Giuseppe Mastrangelo

ORCID: 0000-0003-4204-045X
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About
Contact & Profiles
Research Areas
  • Occupational and environmental lung diseases
  • Air Quality and Health Impacts
  • Carcinogens and Genotoxicity Assessment
  • Occupational Health and Safety Research
  • Occupational exposure and asthma
  • Epigenetics and DNA Methylation
  • Indoor Air Quality and Microbial Exposure
  • SARS-CoV-2 and COVID-19 Research
  • Bladder and Urothelial Cancer Treatments
  • Maternal and Perinatal Health Interventions
  • Glutathione Transferases and Polymorphisms
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Employment and Welfare Studies
  • Health Systems, Economic Evaluations, Quality of Life
  • Climate Change and Health Impacts
  • Telomeres, Telomerase, and Senescence
  • Immunotherapy and Immune Responses
  • Workplace Health and Well-being
  • Global Maternal and Child Health
  • Economic and Financial Impacts of Cancer
  • Traffic and Road Safety
  • Health, Environment, Cognitive Aging
  • Genetic Associations and Epidemiology
  • Tattoo and Body Piercing Complications

University of Padua
2016-2025

Baqiyatallah University of Medical Sciences
2021

AULSS 2 Marca Trevigiana
2021

University of Modena and Reggio Emilia
2019

Creative Research Enterprises (United States)
2019

Regione del Veneto
2019

National Cancer Institute
2015

Cancer Genetics (United States)
2015

University College London
2015

Ospedale San Giuseppe
2014

The objectives of this study were to measure the incidence sarcomas, including viscerally sited tumors that are not reported in cancer statistics, and draw explanatory clues from a large reliable sarcoma data set.Cases sarcomas regardless primary site (except bone joints) collected during 2 years 3 European regions totaling approximately 26,000,000 person-years. sources used pathology reports hospital discharges forms. Diagnoses reviewed by expert pathologists classified according 2002 World...

10.1002/cncr.27555 article EN Cancer 2012-04-19

Background Five cancer cases over 7 years were reported in a small orthopaedic hospital where radiation protection practice was poor.

10.1093/occmed/kqi048 article EN Occupational Medicine 2005-09-01
Jonine D. Figueroa Yuanqing Ye Afshan Siddiq Montserrat García‐Closas Nilanjan Chatterjee and 87 more Ludmila Prokunina‐Olsson Victoria K. Cortessis Charles Kooperberg Olivier Cussenot Simone Benhamou Jennifer Prescott Stefano Porru Colin P. Dinney Núria Malats Dalsu Baris Mark P. Purdue Eric J. Jacobs Demetrius Albanes Zhaoming Wang Xiang Deng Charles C. Chung Wei Tang H. Bas Bueno‐de‐Mesquita Dimitrios Trichopoulos Börje Ljungberg Françoise Clavel‐Chapelon Elisabete Weiderpass Vittorio Krogh Miren Dorronsoro Ruth C. Travis Anne Tjønneland Paul Brenan Jenny Chang‐Claude Elio Ríboli David V. Conti Manuela Gago‐Dominguez Mariana C. Stern Malcolm C. Pike David Van Den Berg Jian‐Min Yuan Chancellor Hohensee Rebecca J. Rodabough Géraldine Cancel‐Tassin Morgan Rouprêt Éva Compérat Constance Chen Immaculata De Vivo Edward Giovannucci David J. Hunter Peter Kraft Sara Lindström Angela Carta Sofia Pavanello Cecilia Arici Giuseppe Mastrangelo Ashish M. Kamat Seth P. Lerner H. Barton Grossman Jie Lin Jian Gu Xia Pu Amy Hutchinson Laurie Burdette William Wheeler Manolis Kogevinas Adonina Tardón Consol Serra Alfredo Carrato Reina García-Closas Josep Lloreta Molly Schwenn Margaret R. Karagas Alison Johnson Alan R. Schned Karla Armenti GM Monawar Hosain Gerald L. Andriole Robert L. Grubb Amanda Black W. Ryan Diver Susan M. Gapstur Stephanie J. Weinstein Jarmo Virtamo C.A. Haiman Maria Teresa Landi Neil E. Caporaso Joseph F. Fraumeni Paolo Vineis Xifeng Wu Debra T. Silverman Stephen J. Chanock Nathaniel Rothman

Candidate gene and genome-wide association studies (GWAS) have identified 11 independent susceptibility loci associated with bladder cancer risk. To discover additional risk variants, we conducted a new GWAS of 2422 cases 5751 controls, followed by meta-analysis two independently published GWAS, resulting in combined analysis 6911 814 controls European descent. TaqMan genotyping 13 promising single nucleotide polymorphisms P < 1 × 10−5 was pursued follow-up set 801 1307 controls. Two...

10.1093/hmg/ddt519 article EN public-domain Human Molecular Genetics 2013-10-24

Numerous studies have investigated mortality during a heatwave, while few quantified heat associated morbidity. Our aim was to investigate the relationship between hospital admissions and intensity, duration timing of heatwave across summer months. The study area (Veneto Region, Italy) holds 4577408 inhabitants (on January 1st, 2003), is subdivided in seven provinces with 60 hospitals about 20000 beds for acute care. Five consecutive heatwaves (three or more days Humidex above 40°C) occurred...

10.1186/1471-2458-7-200 article EN cc-by BMC Public Health 2007-08-09

Cancer is a significant and growing problem worldwide. While this increase may, in part, be attributed to increasing longevity, improved case notifications risk-enhancing lifestyle (such as smoking, diet obesity), hygiene-related factors resulting immuno-regulatory failure may also play major role call for revision of vaccination strategies protect against range cancers addition infections. Human endogenous retroviruses (HERVs) are component wider family retroelements that constitutes part...

10.1186/1471-2407-13-4 article EN cc-by BMC Cancer 2013-01-03

Abstract Background Aging represents a serious health and socioeconomic concern for our society. However, not all people age in the same way air pollution has been shown to largely impact this process. We explored whether polycyclic aromatic hydrocarbons (PAHs), excellent fossil wood burning tracers, accelerate biological aging detected by lymphocytes DNA methylation (DNAmAge) telomere length (TL), early nuclear (nDNA) hallmarks of non-mitotic mitotic cellular aging, mitochondrial copy...

10.1186/s12940-023-00975-y article EN cc-by Environmental Health 2023-03-17

Hepatocellular carcinoma (HCC) and liver cirrhosis (LC) are not well-established vinyl chloride monomer (VCM)-induced diseases. Our aim was to appraise the role of VCM, alcohol intake, viral hepatitis infection, their interactions, in etiology HCC LC. Thirteen cases 40 LC were separately compared with 139 referents without chronic diseases or cancer a case-referent study nested cohort 1,658 VCM workers. The odds ratios (ORs) 95% confidence intervals (CIs) estimated by common methods fitting...

10.1289/ehp.6972 article EN public-domain Environmental Health Perspectives 2004-05-27

Although the management of sarcoma is improving, non adherence to clinical practice guidelines (CPGs) remains high, mainly because low incidence disease and variety histological subtypes. Since little known about health economics sarcoma, we undertook a cost-effectiveness analysis (within CONnective TIssue CAncer NETwork, CONTICANET) comparing costs outcomes when clinicians adhered CPGs they did not. Patients studied had diagnosis were older than 15 years, been treated in Rhône-Alpes region...

10.1186/1472-6963-12-82 article EN cc-by BMC Health Services Research 2012-03-28

Bladder cancer is a complex disease with known environmental and genetic risk factors. We performed genome-wide interaction study (GWAS) of smoking bladder based on primary scan data from 3002 cases 4411 controls the National Cancer Institute GWAS. Alternative methods were used to evaluate both additive multiplicative interactions between individual single nucleotide polymorphisms (SNPs) exposure. SNPs P values < 5 × 10−5 evaluated further in an independent dataset 2422 5751 controls....

10.1093/carcin/bgu064 article EN Carcinogenesis 2014-03-24

This survey aimed at estimating the concentration of hair mercury (Hg) in fishermen and workers fish industry Marano Lagunare (North-eastern Italy, Upper Adriatic Sea). A field investigation was conducted from 2nd December 2023 through 18th April 2024, on 73 local fishermen, 83 93 controls among residents (mainly farmers/herdsmen) Dolomites Alps. An amount approximately 100 mg collected all respondents, who were also asked to fill out a self-administered questionnaire collecting...

10.1016/j.scitotenv.2024.178039 article EN cc-by-nc-nd The Science of The Total Environment 2025-02-01

To evaluate the frequency of micronucleated lymphocytes in a normal population, 45 healthy subjects were analysed by using modified cytochalasin B block method; influence some confounding factors (sex, age, smoking, etc.) taken into account. Using stepwise regression test smoking habits found to have statistically significant on cells and micronuclei. In addition, mitotic proliferative indexes, lymphocytes, at different culture times, studied four subjects. Based results we suggest that be...

10.1093/mutage/6.2.123 article EN Mutagenesis 1991-01-01

The administration of anesthetics determines depression the central nervous system and general anesthesia by inhalation may cause an environmental pollution operating rooms. It therefore conceive a possible occupational etiology Parkinson's Disease (PD). In Caucasian male aged 59 years, PD was diagnosed brain scans with presynaptic radioactive tracer dopaminergic system. Family history negative for disease or essential tremor. He smoker, moderate consumer coffee alcohol, never exposed to...

10.1186/1471-2377-13-194 article EN cc-by BMC Neurology 2013-12-01

Identifying a single disease as the underlying cause of death (UCOD) is an oversimplification clinical-pathological process leading to death. The multiple causes (MCOD) approach examines any mention in certificates. Taking diabetes example, study investigates: patterns certification, differences mortality figures based on UCOD and MCOD, factors associated certificates, potential MCOD analysis association between chronic diseases.The whole archive Veneto Region-Italy was extracted from 2008...

10.1186/s12963-015-0056-y article EN cc-by Population Health Metrics 2015-08-24

Abstract Although there is no evidence that elevated rates of cesarean sections (CS) translate into reduced maternal/child perinatal morbidity or mortality, CS have been increasingly overused almost everywhere, both in high and low-income countries. The primary section (PCS) has become a major driver the overall (OCS) rate, since it carries intrinsic risk repeat (RCS) future pregnancies. In our study we examined patterns PCS, planned PCS (PPCS), vaginal birth after 1 previous (VBAC-1)...

10.1038/s41598-019-57037-y article EN cc-by Scientific Reports 2020-01-15
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