A5043233060- Neuroscience and Neuropharmacology Research
- Sleep and Wakefulness Research
- Electromagnetic Fields and Biological Effects
- Memory and Neural Mechanisms
- Biochemical effects in animals
- Linguistic Studies and Language Acquisition
- Heat shock proteins research
- Spanish Linguistics and Language Studies
- Circadian rhythm and melatonin
- Spaceflight effects on biology
- Cholinesterase and Neurodegenerative Diseases
- Mitochondrial Function and Pathology
- Magnetic and Electromagnetic Effects
- Genetics, Aging, and Longevity in Model Organisms
- Neurological Disease Mechanisms and Treatments
- Connexins and lens biology
- Alkaline Phosphatase Research Studies
- Heart Rate Variability and Autonomic Control
- DNA and Nucleic Acid Chemistry
- Neurogenesis and neuroplasticity mechanisms
- Sleep and related disorders
- Computational Drug Discovery Methods
- Second Language Learning and Teaching
- Neural dynamics and brain function
- EEG and Brain-Computer Interfaces
Universitat Autònoma de Barcelona
2020-2021
University of Perugia
1999-2017
Sapienza University of Rome
2010
Istituto Sperimentale per la Zootecnia
1996
University of Chieti-Pescara
1981
Using electroencephalographic methods, rats learning or not a two-way active avoidance task were found to differ significantly in the structure of sleep determined day before training. The main differences concerned (i) synchronized episodes followed by wakefulness, which longer and fewer rats; (ii) paradoxical episodes, rats. Significant correlations present between number and/or average duration wakefulness avoidances escapes scored training session. Power spectral analysis indicated that...
A new highly sensitive analytical method for determining gabapentin [1-(aminomethyl) cyclohexaneacetic acid; Neurontin] in serum using gas chromatography/tandem mass spectrometry (GC-MS/MS) was developed. GC-MS/MS applied to determine the levels of samples mice at 1 and 6 h after oral or intraperitoneal treatment (300 mg/kg). At h, concentrations drug were 4.02 +/- 0.42 4.32 0.28 microg/mL treated orally intraperitoneally, respectively. decreased by about 66% both groups. The method,...
Purpose: The question of whether exposure to extremely low frequency magnetic fields (ELF-MF), may contribute cerebral cancer and neurodegeneration is current interest. In this study we investigated ELF-MF (50 Hz-1 mT) harms DNA induces expression 70-kDa heat shock protein (hsp70).Materials methods: CD1 mice were exposed a MF for 1 or 7 days (15 h/day) sacrificed either at the end after 24 h. Unexposed sham-exposed used as controls. Mouse brains dissected into cortex-striatum, hippocampus...
The possibility that the inducible 72-kDa heat shock protein (hsp72) is involved in learning-related plasticity mechanisms was investigated two inbred strains of mice show spontaneous differences spatial learning performance as well an opposite reactivity to stress. Induction hsp72 after radial maze training measured by immunoblotting hippocampus C57BL/6 (C57) and DBA/2 (DBA) exposed or nonexposed chronic acoustic In agreement with previous studies, inter-strain were found nonstressed C57...
Background: Several animal models of cerebral ischemia have been developed to investigate both pathophysiology and pharmacological treatment. The aim this study was verify the prognostic value EEG power spectra analysis in a two-vessel plus hypotension rat model transient global ischemia. Methods: Spontaneously hypertensive rats (SHRs) Wistar Kyoto (WKYs) were subjected 20 min bilateral common carotid artery occlusion by sodium nitroprusside followed reperfusion for seven days. Sham-operated...
Purpose: To determine whether a dose-response relationship exists among exposure to extremely low frequency magnetic fields (ELF-MF) at different densities and 70-kDa heat shock protein (hsp70) expression DNA damage in mouse brain.Materials methods: Male CD1 mice were exposed ELF-MF (50 Hz; 0.1, 0.2, 1 or 2 mT) for 7 days (15 h/day) sacrificed either the end of after 24 h. Hsp70 was determined cerebral cortex-striatum, hippocampus cerebellum by real-time reverse-transcriptase polymerase...
GAMBELUNGHE, C., R. ROSSI, G. MARIUCCI, M. TANTUCCI, and V. AMBROSINI. Effects of light physical exercise on sleep regulation in rats. Med. Sci. Sports Exerc., Vol. 33, No. 1, 2001, pp. 57–60. Purpose: Acute is known to enhance slow-wave (SWS) reduce paradoxical (PS) humans. In this study, we examined the effects moderate Method: Young adult Wistar rats underwent a 4-h baseline electroencephalographic (EEG) recording session. The following day, they were induced walk (0.8 m·min-1) or run (4...