- Transcranial Magnetic Stimulation Studies
- Neural and Behavioral Psychology Studies
- EEG and Brain-Computer Interfaces
- Attention Deficit Hyperactivity Disorder
- Migraine and Headache Studies
- Functional Brain Connectivity Studies
- Muscle activation and electromyography studies
- Child and Adolescent Psychosocial and Emotional Development
- Neurological disorders and treatments
- Nutrition, Genetics, and Disease
- Maternal Mental Health During Pregnancy and Postpartum
- Infant Development and Preterm Care
- Advanced MRI Techniques and Applications
- Digital Mental Health Interventions
- Neuroscience and Neural Engineering
- Neural dynamics and brain function
- Child Development and Digital Technology
- Family Support in Illness
- BRCA gene mutations in cancer
- Obsessive-Compulsive Spectrum Disorders
- Autism Spectrum Disorder Research
- Posttraumatic Stress Disorder Research
- Behavioral and Psychological Studies
- Pediatric Pain Management Techniques
- Autoimmune Neurological Disorders and Treatments
Evangelisches Krankenhaus Bielefeld
2019-2025
RWTH Aachen University
2024-2025
Bielefeld University
2022-2024
Westfälische Hochschule
2024
University of Lübeck
2017-2020
University Hospital Schleswig-Holstein
2017-2020
Kiel University
1999-2019
Goethe University Frankfurt
2014
University of Göttingen
2002-2005
Sechenov University
1999
Purpose of review Noninvasive brain stimulation (NIBS) is a promising method for altering cortical excitability with clinical implications. It has been increasingly used in children, especially neurodevelopmental disorders. Yet, its safety and applications the developing require further investigation. This aims to provide an overview commonly NIBS techniques including transcranial electrical (tES) magnetic (TMS). Safety data other methods not reported this review. Recent findings In line...
Importance Transcranial direct current stimulation (tDCS) has the potential to be a sustainable treatment option in pediatric attention-deficit/hyperactivity disorder (ADHD), but rigorously controlled multicenter clinical trials using state-of-the-art techniques are lacking. Objectives To determine effect sizes of changes cognitive and measures assess safety tolerability course optimized multichannel tDCS over prefrontal target regions ADHD. Design, Setting, Participants In sham-controlled,...
Heart rate variability has been found to be related emotional processing and responses. Studies that investigated these relationships were mostly lab-based or cross-sectional. Only limited research used intensive longitudinal data, in particular investigating within-individual processes real-life settings. This study addresses the applicability of ambulatory-assessed electrocardiograms combination with experience sampling methodology by associations various HRV measures affective states on...
Photosensitivity or photoparoxysmal response (PPR) is a highly heritable electroencephalographic trait characterized by an abnormal cortical to intermittent photic stimulation (IPS). In PPR-positive individuals, IPS induces spikes, spike-waves slow waves. The PPR may be restricted posterior visual areas (i.e. local with occipital spikes only) spread anterior non-visual regions propagation). mechanisms underlying the and causing its remain clarified. unmedicated individuals PPR-negative...
Psychological factors are important in the chronification and aggravation of headaches. We studied 90 patients suffering from migraine, chronic daily headache (CDH) evolved episodic or tension-type (TTH). Emotional, cognitive, behavioral pain coping were assessed using Kiel Pain Inventory (KPI), Beck's Depression Inventory, State-Trait-Anxiety Quality Life Questionnaire. In addition, clinical course was analyzed a validated diary. The results as follows. Firstly, KPI is reliable internally...
Attention deficit hyperactivity disorder (ADHD) is one of the most frequent disorders in children and adolescents. Although ADHD can be effectively treated with psychostimulants, a significant proportion patients discontinue treatment because adverse events or insufficient improvement symptoms. In addition, cognitive abilities which are frequently impaired ADHD, not directly targeted by medication. Therefore, additional options, especially to improve abilities, needed. Because its relatively...
Abstract Methodological studies investigating transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex (lDLPFC) in paediatric populations are limited. Therefore, we investigated a population whether success of multichannel tDCS lDLPFC depends on concurrent task performance and individual head anatomy. In randomised, sham-controlled, double-blind crossover study 22 healthy participants (10–17 years) received 2 mA anodal (atDCS) with without 2-back working...
Zusammenfassung: Tic-Störungen, Zwangsstörungen und die Aufmerksamkeitsdefizit-Hyperaktivitätsstörung (ADHS) sind oft mit Impulskontrolldefiziten aggressivem Verhalten verbunden. Auf epidemiologischer, psychopathologischer neurobiologischer Ebene besteht eine enge Nachbarschaft von Tic-Störungen Zwangsstörungen; ADHS Zwangsphänomene scheinen dagegen zunächst eher gegensätzlicher Pole zu sein. Der diesbezügliche Forschungsstand zur klinischen Bedeutung assoziiertem zwanghaftem wird...
Abstract The concept of hypersensitivity in migraineurs was advanced mainly on the basis studies information processing which increased amplitudes and reduced habituation cortical evoked event related potentials were found migraine sufferers. present investigation examined whether exhibit within three different experimental paradigms various non electrocortical response parameters. Samples 24 migraine, 19 tension‐type headache sufferers, normal controls compared regarding their subjective...
Abstract Empathy is defined as the ability to vicariously experience others’ suffering (vicarious pain) or feeling their joy reward). While most neuroimaging studies have focused on vicarious pain and describe similar neural responses during observed personal negative affective involvement, only initial evidence has been reported for rewards positive empathy. Here, we propose a novel approach, based simultaneous recording of multi-subject EEG signals exploiting wavelet coherence...
Abstract Transcranial Direct Current Stimulation (tDCS) is a non-invasive neuromodulation technique with wide variety of clinical and research applications. As increasingly acknowledged, its effectiveness subject dependent, which may lead to time consuming cost ineffective treatment development phases. We propose the combination electroencephalography (EEG) unsupervised learning for stratification prediction individual responses tDCS. A randomized, sham-controlled, double-blind crossover...
Abstract Background Transcranial direct current stimulation (tDCS) is a brain technique currently being researched as an alternative or complimentary treatment for various neurological disorders. There little knowledge about experiences of the participants tDCS clinical research, especially from pediatric studies. Methods An interview study with typically developing minors (n = 19, mean age 13,66 years) participating in study, and their parents 18) was conducted to explore views inform...
Abstract We discuss an epileptic incident in undiagnosed 13-year old girl participating a clinical study investigating the effects of transcranial direct current stimulation (tDCS) healthy children and adolescents. This poses important research ethics questions with regard to design, especially pertaining screening gaining informed consent. Potential benefits problems also need be considered. The ethical analysis case presented this paper has been by in-depth interview conducted after child...