A5101587390- Advanced Glycation End Products research
- Geophysics and Sensor Technology
- Pulsars and Gravitational Waves Research
- Optical Imaging and Spectroscopy Techniques
- Liver Disease Diagnosis and Treatment
- Cold Atom Physics and Bose-Einstein Condensates
- Natural Antidiabetic Agents Studies
- Infrared Thermography in Medicine
- Atomic and Subatomic Physics Research
- Astronomical Observations and Instrumentation
- Adaptive optics and wavefront sensing
- Lung Cancer Treatments and Mutations
- Wireless Networks and Protocols
- Hepatocellular Carcinoma Treatment and Prognosis
- Metabolomics and Mass Spectrometry Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Advanced Frequency and Time Standards
- Photoacoustic and Ultrasonic Imaging
- Advancements in Battery Materials
- Thermoregulation and physiological responses
- IPv6, Mobility, Handover, Networks, Security
- MRI in cancer diagnosis
- Ultrasound and Hyperthermia Applications
- Neurological Disorders and Treatments
- Skin Protection and Aging
Shandong Agricultural University
2025
Anhui Academy of Medical Sciences
2025
Shanghai Jiao Tong University
2022-2024
Ruijin Hospital
2022-2024
Hefei Institutes of Physical Science
2017-2024
University of Chinese Academy of Sciences
2018-2024
Central South University
2022-2024
Chinese Academy of Sciences
2010-2024
Anhui Institute of Optics and Fine Mechanics
2009-2024
Anhui Agricultural University
2024
Abstract Objectives The capability of MR elastography (MRE) to differentiate fibrosis and inflammation, provide precise diagnoses is crucial, whereas the coexistence inflammation may obscure diagnostic accuracy. Methods In this retrospective study, from June 2020 December 2022, chronic viral hepatitis patients who underwent multifrequency MRE (mMRE) were included in, further divided into, training validation cohorts. hepatic viscoelastic parameters [shear wave speed ( c ) loss angle φ...
This study aimed to explore the added value of viscoelasticity measured by magnetic resonance elastography (MRE) in prediction Ki-67 expression hepatocellular carcinoma (HCC) using a deep learning combined radiomics (DLCR) model. retrospective included 108 histopathology-proven HCC patients (93 males; age, 59.6 ± 11.0 years) who underwent preoperative MRI and MR elastography. They were divided into training (n = 87; 61.0 9.8 testing 21; 60.6 10.1 cohorts. An independent validation cohort...
With the wide application of AI technology, AIGC is gradually establishing its core position in field intelligent design. Its powerful data processing and pattern recognition capabilities provide more reliable diverse decision support for design process. In industrial equipment design, Stable Diffusion has significant advantages as an tool. order to further explore potential automobile appearance optimize process, this paper proposes a set innovative generative methods based on assistance...
In recent years, outbreak of the novel duck reovirus (NDRV) disease has occurred frequently in populations. Due to its rapid spreading, absence effective control methods, and high treatment costs, NDRV caused huge losses waterfowl breeding China. As reported, four non-structural (NS) proteins are encoded by genome, among which σNS protein is an RNA-binding that can improve stability bound RNA forming oligomers (Adams Cory, 1998). Nevertheless, mechanism it facilitates replication remains...
This study aims to investigate how different wound microenvironmental factors (temperature, pH, and osmotic pressure) influence the autofluorescence of Staphylococcus aureus (S. aureus) its underlying molecular mechanisms, specifically focusing on porphobilinogen synthase gene (hemB) expression. We measured average fluorescence intensity S. colonies under varying conditions pH (3, 5, 7, 9, 11), temperature (25°C, 31°C, 37°C, 43°C), pressure (0.9%, 1.8%, 2.7%, 3.6%) over time. Fluorescence...
Background Due to substantial comorbidities of major depressive disorder (MDD) and anxiety (AN), these two disorders must be distinguished. Accurate identification diagnosis facilitate effective prompt treatment. EEG biomarkers are a potential research hotspot for neuropsychiatric diseases. The purpose this study was investigate the differences in power spectrum at theta oscillations between patients with MDD AN. Methods Spectral analysis used 66 43 Participants wore 16-lead caps measure...
Background Pretreatment identification of microvascular invasion (MVI) in hepatocellular carcinoma (HCC) is important when selecting treatment strategies. Purpose To improve models for predicting MVI and recurrence‐free survival (RFS) by developing nomograms containing three‐dimensional (3D) MR elastography (MRE). Study Type Prospective. Population 188 patients with HCC, divided into a training cohort ( n = 150) validation 38). In the cohort, 106/150 completed 2‐year follow‐up. Field...
Elemicin, an alkenylbenzene constituent of natural oils several plant species, is widely distributed in food, dietary supplements, and medicinal plants. 1′-Hydroxylation known to cause metabolic activation alkenylbenzenes leading their potential toxicity. The aim this study was explore the relationship between elemicin metabolism its toxicity through comparing maps 1′-hydroxyelemicin. Elemicin transformed into a reactive metabolite 1′-hydroxyelemicin, which subsequently conjugated with...
Coumarins have aroused high interests due to their diverse bioactivities. Understanding of its metabolism contributes determine the druggability coumarin in vivo.A sensitive and efficient strategy based on ultra-performance liquid chromatography-mass spectrometer (UPLC-MS) analysis combined with various data-processing techniques including metabolomics multiple mass defect filter (MMDF) was established for comprehensive screening elucidation potential metabolites.Total 20 metabolites...
IEEE 802.11 is an economical and efficient standard that has been applied to vehicular networks. However, the long handoff latency of scheme for become important issue seamless roaming in environments, because more handoffs may be triggered due higher mobility vehicles. This paper presents a new fast location-based particularly designed environments. With position movement direction vehicle location information surrounding access points (APs), our protocol able accurately predict several APs...
To elucidate the metabolism of pazopanib, a metabolomics approach was performed based on ultra-performance liquid chromatography coupled with electrospray ionization quadrupole mass spectrometry. A total 22 pazopanib metabolites were identified in vitro and vivo. Among these metabolites, 17 novel, including several cysteine adducts aldehyde derivatives. By screening using recombinant CYPs, CYP3A4 CYP1A2 found to be main forms involved hydroxylation. Formation conjugate (M3), an derivative...
The use of ventilation air methane (VAM) has attracted more and attention in recent years. experimental investigation on homogeneous combustion fuel ultra-lean methane–air mixtures is carried out reactors packed with without a monolith. results show that the oxidation follows consecutive reaction scheme. In process, although little CH4 may be directly oxidized to CO2 at low temperatures, most CO as intermediate product then further high temperatures. present also presence monolith an obvious...
Background Different MR elastography (MRE) systems may produce different stiffness measurements, making direct comparison difficult in multi‐center investigations. Purpose To assess the repeatability and reproducibility of liver measured by three typical MRE systems. Study Type Prospective. Population/Phantoms Thirty volunteers without disease history (20 males, aged 21–28)/5 gel phantoms. Field Strength/Sequence 3.0 T United Imaging Healthcare (UIH), 1.5 Siemens Healthcare, General Electric...
Time-restricted eating (TRE) has been shown to extent lifespans in drosophila and mouse models by affecting metabolic anti-inflammatory activities. However, the effect of TRE on human immune system, especially immunosenescence, intestinal microbiome, metabolism remains unclear. We conducted a 30-day 16:8 single-arm clinical trial with 49 participants. Participants consumed daily meals from 9 a.m. 5 p.m., provided nutrition canteen balanced, calorie-appropriate nutrition, which is designed...
Myristicin is widely distributed in spices and medicinal plants. The aim of this study was to explore the role metabolic activation myristicin its potential toxicity through a metabolomic approach. myristicin–N-acetylcysteine adduct identified by comparing maps 1′-hydroxymyristicin. supplement N-acetylcysteine could protect against cytotoxicity 1′-hydroxymyristicin primary mouse hepatocytes. When depletion intracellular pretreated with diethyl maleate hepatocytes, induced deteriorated. It...