A5034348128- Carcinogens and Genotoxicity Assessment
- Air Quality and Health Impacts
- Electromagnetic Fields and Biological Effects
- Chemical Safety and Risk Management
- Safe Handling of Antineoplastic Drugs
- Occupational exposure and asthma
- Effects and risks of endocrine disrupting chemicals
- Magnetic and Electromagnetic Effects
- Pesticide Exposure and Toxicity
- Toxic Organic Pollutants Impact
- Chemical Analysis and Environmental Impact
- Phytochemicals and Medicinal Plants
- Phytochemicals and Antioxidant Activities
- Insect Resistance and Genetics
- Health, Environment, Cognitive Aging
- Genetically Modified Organisms Research
- Pesticide and Herbicide Environmental Studies
- Drug-Induced Hepatotoxicity and Protection
- Nutrition and Health in Aging
- Water Treatment and Disinfection
- Nutritional Studies and Diet
- Potato Plant Research
- Genomics, phytochemicals, and oxidative stress
- Essential Oils and Antimicrobial Activity
- Esophageal Cancer Research and Treatment
University of Perugia
2014-2024
University of Brescia
1993-1996
German Cancer Research Center
1993
Heidelberg University
1993
Propolis is a resinous mixture produced by honeybees which has been used since ancient times for its useful properties. However, chemical composition and bioactivity may vary, depending on the geographical area of origin type tree bees use collecting pollen. In this context, research aimed to investigate total phenolic content (using Folin-Ciocalteu assay) antioxidant capacity FRAP, DPPH, ABTS assays) three black poplar (Populus nigra L.) propolis (BPP) solutions (S1, S2, S3), as well...
The International Agency for Research on Cancer has classified several antineoplastic drugs in Group 1 (human carcinogens), among which chlorambucil, cyclophosphamide (CP) and tamoxifen, 2A (probable human cisplatin, etoposide, N-ethyl- N-methyl-N-nitrosourea, 2B (possible bleomycins, merphalan mitomycin C. widespread use of these mutagenic/carcinogenic the treatment cancer led to anxiety about possible genotoxic hazards medical personnel handling drugs. aim present study was evaluate work...
The present study was undertaken to evaluate, in the HepG2 human hepatoma cell line, vitro cytotoxic, genotoxic, and apoptotic activities of estragole (1), contained essential oil Foeniculum vulgare (fennel) suspected induce hepatic tumors susceptible strains mice. Toward this end, an MTT cytotoxicity assay, a trypan blue dye exclusion test, double-staining (acridine orange DAPI) fluorescence viability single-cell microgel-electrophoresis (comet) mitochondrial membrane potential (Δψm) DNA...
Olive mill wastewater (OMWW), with its high level of phenolic compounds, simultaneously represents a serious environmental challenge and great resource potential nutraceutical activities. To increase the knowledge OMWW's biological effects, an aim to developing food supplement, we performed chemical characterisation extract using Liquid Chromatography-Quadrupole Time-of-flight spectrometry (LC-QTOF) in vitro genotoxicity/antigenotoxicity assessment on HepaRG ™ cells. Chemical analysis...
In tunnel construction workers, occupational exposure to dust (alpha-quartz and other particles from blasting), gases (nitrogen dioxide, NO(2)), diesel exhausts, oil mist has been associated with lung function decline, induction of inflammatory reactions in the lungs release mediators that may influence blood coagulation, increased risk chronic obstructive pulmonary disease. The present molecular epidemiology study was designed evaluate whether indoor pollutants during road might result...
High levels of disinfection by-products (DBPs) are constantly found in drinking water distributed Sardinia, an Italian island with a tourist vocation and critical issues related to the supply. To reduce concentration trihalomethanes disinfectant use was changed – chlorine dioxide adopted instead hypochlorite. However, this caused appearance other DBPs (e.g., chlorites) population. Thus, monochloramine as secondary (associated primary disinfectant) evaluated four treatment plants supplied by...
(1) Background: Cynara cardunculus L. subsp. scolymus (L.) Hegi, popularly known as artichoke, is an herbaceous plant belonging to the Asteraceae family. Artichoke leaf extracts (ALEs) have been widely used in traditional medicine because of their hepatoprotective, cholagogic, hypoglycaemic, hypolipemic and antibacterial properties. ALEs are also recognized for antioxidative anti-inflammatory activities. In this study, we evaluated cytotoxic, genotoxic, apoptotic activities, well effect on...
Biological Effect Monitoring in Peripheral Blood Lymphocytes from Subjects Occupationally Exposed to Antineoplastic Drugs: Assessment of Micronuclei Frequency: Milena VILLARINI, et al . Department Medical‐Surgical Specialties and Public Health (Section Health), University Perugia, Italy— Objectives drugs (ANPDs) are widely used the treatment cancer some nonneoplastic diseases. However, most if not all these chemical agents generally nonselective and, along with tumor cells, normal cells may...