A5019028999- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Nutrition and Health in Aging
- Lipoproteins and Cardiovascular Health
- RNA modifications and cancer
- Body Composition Measurement Techniques
- Health Systems, Economic Evaluations, Quality of Life
- Health, psychology, and well-being
- Heavy Metal Exposure and Toxicity
- COVID-19 Pandemic Impacts
- Allergic Rhinitis and Sensitization
- Dermatology and Skin Diseases
- Bone health and osteoporosis research
- Cardiovascular Disease and Adiposity
- Cancer Immunotherapy and Biomarkers
- COVID-19 impact on air quality
- Musculoskeletal pain and rehabilitation
- Gestational Diabetes Research and Management
- Galectins and Cancer Biology
- Protease and Inhibitor Mechanisms
- Cardiovascular Health and Risk Factors
- Consumer Attitudes and Food Labeling
- Computational Drug Discovery Methods
- Renal cell carcinoma treatment
- Pesticide Exposure and Toxicity
Jilin University
2022-2025
Jilin Medical University
2024
Background: Overweight and obesity lead to a range of noncommunicable diseases (NCDs), such as type 2 diabetes, cardiovascular disease, stroke. Physical activity (PA) is an important lifestyle behavior for controlling body weight. Dietary inflammatory index (DII), which associated with systemic markers, used evaluate the potential dietary inflammation. This first study investigate independent joint associations PA DII risk overweight/obesity among US adults.
The association of plasma metals on the risk cardiovascular diseases (CVD) in adults with prediabetes remains poorly investigated. To assess between metal exposure and CVD prediabetic United States using five metals. Five cycles data (2011–2012, 2013–2014, 2015–2016, 2017–2018) from NHANES were adopted this study. measured 1088 participants prediabetes. We utilized multivariate logistic regression, WQS, BKMR models to evaluate associations CVD. found link 2nd quartile, 3rd 4th quartiles...
Proliferative hepatocellular carcinomas (HCCs) is a class of aggressive tumors with poor prognosis. We aimed to construct computed tomography (CT)-based radiomics nomogram predict proliferative HCC, stratify clinical outcomes and explore the tumor microenvironment.
Skin cutaneous melanoma (SKCM) is the most lethal form of skin cancers owing to high invasiveness and metastatic potential. Tumor microenvironment (TME) provides powerful evidences for discerning SKCM, raising prospect identify biomarkers SKCM. Based on transcriptome profiles patients with SKCM corresponding clinical information from The Cancer Genome Atlas (TCGA), we used ESTIMATE algorithm calculate ImmuneScore StromalScore identified TME-Related differentially expressed genes (DEGs), than...
Abstract Background Multimorbidity is defined as two or more chronic health conditions existing in an individual simultaneously. has been associated with poor conditions, such higher care costs and the quality of life. Thus, identifying risk factors multimorbidity required for prevention. Methods This study was based on Comprehensive Demonstration Research Project Major Chronic Noncommunicable Disease Prevention Control Technology Northeast China initiated by Medical University. The...
Depression substantially impacts on quality of life, personal relationships, and self-care. Gastrointestinal disorders are the common comorbidity depression 24.3% patients with have disordered bowel habits. Dietary intake live microbes alters host's microflora is beneficial for prevention control health depression. We aim to investigate association dietary further examine weather or mediates therapeutic effect microbes.
With the restriction of organophosphorus and other insecticides, pyrethroids are currently second most-used group insecticides worldwide due to their advantages such as effectiveness low toxicity for mammalian. Animal studies clinical case reports have documented associations between adverse health outcomesand exposure pyrethroids. At present, association chronic pyrethroid osteoarthritis (OA) remains elusive.Cross-sectional data from National Health Nutrition Examination Survey 1999-2002...
Tamoxifen (TAM) resistance is finally developed in over 40% of patients with estrogen receptor α-positive breast cancer (ERα
Background Smoking is a factor for hypertension. We aim to reveal novel plasma proteins mediating the relationship of smoking with hypertension and identify potential drug targets on basis Mendelian randomization design. Methods Results Data were selected from largest genome‐wide association study meta‐analysis performed by Genome‐Wide Association Study Sequencing Consortium Alcohol Nicotine Use. deCODE Health UK Biobank Pharma Proteomics Project. extracted FinnGen Study. Moreover,...
<title>Abstract</title> In present study, we explore the role of HIF-1α-regulated Galectin-3 in VM and poor prognosis HCC as well potential regulatory mechanism. Immunohistochemistry method was used to evaluate HIF-1α CD31/PAS expression patients. Vitro experiments were conducted reveal molecular mechanisms that regulate under hypoxia. Moreover, effects on biological function cells investigated using MTS kit, wound-healing assay, cell transwell flow cytometry assay three-dimensional culture...
Portal hypertension (PH) is the primary cause of severe complications associated with cirrhosis, such as hepatic encephalopathy, ascites, and gastroesophageal variceal bleeding. Measurement venous pressure gradient (HVPG) derived by subtracting free from wedged via catheterization right vein stands a well-established technique for assessing portal 1 . An HVPG equal to or exceeding 10 mm Hg denotes clinically significant (CSPH), serving pivotal parameter prognostication treatment response...
AbstractObjectiveSarcopenia is a disease with high global prevalence, but its causes are not well understood. In recent years, growing number of research shows serious effect environmental factors on the human body. We aim to investigate association urinary heavy metals sarcopenia risk, and further examine mediating aging in this association.MethodsThe study included 5790 participants used multivariate logistic regression, weighted quantization sum (WQS) Bayes kernel machine regression...
<sec> <title>UNSTRUCTURED</title> We aimed to explore whether the modality of body fat distributions after postpartum is feasible ascertain T2DM risk in women with a history GDM. Body was determined by Dual–energy X–ray absorptiometry (DXA) 442 GDM from National Health and Nutrition Examination Survey (NHANES) 2011–2018. The analyzed using 14 indices provided DXA. contribution risks evaluated multivariable logistic regression analysis. found that positively associated ratio A G, VATM, TATM,...
Abstract Introduction: A series of strategies adopted by the Chinese government can indeed control COVID-19 epidemic, but they also cause negative impact on people's mental health and economic incomes. How to balance relationship between epidemic prevention social development is an urgent topic for current research. Methods: We included 122 rebound events involved 96 cities caused Delta variant from May 21, 2021 February 23, 2022 corresponding 32 environmental factors. Principal Component...