A5043175800- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- Diphtheria, Corynebacterium, and Tetanus
- Fetal and Pediatric Neurological Disorders
- MRI in cancer diagnosis
- Botulinum Toxin and Related Neurological Disorders
- Plant-based Medicinal Research
- Intramuscular injections and effects
- Schizophrenia research and treatment
- Bone and Joint Diseases
- Traumatic Brain Injury Research
- Silicon Nanostructures and Photoluminescence
- Bacterial Infections and Vaccines
- Dementia and Cognitive Impairment Research
- Tryptophan and brain disorders
- Autism Spectrum Disorder Research
- Semiconductor materials and devices
- Herpesvirus Infections and Treatments
- Nanowire Synthesis and Applications
- EEG and Brain-Computer Interfaces
- Posttraumatic Stress Disorder Research
- Neural dynamics and brain function
- Orthopedic Infections and Treatments
- Genetics and Neurodevelopmental Disorders
New York University
2016-2025
University School
2018-2022
NYU Langone Health
2016-2020
Advanced Imaging Research (United States)
2016
Columbia University Irving Medical Center
2009
University of Wisconsin–Madison
2003-2007
University of Utah
2001-2003
National Institute of Materials Physics
1998-2002
Abstract The diffusion tensor is currently the accepted model of in biological tissues. measured behavior may be more complex when two or distinct tissues with different tensors occupy same voxel. In this study, a partial volume MRI signal for diffusion‐tensor compartments presented. Simulations using demonstrate that conventional single could lead to highly variable and inaccurate measurements behavior. differences between two‐tensor models depend on orientations, fractions, exchange...
Abstract Diffusion tensor MRI provides unique directional diffusion information that can be used to estimate the patterns of white matter connectivity in human brain. In this study, behavior an algorithm for tractography is examined. The algorithm, called TEND, uses entire deflect estimated fiber trajectory. Simulations and imaging experiments on vivo brains were performed investigate algorithm. simulations show deflection term less sensitive than major eigenvector image noise. brain...
Transcranial magnetic stimulation (TMS) combined with high-density electroencephalography (EEG) can be used to directly examine the properties of thalamocortical circuits in brain without engaging an individual cognitive or motor tasks. The authors investigated EEG responses schizophrenia patients and healthy comparison subjects following application TMS premotor cortex.Sixteen 14 were recruited participate study. Participants underwent three five TMS/high-density sessions at various doses....
Abstract Structural brain change and concomitant cognitive decline are the seemingly unavoidable escorts of aging. Despite accumulating studies detailing effects age on cognition, relationship between white matter features function in aging have only recently received attention remain incompletely understood. White microstructure can be measured with diffusion tensor imaging (DTI), but whether DTI provide unique information that is not explained by volume known. In current study,...
Clinical overlap between autism spectrum disorder (ASD) and attention-deficit/hyperactivity (ADHD) is increasingly appreciated, but the underlying brain mechanisms remain unknown to date.To examine associations white matter organization 2 commonly co-occurring neurodevelopmental conditions, ASD ADHD, through both categorical dimensional approaches.This investigation was a cross-sectional diffusion tensor imaging (DTI) study at an outpatient academic clinical research center, Department of...
Background Brain alterations in structure and function have been identified people with risk factors for sporadic type Alzheimer's disease (AD), suggesting that can be detected decades before AD diagnosis. Although the effect of apolipoprotein E ( APOE ) ɛ4 on brain is well‐studied, less known about family history AD. We examined main effects integrity, addition to assessing possible additive these two factors. Methods Diffusion tensor imaging was performed 136 middle‐aged asymptomatic...
Abstract The Orientation Distribution Function (ODF) is used to describe the directionality of multimodal diffusion in regions with complex fiber architecture present brain and other biological tissues. In this study, an approximation for ODF water from diffusional kurtosis imaging (DKI) presented. DKI requires only a relatively limited number measurements and, brain, b values no higher than 2500 s/mm 2 . DKI‐based decomposed into two components representing Gaussian non‐Gaussian (NG)...
Diffusional kurtosis imaging is an extension of DTI but includes non-Gaussian diffusion effects, allowing more comprehensive characterization microstructural changes during brain development. Our purpose was to use diffusional measure age-related in both the WM and GM developing human brain.Diffusional performed 59 subjects ranging from birth 4 years 7 months age. Diffusion metrics, fractional anisotropy, mean were collected VOIs within multiple structures subsequently analyzed with respect...
Microstructural white matter deficits in Autism Spectrum Disorders (ASD) have been suggested by both histological findings and Diffusion Tensor Imaging (DTI) studies, which show reduced fractional anisotropy (FA) increased mean diffusivity (MD). However, imaging reports are generally not consistent across studies the underlying physiological causes of reported differences FA MD remain poorly understood. In this study, we sought to further characterize ASD employing an advanced diffusion...
Recurrent herpes simplex infections present distinct therapeutic problems which have led to various approaches treatment. At a recent national dermatologic meeting, it was suggested that favorable results followed vaccination using unmodified material taken directly from the primary active disease site. We no experience with this approach may be of value, but is attendant some danger as exemplified by following cases. Case1.—R. W., 22-year-old white man, first seen in 1952 after complaints...