A5036495830- Electrospun Nanofibers in Biomedical Applications
- Advanced Sensor and Energy Harvesting Materials
- RNA Interference and Gene Delivery
- Wound Healing and Treatments
- Advanced biosensing and bioanalysis techniques
- Planarian Biology and Electrostimulation
- Orthopaedic implants and arthroplasty
- Surgical Sutures and Adhesives
- Hemostasis and retained surgical items
- Neuroscience and Neural Engineering
- 3D Printing in Biomedical Research
- Gear and Bearing Dynamics Analysis
- Advanced machining processes and optimization
- Advanced Machining and Optimization Techniques
- Structural Health Monitoring Techniques
- Mesenchymal stem cell research
- Probabilistic and Robust Engineering Design
- Antimicrobial Peptides and Activities
- biodegradable polymer synthesis and properties
- Photochromic and Fluorescence Chemistry
- Conducting polymers and applications
- Bone Tissue Engineering Materials
- Photoreceptor and optogenetics research
- Muscle activation and electromyography studies
- Structural Response to Dynamic Loads
Shanghai Stomatological Hospital
2022-2025
Fudan University
2022-2025
Yangzhou University
2023-2024
Shanghai Jiao Tong University
2024
Hydrogels are emerging as the most promising dressings due to their excellent biocompatibility, extracellular matrix mimicking structure, and drug loading ability. However, existing hydrogel exhibit limited breathability, poor environmental adaptability, potential resistance, options, which extremely restrict therapeutic effect working scenarios. Here, current research introduces first paradigm of textile based on novel gelatin glycerin (glyhydrogel) fibers fabricated by Hofmeister wet...
Electrotherapy is a promising tissue repair technique. However, electrotherapy devices are frequently complex and must be placed adjacent to injured tissue, thereby limiting their clinical application. Here, we propose general strategy facilitate by modulating endogenous electric fields with nonadjacent (approximately 44 mm) wireless through 3D-printed entirely soft bioresorbable triboelectric nanogenerator based stimulator, without any electrical accessories, which has biomimetic mechanical...
Abstract The primary challenges posed by oral mucosal diseases are their high incidence and the difficulty in managing symptoms. Inspired ability of bioelectricity to activate cells, accelerate metabolism, enhance immunity, a conductive polyacrylamide/sodium alginate crosslinked hydrogel composite containing reduced graphene oxide (PAA‐SA@rGO) is developed. This possesses antibacterial, anti‐inflammatory, antioxidant properties, serving as bridge turn “short circuit” injured site into...
Conductive fibers are vital for next-generation wearable and implantable electronics. However, the mismatch of mechanical, electrical, biological properties between existing conductive human tissues significantly retards their further development. Here, concept neuro-like to meet these aforementioned requirements is proposed. A new wet spinning process established continuously produce pure gelatin hydrogel fibers. The key controllable rapid gelation solutions based on salting-out effect,...
Abstract Dental pulp regeneration is a promising strategy for addressing tooth disorders. Incorporating this involves the fundamental challenge of establishing functional vascular networks using dental stem cells (DPSCs) to support tissue regeneration. Current therapeutic approaches lack efficient and stable methods activating DPSCs. In study, we used chemically modified microRNA (miRNA)-loaded tetrahedral-framework nucleic acid nanostructure promote DPSC-mediated angiogenesis miR-126-3p...
Polyetheretherketone (PEEK) is a widely used engineering plastic in orthopedic and dental implants, but its bioinertness leads to poor bone integration. To overcome this, sulfonation treatment was applied PEEK first create rough, microporous surface enhancing cellular adherence Subsequently, amorphous magnesium phosphate (AMP) nanosheets were produced through microwave-assisted synthesis, hydroxyapatite (HA) generated using bionic solution hydrothermal method. A dual-layer coating system...
Abstract Oral mucosal injuries are commonly caused by factors such as trauma, infection, or inflammation, especially in diabetic patients where healing is difficult and significantly affects quality of life. In this study, a nanocarrier system based on DNA tetrahedrons (TDN) developed, which serve ideal vectors due to their excellent intracellular uptake drug delivery capabilities. By efficiently delivering miR132 into cells, the proliferation migration human oral fibroblasts (HOMFs)...
Abstract Dental pulp regeneration is a promising strategy for addressing tooth disorders. Incorporating this involves the fundamental challenge of establishing functional vascular networks using dental stem cells (DPSCs) to support tissue regeneration. Current therapeutic approaches lack efficient and stable methods activating DPSCs. In study, we used chemically modified microRNA (miRNA)-loaded tetrahedral-framework nucleic acid nanostructure promote DPSC-mediated angiogenesis miR-126-3p...
<title>Abstract</title> In order to achieve gear longitudinal modification and improve grinding efficiency, a novel methodology is proposed, the method of accurate control values given. The core principle that disc installed obliquely generated teeth, cubic boron nitride (CBN) sintered on disc. Firstly, expounded. Secondly, based this methodology, adjustment model established, it concluded can be accurately controlled by installation angle Finally, effectiveness in achieving whole teeth...
Abstract Over the past few decades, there have been advancements in development of high‐performance tissue adhesives as alternatives to traditional sutures and staples for rapid effective wound closure post‐surgery. While offer advantages such ease use, short application time, minimal damage, they also face challenges related biocompatibility, biodegradability, adhesive strength. In this study, L ‐lysine diisocyanate (LDI) trimethylolpropane (TMP) were utilized primary raw materials produce...
The sensitivity analysis model is frequently used to express the influence of conditional elements on structural reliability. However, traditional limited a few influencing factors, and has small scope application. In this paper, modified proposed by combining optimal polynomial response surface function with Sobol algorithm. And calculation approach was combined coupling factor test design, range verification, multi-body dynamics statics analysis, which enables achieve quantitative value...