A5101730439- Ion channel regulation and function
- COVID-19 epidemiological studies
- Pressure Ulcer Prevention and Management
- Diabetic Foot Ulcer Assessment and Management
- Cardiac electrophysiology and arrhythmias
- Travel-related health issues
- RNA modifications and cancer
- COVID-19 Pandemic Impacts
- Phytochemicals and Antioxidant Activities
- Growth Hormone and Insulin-like Growth Factors
- Drug-Induced Hepatotoxicity and Protection
- Asthma and respiratory diseases
- Cancer Mechanisms and Therapy
- Vascular Procedures and Complications
- Heart Rate Variability and Autonomic Control
- Antiplatelet Therapy and Cardiovascular Diseases
- Coronary Interventions and Diagnostics
- Inflammatory mediators and NSAID effects
- Total Knee Arthroplasty Outcomes
- Neuroscience and Neuropharmacology Research
- Balance, Gait, and Falls Prevention
- Advanced Glycation End Products research
- Spinal Cord Injury Research
- Genomics, phytochemicals, and oxidative stress
- Bone and Joint Diseases
Fujian Medical University
2010-2025
Shanghai Sunshine Rehabilitation Center
2022-2025
Tongji University
2021-2022
I-Shou University
2022
Shanghai University of Traditional Chinese Medicine
2022
Huazhong University of Science and Technology
2015-2021
Soochow University
2014-2020
Chang Bing Show Chwan Memorial Hospital
2020
Kaohsiung Medical University
2013-2020
University of Benin
2020
Radiotherapy (RT) continues to encounter significant obstacles such as formidable resistance, potential harm adjacent healthy cells, and restricted effectiveness against tumors, resulting in a notable recurrence rate. Therefore, combining imaging, other treatments, suitable enzyme activity one nanoplatform can enhance the RT effect reduce damage normal tissue. In this study, integrating hafnium Prussian blue (PB) nanoparticles (PB NPs) provided innovative hafnium-doped PB (HPB) NPs...
Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide. P21-activated kinase 4 (PAK4) and miR-9-5p have emerged as attractive therapeutic targets in several tumor types, but CRC, the regulation their biological function target association remain unclear.The expression PAK4 CRC tissues was determined using quantitative real-time PCR immunohistochemistry analyses. The targeted between predicted confirmed with bioinformatics analysis dual-luciferase reporter assay....
Plumbagin, a natural bicyclic naphthoquinone, has diverse pharmacological properties and biological benefits against number of disorders, including liver disease. Though plumbagin's hepatoprotective potential attracts attention, currently no experimental evidence exists on its effectiveness cholestatic injury. The present study investigated hepatoprotection in the rat model extrahepatic cholestasis using Bile Duct Ligation (BDL). We found that daily plumbagin supplementation protected from...
18β-Glycyrrhetinic acid is a nutraceutical agent with promising hepatoprotective effects. Its protective mechanisms against cholestatic liver injury were further investigated in rodent model of extrahepatic cholestasis caused by Bile Duct Ligation (BDL) rats. The daily oral administration improved histology, serum biochemicals, ductular reaction, oxidative stress, inflammation, apoptosis, impaired autophagy, and fibrosis. alleviated the BDL-induced hepatic systemic retention bile acids,...
Liquid extracts from pomegranate peel have the potential for use as natural antioxidant products. This study investigates quality changes of liquid before and after thermal treatment during sterilization storage. were prepared, sterilized under ultra-high temperature (UHT) at 121 °C 10 s then stored three temperatures (4, 25 37 °C) up to 180 days. The industrial, color, UV-visible spectrum profile (phenolics) characteristics measured.Thermal had no negative effects on spectral extracts....
Abstract Objectives This study aimed to evaluate prognostic value of quantitative flow ratio (QFR) in drug‐coated balloon (DCB) angioplasty for in‐stent restenosis (ISR). Background There is a high incidence recurrent ISR after DCB angioplasty. QFR novel method fast computation fractional reserve the target vessel based on coronary angiography (QCA) and fluid dynamics algorithms. Methods Patients participating RESTORE China randomized trial were enrolled classified into group non‐recurrent...
Pituitary apoplexy is a rare complication of pituitary tumors. We report case 41-year-old female with acromegaly due to macroadenoma, who developed after thyrotropin-releasing hormone (TRH) 200 microgram intravenous injection stimulation test. Neither emergency computed tomography (CT) scans nor magnetic resonance imaging (MRI), performed 6 hours and 12 hours, respectively, the active episode, disclosed evidence acute hemorrhage or infarction. Two days later, mass, removed by transsphenoidal...
Iloprost, a stable prostaglandin I2 (PGI2) analog, can inhibit allergic inflammation in an ovalbumin (OVA)-induced asthma model via inhibition of airway dendritic cell (DC) function. However, the underlying mechanism PGI2 signaling-mediated immunosuppression remains unclear. This study explored whether iloprost-treated DCs suppress by promoting antigen-specific regulatory T (Treg) differentiation through PGI2-G-protein-coupled receptor (IP). We established lung using hydrogel biomaterial...
To determine the incidence, duration, risk factors, and clinical outcomes for ciliary detachment after pars plana vitrectomy (PPV).A total of 109 eyes 103 patients who underwent PPV various disease entities were included. Ultrasound biomicroscopy was applied to tomographic features body before 1, 3, 7 days surgery. All then examined once weekly 2 months. Demographic, preoperative, intraoperative, postoperative parameters evaluated assess their predictive value in formation postvitrectomy...
The GSTP1 gene plays an important role in detoxification of carcinogens. polymorphisms may alter the susceptibility urinary system cancer. Numerous studies have been performed to investigate association between Ile105Val (rs1695 A>G) polymorphism and cancer risk. Nevertheless, results remain controversial only prostate bladder are covered. We identified eligible from PubMed, Elsevier, three equivalent Chinese databases including National Knowledge Infrastructure, Wanfang, Weipu. Pooled odds...
During neonatal testis development, centrally located gonocytes migrate to basement membrane of the seminiferous cords, where physical contact with a niche established by Sertoli cells is essential for transition into spermatogonial stem (SSCs). To provide structural support and signaling stimuli gonocyte-to-SSC that occurs at specific location during finite phase, temporal-spatial establishment critical. date, factors guide establish initial cell remain largely unknown. Using cell-specific...
Spinal cord injury patients are prone to develop deep tissue (DTI) as they may spend half their time per day in sitting postures, which produce excessive load buttocks. However, the impact of fat thickness on biomechanical response buttock posture remained unclear. This study aimed investigate influence subcutaneous interface pressure and distribution seated humans. To achieve this goal, a 3-dimensional finite element model male was constructed contact rigid cushion evaluated against...