A5085149263- Diet, Metabolism, and Disease
- Inflammatory Biomarkers in Disease Prognosis
- Diabetes Treatment and Management
- Helicobacter pylori-related gastroenterology studies
- Adipose Tissue and Metabolism
- Biomarkers in Disease Mechanisms
- Veterinary medicine and infectious diseases
- Dietary Effects on Health
- Diet and metabolism studies
- Chronic Kidney Disease and Diabetes
- Mycobacterium research and diagnosis
- Acute Ischemic Stroke Management
- Lipoproteins and Cardiovascular Health
- Cardiovascular Disease and Adiposity
- Metabolism and Genetic Disorders
- Muscle metabolism and nutrition
- Pancreatitis Pathology and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
Fujian Medical University
2022-2025
First Affiliated Hospital of Fujian Medical University
2022-2025
Xiangya Hospital Central South University
2024
Central South University
2024
Fudan University
2022
Renal osteodystrophy is commonly seen in patients with chronic kidney disease (CKD) due to disrupted mineral homeostasis. Given the impaired renal function these patients, common anti-resorptive agents, including bisphosphonates, must be used caution or even contraindicated. Therefore, an alternative therapy without burden combat urgently needed. Here, we report that clinically relevant aerobic exercise significantly prevents high-turnover CKD mouse and compromising function....
Introduction Helicobacter pylori (H.pylori, Hp) affects billions of people worldwide. However, the emerging resistance Hp to antibiotics challenges effectiveness current treatments. Investigating genotype-phenotype connection for using next-generation sequencing could enhance our understanding this resistance. Methods In study, we analyzed 52 strains collected from various hospitals. The susceptibility these five was assessed agar dilution assay. Whole-genome then performed screen...
Chemotherapy-induced thrombocytopenia (CIT) is a severe complication in patients with cancer that can lead to impaired therapeutic outcome and survival. Clinically, options for CIT are limited by adverse effects high economic burdens. Here, we demonstrate ketogenic diets alleviate both animals humans without causing thrombocytosis. Mechanistically, diet-induced circulating β-hydroxybutyrate (β-OHB) increased histone H3 acetylation bone marrow megakaryocytes. Gain- loss-of-function...
The association between triglyceride-glucose (TyG) index and poor prognosis remains controversial. Whether renal function status affects the ability of TyG to predict has not yet been elucidated merits further studies.This retrospective cohort study included 22,031 participants from communities in U.S. By juxtaposing categories with estimated glomerular filtration rate (eGFR, either < 60 mL/min/1.73m2 or ≥ mL/min/1.73m2), were categorized into four distinct groups: (1) TyG_L/eGFR_H; (2)...
Studies have shown that in hypertensive patients, chronic kidney disease (CKD) is associated with a poor prognosis. Inflammation highly important factor the progression of CKD. Detecting systemic inflammation and intervening promptly patients hypertension may help reduce risk The inflammatory response index (SIRI) tool used to measure response, but its relationship CKD remains uncertain.