A5003461719- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- HIV/AIDS Research and Interventions
- Infectious Diseases and Tuberculosis
- Pneumonia and Respiratory Infections
- Global Maternal and Child Health
- Adolescent Sexual and Reproductive Health
- HIV Research and Treatment
- Public Health Policies and Education
- Salmonella and Campylobacter epidemiology
- Hepatitis B Virus Studies
- Fatigue and fracture mechanics
- Advanced Machining and Optimization Techniques
- Syphilis Diagnosis and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Ethics in Clinical Research
- Advanced machining processes and optimization
- HIV-related health complications and treatments
- Diagnosis and treatment of tuberculosis
- HIV, Drug Use, Sexual Risk
- Global Health and Surgery
- Health Policy Implementation Science
Clinton Health Access Initiative
2016-2020
Columbia University
2014
National Health Laboratory Service
2008-2013
University of the Witwatersrand
2008-2013
There is robust clinical evidence to support offering early access antiretroviral treatment (ART) all HIV-positive individuals, irrespective of disease stage, both improve patient health outcomes and reduce HIV incidence. However, as the global guidelines shift meet this evidence, it still largely unknown if ART for (also referred "treatment prevention" or "universal test treat") a feasible intervention in resource-limited countries where approach could have biggest impact on course...
Numerous reports have documented isolated transmission events or clonal outbreaks of multidrug-resistant Mycobacterium tuberculosis strains, but knowledge their epidemic spread remains limited. In this study, we evaluated drug resistance, strain diversity, and clustering rates in patients diagnosed with (MDR) (TB) at the National Health Laboratory Service (NHLS) Central TB Johannesburg, South Africa, between March 2004 December 2007. Phenotypic susceptibility testing was done using indirect...
Genotyping of multidrug-resistant (MDR) Mycobacterium tuberculosis strains isolated from (TB) patients in four South African provinces (Western Cape, Eastern KwaZulu-Natal, and Gauteng) revealed a distinct population structure the MDR all regions, despite evidence substantial human migration between these settings. In analyzed provinces, negative correlation strain diversity an increasing level drug resistance (from MDR-TB to extensively drug-resistant TB [XDR-TB]) was observed. Strains...
ABSTRACT Fourth-generation HIV rapid tests (RTs) claim to detect both p24 antigen (Ag) and antibodies (Ab) for early identification of acute infections, important targeting prevention reducing transmission. In a nationally representative household survey in Swaziland, 18,172 adults, age 18 49 years, received home-based testing 2010 2011. Of the individuals, 5,822 (32.0%) were Ab positive (Ab + ) by Determine HIV-1/2 Ab/Ab combo test, 5,789 (99.4%) those confirmed be reactive Uni-Gold test....
Engaging communities in community-based health research is increasingly being adopted low- and middle-income countries. The use of community advisory boards (CABs) one method practicing involvement research. To date, few studies provide in-depth accounts the strategies that CAB members to practice engagement. We assessed perspectives, experiences practices first local Eswatini (formerly known as Swaziland), which was implemented part MaxART Early Access ART for All study. Trained Swazi...