- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Practices and Patient Outcomes
- Palliative Care and End-of-Life Issues
- Cancer Treatment and Pharmacology
- Atrial Fibrillation Management and Outcomes
- Phase Equilibria and Thermodynamics
- Carbon Dioxide Capture Technologies
- Economic and Financial Impacts of Cancer
- Patient-Provider Communication in Healthcare
- Pharmaceutical Economics and Policy
- Medication Adherence and Compliance
- Catalysis and Oxidation Reactions
- Cancer survivorship and care
- Intensive Care Unit Cognitive Disorders
- Cardiac Arrest and Resuscitation
- Heart Failure Treatment and Management
- Healthcare Systems and Practices
- Venous Thromboembolism Diagnosis and Management
- Erythropoietin and Anemia Treatment
- Respiratory Support and Mechanisms
Leiden University Medical Center
2023-2025
Leiden University
2024
Delft University of Technology
1971
Background: Data on risks and benefits of long-term anticoagulants in patients with a life-limiting disease are limited. This cohort study aims to describe (dis)continuation incidences bleeding thromboembolic events vitamin K antagonist (VKA) users disease. Methods: from five Dutch anticoagulation clinics were linked data Statistics Netherlands the Cancer registry. Prevalent VKA diagnosed pre-specified between 01/01/2013 31/12/2019 included followed until 31/12/2019. Hospitalization used...
Even though antithrombotic therapy has probably little or even negative effects on the well-being of people with cancer during their last year life, deprescribing at end life is rare in practice. It often continued until death, possibly resulting excess bleeding, an increased disease burden and higher healthcare costs.The SERENITY consortium comprises researchers clinicians from eight European countries specialties different clinical fields, epidemiology psychology. will use a comprehensive...
Abstract The bubble‐point pressures in the NH 3 ‐CO 2 system, at complete chemical equilibrium, have been measured range of 130–185°c corresponding to 30–175 atm. system exhibits a sharp pressure minimum; area high concentration, critical behaviour and retrograde condensation found. results, as part ‐H O‐CO are discussed from standpoint phase theory shown be consistent with O CO systems. relation these measurements commercial urea synthesis is also discussed.
Background and ObjectivesFor patients receiving end-of-life care, adjusting polypharmacy deprescription of potentially harmful medicines are important impactors on quality-of-life. Antithrombotic therapies (ATT) used by 30-50% with cancer, rising to 80% in older cancer patients, often continued until a quality-of-life-impacting bleeding event, or patient is physically unable take oral medication. We aimed describe the use ATT occurrence clinical outcomes during care. ApproachLinked health...
IMPORTANCE: Mechanical power (MP) could serve as a valuable parameter in clinical practice to estimate the likelihood of adverse outcomes. However, safety thresholds for MP mechanical ventilation remain underexplored and contentious. OBJECTIVES: This study aims investigate association between hospital mortality across varying degrees lung disease severity, classified by Pa o 2 /F io ratios. DESIGN, SETTING, AND PARTICIPANTS: is retrospective cohort using automatically extracted data....