- Wheat and Barley Genetics and Pathology
- Genetic Mapping and Diversity in Plants and Animals
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Aquaculture Nutrition and Growth
- Reproductive biology and impacts on aquatic species
- Aquaculture disease management and microbiota
- Genetics and Plant Breeding
- Plant nutrient uptake and metabolism
- Crop Yield and Soil Fertility
- Adipose Tissue and Metabolism
- Plant Molecular Biology Research
- Muscle metabolism and nutrition
- Invertebrate Immune Response Mechanisms
- Plant Disease Resistance and Genetics
- Photosynthetic Processes and Mechanisms
- Plant-Microbe Interactions and Immunity
- Exercise and Physiological Responses
- Plant Stress Responses and Tolerance
- Epigenetics and DNA Methylation
- Plant responses to elevated CO2
- Rice Cultivation and Yield Improvement
- Congenital heart defects research
- Crustacean biology and ecology
- RNA modifications and cancer
- Genetic diversity and population structure
Shandong Agricultural University
2016-2025
Ministry of Agriculture and Rural Affairs
2019-2025
Wuhan University
2005-2025
Inner Mongolia Agricultural University
2025
Affiliated Hospital of Southwest Medical University
2025
Capital Medical University
2022-2024
Shanghai Tenth People's Hospital
2022-2024
South China Sea Institute Of Oceanology
2019-2023
Institute of Oceanology
2019-2023
Chinese Academy of Sciences
2014-2023
In some fish species, high or low temperature can switch the sex determination mechanisms and induce reversal when gonads are undifferentiated. During this temperature-induced reversal, expressions of many genes altered. However, genome-wide DNA methylation changes in after treatment unclear. Herein, we compared global from control females (CF), males (CM), temperature-treated (TF), (IM) F8 family Nile tilapia (Oreochromis niloticus) using methylated immunoprecipitation sequencing. The level...
Maize rough dwarf disease (MRDD), caused by various species of the genus Fijivirus, threatens maize production worldwide. We previously identified a quantitative locus qMrdd1 conferring recessive resistance to one causal species, rice black-streaked virus (RBSDV). Here, we show that Rab GDP dissociation inhibitor alpha (RabGDIα) is host susceptibility factor for RBSDV. The viral P7-1 protein binds tightly exon-10 and C-terminal regions RabGDIα recruit it infection. Insertion helitron...
Quality traits in wheat (Triticum aestivum L.) were studied by quantitative trait locus (QTL) analysis a recombinant inbred line (RIL) population, set of 131 lines derived from Chuan 35050 × Shannong 483 cross (ChSh). Grains RILs assayed for 21 quality related to protein and starch. A total 35 putative QTLs 19 with single QTL explaining 7.99–40.52% phenotypic variations detected on 10 chromosomes, 1D, 2A, 2D, 3B, 3D, 5A, 6A, 6B, 6D, 7B. The additive effects 30 positive, contributed 35050,...
Phosphorus (P) efficiency (PE), which comprises phosphorus uptake (PupE) and utilization (PutE), is considered as one of the most important factors for crop yield. In present study, 11 seedling traits 13 maturity related to wheat PE morphology were investigated using a set recombinant inbred lines (RILs) derived from cross "TN 18 × LM 6," under hydroponic culture trials field at low P (LP) normal (NP) levels in two different years, respectively. The LP input reduced biomass, yield PupE...
For more than half a century glucagon has been used as critical care medicine in the treatment of life-threatening hypoglycemia. It is commercially supplied lyophilized powder intended to be solubilized dilute aqueous hydrochloric acid immediately prior administration. We have envisioned "ready-to-use" drug immediate and likely use. Through series iterative changes native sequence we identified analogs appreciably enhanced solubility at physiological pH, chemical stability suitable for...
Several studies have shown that external application of micromolar magnesium (Mg) can increase the resistance legumes to aluminum (Al) stress by enhancing Al-induced citrate exudation. However, exact mechanism underlying this regulation remains unknown. In study, physiological and molecular mechanisms which Mg enhances exudation alleviate Al toxicity were investigated in broad bean. Micromolar concentrations alleviated paralleled stimulation increased activity plasma membrane (PM) H+-ATPase....
Protein- and starch-related quality traits, which are quantitatively inherited significantly influenced by the environment, critical determinants of end-use wheat. We constructed a high-density genetic map containing 10,739 loci (5,399 unique loci) using set 184 recombinant inbred lines (RILs) derived from cross 'Tainong 18 × Linmai 6' (TL-RILs). In this study, quantitative trait (QTLs) analysis was used to examine control grain protein content, sedimentation value, farinograph parameters,...
Epidermal growth factor receptor (EGFR) is an essential target for cancer treatment. However, EGFR inhibitor erlotinib showed limited clinical benefit in pancreatic therapy. Here, we the underlying mechanism of tumor microenvironment suppressing sensitivity through stellate cell (PSC). The expression alpha-smooth muscle actin (α-SMA) and hypoxia marker human tissues were detected by immunohistochemistry, their correlation with overall survival was evaluated. Human immortalized PSC...
With the continuous change of global climate, frequency low-temperature stress (LTS) in spring increased greatly, which led to increase wheat yield decline. The effects LTS at booting on grain starch synthesis and were examined two varieties with differing sensitivities (insensitive variety Yannong 19 sensitive Wanmai 52). A combination potted field planting was employed. For treatment booting, plants placed a climate chamber for 24 h −2°C, 0°C or 2°C from 19:00 07:00 then 5°C 19:00. They...
Phosphite (Phi), the reduced form of phosphate (Pi), is characterized by its stability, high solubility, efficient transport, resistance to fixation in soil, and widespread occurrence natural environments. Although Phi exhibits greater suitability than Pi as a soil fertilizer, it cannot be metabolized plants. In agricultural applications, serves bio-stimulant, fungicide, herbicide, has other purposes. As been shown promote plant growth, enhance stress resistance, improve fruit quality....
Low temperatures (LT) in spring can have a major impact on the yields of wheat winter. Wheat varieties with different cold sensitivities (the cold-tolerant Yannong 19 variety and cold-sensitive Yangmai 18 variety) were used to study responses grain starch synthesis dry material accumulation short-term LT during booting stage. The effects activities key enzymes, content dry-matter determined by exposing simulated from −2 2°C. Short-term stress caused decrease fullness grains along decreased...