 6%, 9% A. argyi. results showed that dietary supplementation did not affect rabbits' food intake gain regardless inclusion level but decreased diarrhea rate index (P < 0.05). Dietary addition...

10.1093/jas/skz047 article EN Journal of Animal Science 2019-02-06

This study elucidated the function role of dietary selenium-enriched yeast (SeY) supplementation on growth performance, immune function, and antioxidant capacity in weaned pigs exposure to oxidative stress. Thirty-two similarity weight were randomly divided into four treatments: (1) nonchallenged control, (2) control+SeY, (3) control+diquat, (4) control+SeY+diquat. The period experiment was 21 days; day 16, injected with diquat or sterile saline. Results revealed that stress notably...

10.1155/2021/5533210 article EN cc-by BioMed Research International 2021-03-27

This study was conducted to investigate the impacts of chlorogenic acid (CGA) on growth performance, intestinal permeability, digestion and absorption-related enzyme activities, immune responses, antioxidant capacity cecum microbial composition in weaned rabbits. One hundred sixty rabbits were allotted four treatment groups fed with a basal diet or supplemented 400, 800, 1,600 mg/kg CGA, respectively. After 35-d trial, 800 CGA-supplemented group had higher (p < 0.05) ADG lower F/G than those...

10.3389/fmicb.2022.1027101 article EN cc-by Frontiers in Microbiology 2022-11-07
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