A5006223903- Marine Ecology and Invasive Species
- Olfactory and Sensory Function Studies
- Zebrafish Biomedical Research Applications
- Ichthyology and Marine Biology
- Subterranean biodiversity and taxonomy
- Marine Invertebrate Physiology and Ecology
- Neurobiology and Insect Physiology Research
- Developmental Biology and Gene Regulation
- Animal Genetics and Reproduction
- Genetic diversity and population structure
- Genomics and Phylogenetic Studies
- Neurogenesis and neuroplasticity mechanisms
- Hippo pathway signaling and YAP/TAZ
- Cellular Mechanics and Interactions
- Photochromic and Fluorescence Chemistry
- Fish biology, ecology, and behavior
- Axon Guidance and Neuronal Signaling
- Turtle Biology and Conservation
- Oral and Maxillofacial Pathology
- Surgical Sutures and Adhesives
- Marine animal studies overview
- Congenital heart defects research
- Science, Research, and Medicine
- Marine Toxins and Detection Methods
- Angiogenesis and VEGF in Cancer
Centre National de la Recherche Scientifique
2009-2024
Institut de Biologie Paris-Seine
2018-2024
Sorbonne Université
2008-2024
Centre National pour la Recherche Scientifique et Technique (CNRST)
2023-2024
Laboratoire de Biologie du Développement
2020
Laboratoire de Neurobiologie Cellulaire et Moléculaire
2008-2011
Georgia Institute of Technology
2011
Abstract Jellyfish (medusae) are a distinctive life-cycle stage of medusozoan cnidarians. They major marine predators, with integrated neurosensory, muscular and organ systems. The genetic foundations this complex form largely unknown. We report the draft genome hydrozoan jellyfish Clytia hemisphaerica use multiple transcriptomes to determine gene across stages. Medusa, planula larva polyp each characterized by distinct transcriptome signatures reflecting abrupt transitions all deploy...
The cavefish morph of the Mexican tetra (Astyanax mexicanus) is blind at adult stage, although an eye that includes a retina and lens develops during embryogenesis. There are, however, two major defects in development. One apoptosis, phenomenon indirectly linked to expansion ventral midline sonic hedgehog (Shh) expression gastrulation induces degeneration. other lack quadrant retina. Here, we show such ventralisation not extended entire forebrain because fibroblast growth factor 8 (Fgf8),...
Every model species requires its own developmental table. Astyanax mexicanus, a teleost fish comprising both sighted river and blind cave populations, is becoming more important in the field of evolutionary biology. As such, staging table increasingly necessary, particularly since comparative analysis early events widely employed by researchers. We collected freshly spawned embryos from surface Pachón cavefish populations. Embryos were imaged every 10–12 min during first day development,...
The subterranean environment is often described as "extreme" and food poor. Laboratory experiments have shown that blind Mexican tetra Astyanax mexicanus (De Filippi, 1853) cavefish are better at finding in the dark than surface fish. Several morphological behavioural attributes could foster this obvious adaptive response to cave environments been described. Nonetheless, it currently unknown what young actually eat their natural environment. Our results from Pachón México during dry rainy...
Abstract Background Metamorphosis in marine species is characterized by profound changes at the ecophysiological, morphological, and cellular levels. The cnidarian Clytia hemisphaerica exhibits a triphasic life cycle that includes planula larva, colonial polyp, sexually reproductive medusa. Most studies so far have focused on embryogenesis of this species, whereas its metamorphosis has been only partially studied. Results We investigated main morphological larva during metamorphosis,...
One of the goals evolutionary developmental biology is to link specific adaptations changes in pathways. The dentition cypriniform fishes, which contrast many other teleost fish species possess pharyngeal teeth but lack oral teeth, provides a suitable model study development feeding adaptations. Here, we have examined involvement retinoic acid (RA) tooth and show that RA specifically required induce program zebrafish. Perturbation signaling at this stage abolished induction without affecting...
The larvae of the fish Astyanax mexicanus transiently develop a flat and adhesive structure on top their heads that we have called “the casquette” (cas, meaning “hat”). We hypothesized cas may be teleostean homolog well-studied Xenopus cement gland, despite different positions structures. Here show has an ectodermal origin, secretes mucus, expresses bone morphogenic protein 4 ( Bmp4 ) pituitary homeobox 1/2 Pitx1/2 ), is innervated by trigeminal ganglion serotonergic raphe neurons, role in...
Abstract Lake Malawi cichlid fishes exhibit extensive divergence in form and function built from a relatively small number of genetic changes. We compared the genomes rock- sand-dwelling species asked which variants differed among groups. found that 96% differentiated reside non-coding sequence but these diverged are evolutionarily conserved. Genome regions near enriched for craniofacial, neural behavioral categories. Following leads genome sequence, we used vs. sand-species their hybrids to...
Jellyfish (medusae) are a distinctive life-cycle stage of medusozoan cnidarians. They major marine predators, with integrated neurosensory, muscular and organ systems. The genetic foundations this complex form largely unknown. We report the draft genome hydrozoan jellyfish Clytia hemisphaerica use multiple transcriptomes to determine gene across stages. Medusa, planula larva polyp each characterised by distinct transcriptome signatures reflecting abrupt life cycle transitions, all deploy...
The larvae of aquatic vertebrates sometimes possess a transient, mucus-secreting gland on their heads. most studied these organs is the Xenopus cement gland. tadpoles use it to attach plants or water surface, supposedly hide from predators and save energy before they can swim feed. Moreover gland, being innervated by trigeminal fibres, also mediates locomotor stopping response when encounter an obstacle. We have described equivalent organ head teleost Astyanax mexicanus, that we called...
Despite recent progress, the complex roles played by extracellular matrix in development and disease are still far from being fully understood. Here, we took advantage of zebrafish sly mutation which affects Laminin γ1, a major component basement membranes, to explore its role olfactory system. Following detailed characterisation distribution developing circuit, analysed membrane integrity, placode brain morphogenesis, axon mutants, using combination immunochemistry, electron microscopy...
Despite recent progress, the complex roles played by extracellular matrix in development and disease are still far from being fully understood. Here, we took advantage of zebrafish sly mutation which affects Laminin γ1, a major component basement membranes, to explore its role olfactory system. Following detailed characterisation distribution developing circuit, analysed membrane integrity, placode brain morphogenesis, axon mutants, using combination immunochemistry, electron microscopy...
Abstract While the chemical signals guiding neuronal migration and axon elongation have been extensively studied, influence of mechanical cues on these processes remains poorly studied in vivo . Here, we investigate how forces exerted by surrounding tissues steer movements extension during morphogenesis olfactory placode zebrafish. We mainly focus contribution adjacent eye tissue, which develops underneath through extensive evagination invagination movements. Using quantitative analysis cell...
Despite recent progress, the complex roles played by extracellular matrix in development and disease are still far from being fully understood. Here, we took advantage of zebrafish
Despite recent progress, the complex roles played by extracellular matrix in development and disease are still far from being fully understood. Here, we took advantage of zebrafish sly mutation which affects Laminin γ1, a major component basement membranes, to explore its role olfactory system. Following detailed characterisation distribution developing circuit, analysed membrane integrity, placode brain morphogenesis, axon mutants, using combination immunochemistry, electron microscopy...