A5019985889- Palliative Care and End-of-Life Issues
- Grief, Bereavement, and Mental Health
- Patient-Provider Communication in Healthcare
- Venous Thromboembolism Diagnosis and Management
- Childhood Cancer Survivors' Quality of Life
- Geriatric Care and Nursing Homes
- Patient Dignity and Privacy
- Migration, Health and Trauma
- Ethics in Clinical Research
- Mental Health and Patient Involvement
- Delphi Technique in Research
- Family Support in Illness
- Cancer survivorship and care
- Advanced Radiotherapy Techniques
- Esophageal Cancer Research and Treatment
- Clinical practice guidelines implementation
- Lung Cancer Treatments and Mutations
- Health Systems, Economic Evaluations, Quality of Life
- Global Cancer Incidence and Screening
- Social Media in Health Education
- Intergenerational Family Dynamics and Caregiving
- Esophageal and GI Pathology
- Effects of Radiation Exposure
- Adolescent and Pediatric Healthcare
- Health Policy Implementation Science
Cardiff University
2016-2025
Marie Curie
2016-2025
Llanfrechfa Grange Hospital
2024
Ulster Hospital
2024
London North West Healthcare NHS Trust
2011-2024
Northwick Park Hospital
2024
Marie Curie Palliative Care Institute Liverpool
2012-2023
Department of Health and Social Care
2023
Queen's University Belfast
2012-2021
Marie Curie Hospice
2021
Thrombosis remains the most common preventable cause of mortality in cancer patients receiving chemotherapy. Whilst prophylaxis and treatment this condition is well understood, patient experience subsequent behavioral factors are not.Patients for cancer-associated thrombosis (CAT) were interviewed about their experiences CAT within context journey. Twenty interviews transcribed analyzed using framework analysis.Chemotherapy informed risks febrile neutropenia, how to recognize it, when seek...
Idiopathic pulmonary fibrosis (IPF) is a chronic, fibrotic interstitial lung disease of unknown origin. It has median survival three years but wide range in rate which difficult to predict at the time diagnosis. Specialist guidance promotes patient centred approach emphasising regular assessment, information giving and supportive care coordinated by multidisciplinary team (MDT). However understanding carer experience across trajectory limited detailed for MDTs on communication, triggers...
The prevalence of deep venous thrombosis in patients with advanced cancer is unconfirmed and it unknown whether current international thromboprophylaxis guidance applicable to this population. We aimed determine predictors femoral vein admitted specialist palliative care units (SPCUs).We did prospective longitudinal observational study five SPCUs England, Wales, Northern Ireland (four hospices one unit). Consecutive adults underwent bilateral ultrasonography on admission weekly until death...
The COVID-19 pandemic has been a devastating, mass bereavement event characterised by high levels of disruption to end-of-life, grieving and coping processes. Quantitative evidence is emerging on the effects grief outcomes, but rich qualitative lived experiences people bereaved during these times lacking.
Venous thromboembolism is a common complication of cancer and its treatments. Treatment cancer-associated thrombosis (CAT) differs from treatment in noncancer patients, requiring daily injection low-molecular-weight heparin (LMWH) for 6 months instead an oral anticoagulant. Previous research suggested LMWH acceptable intervention the CAT, yet clinical practice therapeutic opportunities have changed decade since study was conducted. Furthermore, previous there acknowledged selection bias...
Randomised trials are at the heart of evidence-based healthcare, but methods and infrastructure for conducting these sometimes complex studies largely evidence free. Trial Forge ( www.trialforge.org ) is an initiative that aims to increase base trial decision making and, in doing so, improve efficiency. This paper summarises a one-day workshop held Edinburgh on 10 July 2014 discuss how advance this initiative. We first outline problem inefficiency randomised go describe Forge. present...
Background: The COVID-19 pandemic is a mass bereavement event which has profoundly disrupted grief experiences. Understanding support needs and access to among people bereaved at this time crucial ensuring appropriate infrastructure. Aim: To investigate experiences, use of formal informal during the pandemic. Design: Baseline results from longitudinal survey. Support experiences accessing are reported using descriptive statistics thematic analysis free-text data. Setting/participants: 711...
To find out what inpatients with advanced cancer who are receiving palliative care think about the effect of thromoprophylaxis on overall quality life.Qualitative study using audiotaping semistructured interviews.Regional centre in Wales.28 metastatic and low molecular weight heparin.Recurring themes thromboprophylaxis life.Major emerging showed that patients knew risks venous thromboembolism purpose treatment heparin. Media coverage had raised awareness thromboembolism, many previous...
Family carers play an essential role in providing end-of-life care to their relatives but have been found experience uncertainty and a lack of confidence fulfilling caregiving roles, prompting recent calls for educational or information based resources be developed carers.We carried out four focus groups with Clinical Nurse Specialists, healthcare assistants, former current at hospice the UK, explore support needs family carers.Our findings previous research by highlighting number situations...
Research suggests that there may be bereavement experiences and support needs which are specific to family caregivers providing end of life care (EoLC), although this remains an under-researched area. This paper focuses on themes relating were derived from analysis free text survey responses collected in a research priority setting exercise for palliative EoLC. The involved public survey, designed generate priorities. Rather than identify topics, many people instead described their raised...
Symptom management is an essential aspect of palliative and end-of-life care, but evidence suggests that patients' symptoms may not always be relieved, causing significant harm to patients magnifying their relatives' distress. A growing body focuses on symptom at the end-of-life, research funding for care remains disproportionately low. It therefore crucial targeted areas importance relatives. The Palliative Priority Setting Partnership (PeolcPSP) undertook a UK-wide free-text survey...
To present and discuss the views of researchers at an academic palliative care research centre on encounters with terminally ill patients in home setting to generate a list recommendations for qualitative working end-of-life care.Eight took part consensus meeting their experiences undertaking interviews. The were varying backgrounds all reported having experience interviewing patients, but one had environment.The main areas discussed by included: whether participation unintentionally becomes...
Abstract Background Bereavement support is a core part of palliative care. However, the evidence base limited by lack consistency in outcomes used to evaluate services and models support, which makes it difficult compare approaches. Core Outcome Sets (COS) represent minimum that should be measured research into specific conditions or services. The aim this study was use stakeholders’ perspective develop COS for evaluating bereavement adults adult care settings. Methods A list relevant...
BackgroundPatients with advanced oesophageal cancer have a median survival of 3–6 months, and most require intervention for dysphagia. Self-expanding metal stent (SEMS) insertion is the typical form palliation in these patients, but dysphagia deterioration re-intervention are common. This study examined efficacy adjuvant external beam radiotherapy (EBRT) compared usual care alone preventing reducing service use after SEMS insertion.MethodsThis was multicentre, open-label, phase 3 randomised...
During the COVID-19 pandemic, many children and young people have experienced death of close family members, whilst also facing unprecedented disruption to their lives. This study aimed investigate experiences support needs bereaved from perspective parents guardians.We analysed cross-sectional qualitative free-text data a survey adults in UK during pandemic. Participants were recruited via media, social national associations community/charitable organisations. Thematic analysis was...
BackgroundA reduced exercise capacity is associated with increased morbidity and mortality in patients advanced non-small cell lung cancer (NSCLC). Therapeutic can be beneficial neuromuscular electrical stimulation (NMES) of the quadriceps muscles may represent a practical approach. The primary aim this study was to determine acceptability NMES NSCLC used alongside palliative chemotherapy. Secondary aims explored aspects safety efficacy setting. MethodsPatients due receive first-line...
Surgical trials have typically experienced recruitment difficulties when compared with other types of oncology trials. Qualitative studies an important role to play in exploring reasons for low recruitment, although date few such been carried out that are embedded surgical The BOLERO trial (Bladder cancer: Open versus Lapararoscopic or RObotic cystectomy) is a study determine the feasibility randomisation open laparoscopic access/robotic cystectomy patients bladder cancer. We describe...
Coping plays an essential role in maintaining the wellbeing of patients with cancer. A number different coping responses and strategies have been identified literature. The value relevance meaning based theory has also emphasised, including Antonovosky's Sense Coherence (SoC) theory. Ten advanced lung cancer were interviewed up to three times. total twenty depth interviews carried out, fully transcribed data analysed following a methodology Interpretative Phenomenological Analysis. Three...
Advance care planning is a key preparatory step in ensuring high-quality palliative and end of life care, should be considered as process, beginning with community-level conversations among lay persons. There is, however, indication that death talk community-dwelling adults not occurring, there dearth research examining why this the case. This study aims to provide first examination barriers facilitators talking about dying general population UK region (Northern Ireland), novel application...
Abstract Background The challenges and needs of people with brain tumours are complex unique, particularly - but not limited to the neurocognitive impacts they experience. These effects subsequently impactful on their primary caregivers. Evidence suggests glioma caregivers experience a range unmet in clinical care setting. Methods Semi-structured interviews across spectrum glioma, UK, as part study exploring core outcomes for use trials. Interviews were analysed using thematic analysis....
To undertake a mixed-methodology implementation study to improve the well-being of men with gastrointestinal late effects following radical radiotherapy for prostate cancer. All completed validated screening tool bowel (ALERT-B) and Gastrointestinal Symptom Rating Score (GSRS); positive score on ALERT-B were offered management peer reviewed algorithm pelvic radiation disease (PRD). Health-related quality life (HRQoL) at baseline, 6 12 months; healthcare resource usage (HRU) patient,...
Abstract Introduction This qualitative study explored patients’ experiences and perceptions of the SCOPE2 trial. The trial studied radiotherapy dose escalation in patients with inoperable oesophageal cancer treated definitive chemo-radiation. embedded a phase II for poor early response using positron emission tomography (PET) scans. Methods longitudinal interview took place between 2017 2021. Patients eligible chemoradiotherapy were recruited from five clinical sites UK. Participants invited...