This study aims to propose a refinement of the current WRF-BEM . To achieve this goal, WRF experiments were conducted over Xi'an City, and results compared observations from 25 meteorological stations. The total simulation errors decomposed into sum of"LCZ type mismatch error"which caused by limitation horizontal model resolution, and"physical scheme error"due neglect dynamic-thermal effects urban vegetation. For"LCZ error", it was proved that could be eliminated increasing LCZ match rate...

Radiotherapy (RT) continues to encounter significant obstacles such as formidable resistance, potential harm adjacent healthy cells, and restricted effectiveness against tumors, resulting in a notable recurrence rate. Therefore, combining imaging, other treatments, suitable enzyme activity one nanoplatform can enhance the RT effect reduce damage normal tissue. In this study, integrating hafnium Prussian blue (PB) nanoparticles (PB NPs) provided innovative hafnium-doped PB (HPB) NPs...

Abstract Alleviating the urban heat island effect is of great significance to improve thermal comfort, energy saving and carbon reduction, realize sustainable development. At present, several methods are developed investigate effect, including meteorological observation data analysis, mesoscale WRF numerical simulation remote sensing image etc. Among them, widely used in comparative study different development periods. The local climate zone theory (LCZs), proposed by Stewart Oke (Bull Am...

Via immunomagnetic reduction assay, bio-molecules can be quantitatively detected with the aid of bio-functionalized magnetic nanoparticles, which are used as labeling markers for specific bio-molecules. To achieve an ultra-high sensitivity in detection bio-molecules, superconducting quantum interference device (SQUID) looks very promising a sensor signal that related to concentration We had developed single channel SQUID-based magnetosusceptometer, but increasing through-put, we have...

By specifically bio-functionalizing magnetic nanoparticles, nanoparticles are able to label target bio-molecules. This property can be applied quantitatively detect molecules invitro by measuring the related signals of bound with molecules. One is reduction in mixed-frequency ac susceptibility suspended due molecule-particle association. Many experimental results show empirically that molecular-concentration dependent follows logistic function. In this study, it has been demonstrated...

Abstract Water bodies are regarded as effective tools to improve urban thermal environment. However, there is little information regarding the impacts of water under different climatic conditions. In this study, effects similar were investigated in a temperate monsoon climate city (Xi’an) and humid subtropical (Chengdu) summer. Results showed that both reduced air temperature increase humidity their vicinity, closer body more obvious effects. Xi’an could provide cooling its surroundings all...

With the increasing importance of SQUID-based magnetically labeled immunoassay, study on synthesis controllable sizes magnetic nanoparticles plays a role to promote accuracy immunoassay. In this work, Fe/sub 3/O/sub 4/ nano-particles coated with suitable bio-probe (biotin) are synthesized through chemical co-precipitation process probe bio-target (avidin). Through developed here, particle hydrodynamic diameter can be adjusted from 30 90 nm, which provide candidates for probing various...

Magnetic nanoparticles biofunctionalized with antibodies are useful for specifically labeling target biomolecules. By measuring magnetic signals after the association between and biomolecules, concentration of biomolecules can be quantitatively detected. One methodologies is so-called immunomagnetic reduction (IMR), in which ac susceptibility reagent a function In this letter, relationship signal explored. According to experimental results on various kinds such as proteins chemicals, scaled...

The HTS superconducting quantum interference devices (SQUID) magnetometers meets the requirement for early-stage or hard-to-detect in-vitro diagnosis because of its ultrahigh sensitivity. For example, demand assaying ultra-low-concentration biomarkers tumors is always existing. It would be better to quantitatively detect vascular endothelial growth factor (VEGF) at concentration 1 pg/ml diagnosing malignancy. In this work, by using SQUID-based ac magnetosusceptometer and biofunctionalized...

The low limit of detection (LLD) plays an important role in biomolecular assays, especially for early-stage assays. Biomolecular detections usually involve the use two main elements: a reagent and analyzer, which both greatly contribute to LLD. In this work, relationships among LLD reagent-related factors are investigated. to-be-detected biomolecule is c-reactive protein (CRP) as example. assay method immunomagnetic reduction (IMR). components Fe(3)O(4) magnetic nanoparticles...

Although magnetic nanoparticles (MNPs) have been widely applied to animals in biomedicine, MNPs within should be examined real time, vivo, and without bio-damaged possibility evaluate whether the bio-function of is valid or further controls biomedicinal process because accompanying complex problems such as distribution biodegradation. The non-invasive high-sensitivity scanning detection using ac susceptometry based on a high-Tc superconducting quantum interference device (SQUID) presented....

Immunomagnetic reduction assay is used to quantitatively detect bio-molecules. Many reports show that the to-be-detected bio-molecular concentration dependent in alternative-current (ac) magnetic susceptibility of a reagent governed by logistic function, which four-parameter function. One parameters relates increase rate signal when bio-molecules increased. Theoretically, this parameter attributed clustering associations between and labeling particles reagent. In an immunomagnetic assay,...

To image magnetic nanoparticles (MNPs) on animal bodies, physicians often use resonance imaging to determine the superparamagnetic characteristics of MNPs during preoperative analysis. However, is unsuitable for other biomedical applications, such as curative surgical resection tumors or pharmacokinetic studies MNPs, because requirement nonmetal environments and high financial cost frequent examination, respectively. Thus, researchers have proposed nonmagnetic technologies, fluorescence,...

Nanomagnetically labeled immunoassays have been demonstrated to be promisingly applied in clinical diagnosis. In this work, by using antibody‐functionalized magnetic nanoparticles and a high‐temperature superconducting quantum interference device ac magnetosusceptometer, the assay properties for vascular endothelial growth factor (VEGF) serum are investigated. By utilizing method so‐called immunomagnetic reduction, of assaying VEGF explored. addition, concentrations samples normal people...

In order to understand the epidemic trends of influenza virus infection in Taiwan, 5,882 throat-swab specimens were collected from June 1979 1995. Influenza was detected 313 including samples at Taichung and Tainan 1981 1982. Among them, 214 isolates (68.4%) identified as type A, 99 (31.6%) B. course surveillance, strain A/Taiwan 1/86 (H1N1), known a world-wide reference strain, isolated April 1986. throughout year Taiwan based on frequency detection virus. Some strains referred intermediate...

To determine the iron concentration of administrated magnetic nano-particles in animals is essential for evaluation arrival efficiency target regions biomagnetism studies. In this work, a high T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</sub> superconucting quantum interference devices (SQUID) biosusceptometry with scanning coil set developed. The measurement principal based on AC susceptibility nano-particles, and low noise 8 pT/√Hz at...