A5075911413- Visual perception and processing mechanisms
- Neural dynamics and brain function
- Neuroscience and Neuropharmacology Research
- Neural and Behavioral Psychology Studies
- EEG and Brain-Computer Interfaces
- Attention Deficit Hyperactivity Disorder
- Structural Health Monitoring Techniques
- Functional Brain Connectivity Studies
- Neurogenesis and neuroplasticity mechanisms
- Gaze Tracking and Assistive Technology
- Advanced Memory and Neural Computing
- Vibration Control and Rheological Fluids
- Retinal Development and Disorders
- Neurobiology and Insect Physiology Research
- Face Recognition and Perception
- Neuroscience and Neural Engineering
- Axon Guidance and Neuronal Signaling
- Visual Attention and Saliency Detection
- Hydraulic and Pneumatic Systems
- Dementia and Cognitive Impairment Research
- Color Science and Applications
- Acoustic Wave Phenomena Research
- Vibration and Dynamic Analysis
- Neuroinflammation and Neurodegeneration Mechanisms
- Retinal Imaging and Analysis
Universitat de Barcelona
2015-2024
Institució Catalana de Recerca i Estudis Avançats
2015-2024
Sant Joan de Déu Research Foundation
2024
Red de Investigación en Actividades Preventivas y Promoción de la Salud
2024
Institut de Recerca Sant Joan de Déu
2022-2024
Hospital Sant Joan de Déu Barcelona
2016-2021
Instituto de Neurociencias
2019
GTx (United States)
2018
Graduate School Neurosciences Amsterdam Rotterdam
2001-2010
University of Amsterdam
1998-2005
The brain frequently needs to store information for short periods. In vision, this means that the perceptual correlate of a stimulus has be maintained temporally once been removed from visual scene. However, it is not known how system transfers sensory into memory component. Here, we identify neural working in monkey primary cortex (V1). We propose component may link activity with activity.
Neurons in the primary visual cortex (V1) receive feedforward input from thalamus, which shapes receptive-field properties. They additionally recurrent inputs via horizontal connections within V1 and feedback higher areas that are thought to be important for conscious perception. Here, we investigated what roles different glutamate receptors play conveying macaque V1. As a measure of processing, used figure-ground modulation (FGM), increased activity neurons representing figures compared...
Abstract We have analyzed the early development of main hippocampal afferents in mouse. Following injections lipophilic tracer 1–1′‐dioctadecyl‐3, 3, 3′, 3′‐tetramethylindocarbocyanine perchorate (DiI) entorhinal cortex, axons were observed for first time inthe hippocampus at E15, white matter, At E17, fibers arborized within stratum lacunosum‐moleculare. subsequent stages formed dense networks that restricted to their appropriate termination zone The invading fascia dentata noticed E19,...
During neural development, specific recognition molecules provide the cues necessary for formation of initial projection maps, which are reshaped later in development. In some systems, guiding axonal pathfinding and target selection provided by cells that present only at critical times. For instance, floor plate guides commissural axons spinal cord, subplate is involved thalamocortical connections. Here we study development entorhinal connections to murine hippocampus, adult terminate...
Abstract Immunocytochemical techniques were used to characterize the neuronal populations in hippocampal subplate and marginal zone from embryonic day 13 (E13) postnatal 5 (P5). Sections processed for visualization of microtubule‐associated protein 2 (MAP2) other antigens such as neurotransmitters, neuropeptides, calcium‐binding proteins a synaptic antigen (Mab SMI81). At E13–E14, only ventricular primitive plexiform layer recognized. Some cells later stratum displayed MAP2‐, γ‐aminobutyric...
Cortical neurons are generated within the proliferative layer and follow a strict 'inside-out' gradient of migration positioning, which determines characteristic layering pattern neural connections in adult cerebral cortex. Thus, directional postmitotic neuroblasts towards I regulation radial glia phenotype subserving cortical central issues corticogenesis. Recent studies showing that gene disrupted reeler mutation – reelin is expressed Cajal–Retzius cells have indicated role for these...
When stimulus information enters the visual cortex, it is rapidly processed for identification. However, sometimes processing of inadequate and subject fails to notice stimulus. Human psychophysical studies show that this occurs during states inattention or absent-mindedness. At a neurophysiological level, remains unclear what these are. To study role cortical state in perception, we analyzed neural activity monkey primary cortex before appearance We that, reported stimulus, was stronger...
Cajal-Retzius (CR) cells are transient, pioneer neurons of layer I the cortex that believed to play essential roles in corticogenesis, e.g., neuronal migration and synaptogenesis. Here we have used calretinin immunostaining study characteristics, survival, fate CR single organotypic slice cultures mouse neocortex hippocampus deprived their extrinsic afferents. In neocortical explants, were observed after 1-3 d vitro (DIV), but they disappeared 5-7 DIV, which is similar time degeneration...
We continuously scan the visual world via rapid or saccadic eye movements. Such movements are guided by information, and thus oculomotor structures that determine when where to look need information control To know whether areas contain activity may contribute of movements, we recorded neural responses in cortex monkeys engaged a delayed figure-ground detection task analyzed during period preparation. show ≈100 ms before onset visually memory-guided saccades V1 becomes stronger strongest...
Objective: ADHD youth show poor oculomotor control. Recent research shows that attention-related eye vergence is weak in children. Method: To validate as a marker to classify ADHD, we assessed the modulation angle of children ( n = 43) previously diagnosed with while performing an attention task and compared results age-matched clinical controls 19) healthy peers 30). Results: We observed strong responses participants controls. showed no significant responses. Machine-learning models...
To assess whether the eye-tracking approach of RECOGNeyes game has potential therapeutic benefits for children with neurodevelopmental disorders, in particular attention-deficit/hyperactivity disorder (ADHD). is a computer that played using eyes as controller. The rationale behind individuals ADHD have an underdeveloped attention control system. This system not because they lack this capacity but ability been sufficiently developed. was designed intervention training visual ADHD.The sample...
Figure-ground is the segmentation of visual information into objects and their surrounding backgrounds. Two main processes herein are boundary assignment surface segregation, which rely on integration global scene information. Recurrent processing either by intrinsic horizontal connections that connect neurons or feedback projections from higher areas provide such information, considered to be neural substrate for figure-ground segmentation. On contrary, a role feedforward in unknown. To...
Covert spatial attention produces biases in perceptual and neural responses the absence of overt orienting movements. The mechanism that gives rise to these effects is poorly understood. Here we report relation between fixational eye movements, namely vergence, covert attention. Visual stimuli modulate angle vergence as a function their ability capture This illustrates bottom-up In visual auditory cue/no-cue paradigms, greater cue condition than no-cue condition. shows top-down component....
Recent evidence shows a novel role for eye vergence in orienting attention adult subjects. Here we investigated whether such modulation by is present children and it altered with ADHD compared to control We therefore measured the angle of previously diagnosed while performing cue task results those from age-matched controls. observed strong group weak group. In addition, was different between informative uninformative condition. This difference less noticeable Our study supports observation...
Behavioral measures such as expectancy and attention have been associated with the strength of synchronous neural activity. On this basis, it is hypothesized that activity affects our ability to detect recognize visual objects. To investigate role in perception, we studied magnitude precision correlated activity, before after stimulus presentation within cortex (V1), relation a monkey's performance figure-ground discrimination task. We show during period transition synchronized occurs...