A5101859222- Cancer-related gene regulation
- RNA Research and Splicing
- Renal and related cancers
- Chronic Myeloid Leukemia Treatments
- Erythrocyte Function and Pathophysiology
- Medicinal plant effects and applications
- Fungal Biology and Applications
- Mitochondrial Function and Pathology
- Chromatin Remodeling and Cancer
- Plant biochemistry and biosynthesis
- Neuroscience and Neuropharmacology Research
- Extracellular vesicles in disease
- Ion channel regulation and function
- MicroRNA in disease regulation
- Lung Cancer Treatments and Mutations
- Menopause: Health Impacts and Treatments
- Circular RNAs in diseases
- Genetic factors in colorectal cancer
- Wnt/β-catenin signaling in development and cancer
- Estrogen and related hormone effects
- Vestibular and auditory disorders
- Cancer Genomics and Diagnostics
- Cancer-related Molecular Pathways
- Nanoparticle-Based Drug Delivery
- Cancer-related molecular mechanisms research
Capital Medical University
2011-2024
Beijing Tongren Hospital
2021
Beijing Anzhen Hospital
2011-2021
Beijing Hospital of Traditional Chinese Medicine
2017
Circulating tumor DNA (ctDNA) has potential as a promising biomarker for molecular residual disease (MRD) detection in lung cancer. As the next‐generation sequencing standardized panel ctDNA emerges, its clinical utility needs to be validated. We prospectively recruited 184 resectable cancer patients from four medical centers. Serial postoperative ctDNAs were analyzed by panel. A total of 427 plasma samples 177 eligible enrolled. positivity after surgery was an independent predictor...
The transcription factor, Krüppel-like factor 4 (KLF4), plays an important role in regulating the proliferation of vascular smooth muscle cells. This study aimed to examine effect rapamycin on expression KLF4 and arterial neointimal formation.Expression was monitored using real-time PCR immunoblotting cultured rat carotid arteries vivo after balloon injury. Adenovirus-mediated overexpression siRNA-mediated knockdown were used mediating anti-proliferative . KLF4-regulated genes identified...
This study aims to summarize the clinical features and prognoses of malignant rhabdoid tumor kidney (MRTK) in children. It further analyze high-risk factors affecting MRTK prognosis.Clinical data from 14 children with treated Paediatrics Beijing Tongren Hospital January 2010 December 2019, along prognosis, were retrospectively analyzed.There included study, a median onset age 13 (3-46) months. Thirteen patients had distant metastases, most common site for metastases being inside lung. A...
The function of LINC00501, a long-non-coding RNA (lncRNA), is unclear at present. According to the Cancer Genome Atlas (TCGA), LINC00501 highly expressed in lung cancer (LC), but whether it can be adopted as potential therapy target for LC still needs further research.The expression was analyzed based on TCGA, and real-time fluorescent quantitative PCR assay carried out quantify non-small-cell (NSCLC). Additionally, bioinformatics analysis, luciferase reporter gene technique,...
New Findings What is the central question of this study? Does danthron alleviate experimental atherosclerosis by inhibiting formation foam cells? are main findings and their importance? Danthron improved serum lipid profiles significantly reduced atherosclerotic plaque areas accumulation in aortic root ApoE −/− mice. inhibited cell oxidized low‐density lipoprotein‐induced RAW264.7 macrophages. Furthermore, exerted its function at least partly through activating AMP‐activated protein...
Objective To study the characteristics of proton magnetic resonance spectroscopy (1H spectroscopy, 1H MRS) in patients with delayed encephalopathy following acute carbon monoxide poisoning (DEACOP) and its significance early diagnosis disease. Methods MRI MRS were performed 38 DEACOP 30 healthy volunteers. The ratios N-acetylaspartate ( NAA), Creatine Cr), Choline (Cho) peaks measured each volume interest, correlation Activity Daily Living Scale (ADL) Mini-Mental State Examination (MMSE)...
In recent years, with the domestic scholars understanding of BPPV levels increase and treatment effect high attention, Related research gradually, but most is to study curative manual reduction given priority to, for otolith fall off from bed separation root cause lack emphasis, relevant also relatively less. Therefore, previous studies, this paper mainly studied on pathogenesis literature review classified summarized. order further provide a scientific basis standardized treatment, thus...