A5103037613- Phagocytosis and Immune Regulation
- Immunotherapy and Immune Responses
- Cancer Immunotherapy and Biomarkers
- Head and Neck Cancer Studies
- Tracheal and airway disorders
- Endometrial and Cervical Cancer Treatments
- Advanced Radiotherapy Techniques
- Dysphagia Assessment and Management
- Ovarian cancer diagnosis and treatment
- Intraperitoneal and Appendiceal Malignancies
- Peroxisome Proliferator-Activated Receptors
- Fish Biology and Ecology Studies
- Atherosclerosis and Cardiovascular Diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- BRCA gene mutations in cancer
- Pancreatic and Hepatic Oncology Research
- Lung Cancer Diagnosis and Treatment
- Platelet Disorders and Treatments
- Nanoplatforms for cancer theranostics
- Male Breast Health Studies
- Extracellular vesicles in disease
- Social and Economic Development in India
- Gastrointestinal Bleeding Diagnosis and Treatment
- Cancer Risks and Factors
- Aquatic Ecosystems and Biodiversity
King George's Medical University
2019-2024
Birla Institute of Technology and Science, Pilani
2020
Cognizant (India)
2018
National Center for Biotechnology Information
2017
University of Pennsylvania
2010-2016
Royal Sussex County Hospital
2015
University of Michigan
2009-2013
Cleveland State University
2007-2011
Cleveland Clinic
2007-2011
Frenchay Hospital
2009
CD36 is a scavenger receptor that binds multiple ligands, including phosphatidyl serine (PS). Although CD36– mice do not have bleeding diathesis, we show here they significantly prolonged thrombotic occlusion times in response to FeCl3-induced vascular injury. Because cell-derived microparticles (MPs) are generated injury and circulate patients with prothrombotic diseases, hypothesized PS exposed on their surfaces could be an endogenous ligand transmits activating signal platelets. We found...
It has been speculated that IL-1 genes play a crucial role in the genetic predisposition to duodenal ulcer upon H. pylori infection by modulating host immune response. In present study, 310 individuals from Eastern India were subjected case-control study determine IL1B and IL1RN risk genotypes mediated ulcer. An analysis of genotype frequency revealed significantly higher -511TT (NT_022135.14:g.2302610C>T), OR=4.22 (95% CI=1.8-9.4) -31CC (NT_022135.14:g.2302130C>T), OR=2.16 CI 1.12-4.15)...
The aim of this study was to analyse the outcome laparoscopic management large bowel obstruction (LBO).A prospective electronic database (April 2001-June 2009) used identify outcomes in consecutive patients presenting with LBO.Twenty-four (13 male) median age 68 years (range 56-92 years), ASA grade I (2), II (6), III (14) and IV underwent surgery for LBO secondary cancer (21) diverticulosis (3). Supervised trainees performed four operations. Operations included anterior resection (10),...
Anatomical variations in head and neck cancer during IMRT leads to volume shrinkage, results dosimetric tumour normal tissue including parotid glands, with a risk of radiation toxicities.30 patients stage II-IV squamous cell carcinoma (HNSCC) were treated definitive IMRT-SIB concomitant chemotherapy. Volumetric evaluated the period by recalculating obtaining dose-volume histograms re-contoured target volumes glands on repeat CT scans taken multiple times treatment (CT1, CT2, CT3 CT4).Result...
Background: In the year 2014, Android smartphones accounted for one-third of mobile connections globally but are predicted to increase two-thirds by 2020. developing countries, where teleconsultations can benefit health-care providers most, ratio is even higher. This study compared use two phones, an 8 megapixel (MP) and a 16 MP phone, capturing microscopic images. Method: The phones were used capture images videos gastrointestinal biopsy teaching set referred cases from Armed Forces...
Intra-cavitary brachytherapy is an integral component of cervical cancer management, and uterine perforation the most significant complication, which may lead to prolonged overall treatment time decreased local control in these patients.A retrospective analysis patients who completed radiotherapy (external beam brachytherapy) our department was conducted determine incidence, effect on time, final outcome with during procedure.Among 55 women, 398 applications, 85 (21.36%) resulted...
Background: In cervical cancer treatment, overall treatment time (OTT) is an important prognostic factor. This study compares the clinical outcomes when High-Dose-Rate Intracavitary-Brachytherapy(HDR-ICRT) interdigitated with external beam radiotherapy(EBRT) versus sequential HDR-ICRT after EBRT in of locally advanced carcinoma cervix. Methods: Histologically confirmed cervix patients [FIGO Stage IIB–IVA (except IIIC-2)] were included and randomized into two groups. The group received 50Gy...
Objective: Dosimetric sparing of critical swallowing structures like constrictor muscles and larynx can lead to improved functional outcomes in head neck cancer patients treated by chemoradiation. Methods: A total 50 Patients with newly diagnosed, biopsy proven AJCC stage II–IV squamous cell cancers (HNSCC) were prospectively studied. 25 randomized each arm Dysphagia-optimized Intensity Modulated Radiotherapy (Do-IMRT) Standard (SIMRT) arm. Additional dose constraints applied the...
This study aimed to develop a functional model of subglottic stenosis by inducing direct airway irritation in transplanted mouse laryngotracheal complexes.Laryngotracheal complexes from C57BL/6 mice were harvested and divided into three groups: uninjured, mechanically injured chemically injured. Donor each group placed dorsal subcutaneous pockets recipient mice. Each week, the harvested, tissues fixed, sectioned, stained with haematoxylin eosin. Representative slides reviewed blinded...
A 34-year-old woman was referred from internal medicine with complaints of occasional upper abdominal heaviness and pain for 4 months. Her WHO performance score 1. On examination, she icteric had multiple, brownish nodular skin lesions on limbs back that were soft to firm in
Abstract Background: We undertook collagen injection laryngoplasty to achieve arytenoid augmentation in patients with dysphagia and persistent aspiration following partial laryngectomy, we evaluated the efficacy of aiding neoglottic closure ensuring airway safety. Methods: Two swallowing impairment after laryngectomy were studied. Swallowing was using fibre-optic endoscopy, modified barium swallow study. Collagen then injected into mucosa competence. Results: The followed up for two years....
Male breast cancer is rare and accounts for less than 1% of all cases worldwide.
<h3>Introduction</h3> Right iliac fossa pain (RIF) pain, caused by suspected acute appendicitis continues to prove diagnostically challenging with 15–30% of appendices removed being macroscopically normal. Diagnostic laparoscopy (DL) is used as both diagnostic and therapeutic procedure particularly in female patients. The aim this study was assess the rate negative appendicectomies (MNA) complications a cohort patients who had DL for appendicitis. Furthermore follow up re-admissions rates...