A5090292585- Diabetes Treatment and Management
- Liver Disease Diagnosis and Treatment
- Allergic Rhinitis and Sensitization
- Diet, Metabolism, and Disease
- Metabolism, Diabetes, and Cancer
- Pharmacovigilance and Adverse Drug Reactions
- Asthma and respiratory diseases
- Sinusitis and nasal conditions
- Pancreatitis Pathology and Treatment
- Diabetes Management and Research
- Gastroesophageal reflux and treatments
- Gastrointestinal motility and disorders
- Multiple Myeloma Research and Treatments
- Helicobacter pylori-related gastroenterology studies
- Aldose Reductase and Taurine
- Pancreatic and Hepatic Oncology Research
- Pharmaceutical Practices and Patient Outcomes
- Alcohol Consumption and Health Effects
- Pancreatic function and diabetes
- Gastrointestinal disorders and treatments
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Lipid metabolism and biosynthesis
- Pharmaceutical studies and practices
- Drug-Induced Adverse Reactions
Gentofte Hospital
2023-2024
Copenhagen University Hospital
2023-2024
Zealand Pharma (Denmark)
2023-2024
Frederiksberg Hospital
2023-2024
Nordsjællands Hospital
2023
University of Copenhagen
2015-2023
Hvidovre Hospital
2017-2018
Rigshospitalet
2015-2016
Objectives: Chronic pancreatitis (CP) is a multifaceted disease associated with several risk factors and complex clinical presentation. We established the Scandinavian Baltic Pancreatic Club (SBPC) Database to characterise study natural history of CP in Northern European cohort. Here, we describe design database characteristics cohort.Methods: Nine centres from six different countries Scandinavian-Baltic region joined database. Patients definitive or probable (M-ANNHEIM diagnostic criteria)...
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common inflammatory disorder associated asthma. This association well described in patients CRSwNP undergoing endoscopic sinus surgery (ESS); however, some are never referred for surgery, and the frequency of asthma this group largely unknown. Objective To determine treated primary care (PC) setting who have been to compare ESS patients. Methods Fifty-seven had undergone were prospectively recruited from nine PC ear, nose,...
Modern healthcare requires clinicians to navigate through complex drug treatments. This review offers an overview of sources information which can be used for general medication prescription and challenging patient populations. Key considerations pregnant or breastfeeding patients, those with renal impairment, liver dysfunction are discussed. We also touch on adverse reactions interactions. Finally, about services from independent regional centers, that by clinicians, provided.
Aims Hyperglucagonaemia contributes to the pathophysiology in type 2 diabetes (T2D), but mechanisms behind inappropriate glucagon secretion are not fully understood. Glucagon and amino acids regulated a feedback loop referred as liver–α cell axis. Individuals with non-alcoholic fatty liver disease (NAFLD) appear be resistant, disrupting axis resulting hyperglucagonaemia hyperaminoacidaemia. We investigated associations between circulating glucagon, acids, fat content cohort of individuals...
The metabolic phenotype of totally pancreatectomised patients includes hyperaminoacidaemia and predisposition to hypoglycaemia hepatic lipid accumulation. We aimed investigate whether the loss pancreatic glucagon may be responsible for these changes.
N-acyl taurines (NATs) are bioactive lipids with emerging roles in glucose homeostasis and lipid metabolism. The acyl chains of hepatic biliary NATs enriched polyunsaturated fatty acids (PUFAs). Dietary supplementation a class PUFAs, the omega-3 acids, increases their cognate mice humans. However, synthesis pathway PUFA-containing remains undiscovered. Here, we report that human livers synthesize acyl-chain preference is similar murine liver homogenates. In mouse, found NAT synthase activity...
Summary This article examines five cases where unintended adverse reactions have led to new therapeutic outcomes. The cover subsequent applications of acetylsalicylic acid, sildenafil, thalidomide, domperidone, and disulfiram. These examples demonstrate the versatility drugs in addressing diverse medical challenges. discussion highlights importance analyzing drug identify opportunities arising from reactions.
Glucagon secretion and signaling are affected in several metabolic disorders including different types of diabetes. To understand these mechanisms better, we investigated the effect exogeneous glucagon participants deprived endogenous and/or insulin. We included nine middle-aged, normal-weight patients who had undergone total pancreatectomy (PX), eight with type 1 diabetes (T1D) healthy controls a randomized, double-blinded crossover study (groups were matched by age, gender BMI)....