A5101768004- Mycotoxins in Agriculture and Food
- Psoriasis: Treatment and Pathogenesis
- Dermatology and Skin Diseases
- Advanced biosensing and bioanalysis techniques
- Acupuncture Treatment Research Studies
- Biosensors and Analytical Detection
- Extracellular vesicles in disease
- Nanoplatforms for cancer theranostics
- Alzheimer's disease research and treatments
- Lipid metabolism and disorders
- Thyroid Disorders and Treatments
- Cancer-related molecular mechanisms research
- Environmental Quality and Pollution
- Neuroscience and Neuropharmacology Research
- RNA modifications and cancer
- Listeria monocytogenes in Food Safety
- Gut microbiota and health
- Plant Molecular Biology Research
- Advanced MRI Techniques and Applications
- Bacterial Infections and Vaccines
- MicroRNA in disease regulation
- RNA Research and Splicing
- Traditional Chinese Medicine Studies
- Tryptophan and brain disorders
- COVID-19 impact on air quality
China Agricultural University
2018-2025
Qingdao University
2025
Anhui University of Traditional Chinese Medicine
2025
China Pharmaceutical University
2025
Tianjin Medical University General Hospital
2022-2025
University of Waterloo
2024
Nanjing Foreign Language School
2023-2024
Capital Medical University
2021-2024
Xiangya Hospital Central South University
2024
Yunnan University
2024
Choline acetyltransferase (ChAT)-positive neurons in neural stem cell (NSC) niches can evoke adult neurogenesis (AN) and restore impaired brain function after injury, such as acute ischemic stroke (AIS). However, the relevant mechanism by which ChAT
Our previous study showed that Lactiplantibacillus plantarum Y42 in the biofilm state can produce more exopolysaccharides and surface-layer proteins a stronger promoting effect on intestinal barrier function than planktonic state. In this study, oral administration of live/pasteurized or L. its metabolites (exopolysaccharides proteins) increased expression Occludin, Claudin-1, ZO-1, MUC2 gut Balb/C mice after exposure to Listeria monocytogenes ATCC 19115 inhibited activation NLRP3...
ABSTRACT The heterogeneity of human umbilical cord mesenchymal stem cells (hUC‐MSCs) is culturing‐dependent, resulting in functional non‐uniformness. To achieve the best clinical benefit, a comprehensive understanding origin different culture systems can identify subgroups to direct precise application hUC‐MSCs. Here, we create single‐cell transcriptome atlas hUC‐MSC for identification subgroup Ultroser‐G‐MSCs with high osteogenic and chondrogenic potentials featured by expressions IL1R1...
ABSTRACT Background Glioma stem cells (GSCs) contribute to the initiation, recurrence, metastasis, and drug resistance of glioblastoma multiforme (GBM). Long noncoding RNAs (lncRNAs) are critical modulators in development progression GBM; however, specific lncRNAs related GSCs remain largely unexplored. This study aims identify dysregulated GSCs, unravel their contributions GBM progression, propose new targets for diagnosis treatment. Methods GeneChip analysis was utilized GSCs. The...
Background The interaction between illness perception, self-care ability, and health-promoting behaviors (HPB) in stable coronary artery disease (SCAD) patients remains uncertain. We conducted a cross-sectional survey to explore the correlation HPB among with SCAD, as well potential mediating role of perception ability HPB. Methods A study was carried out 184 inpatients SCAD Hefei, China, from December 2022 March 2023. Self-Care Coronary Heart Disease Inventory (SC-CHDI, containing three...
The neural basis of anxiety is unclear, which hinders the treatment disorders. Here, we found that αCaMKII+ neurons in medial prefrontal cortex (mPFCαCaMKII+) responded to stressors with increased activity both under physiological conditions and after repeated restraint stress (RRS) mice. Chemogenetic activation mPFCαCaMKII+ ameliorated stress-induced anxiety. A delayed increase expression growth hormone secretagogue receptor 1a (GHS-R1a), peripheral metabolic ghrelin, coincided reduced...
Antibiotic-resistant pathogens pose a significant global public health challenge, particularly in refractory infections associated with biofilms. The urgent development of innovative, safe, and therapeutically adaptive strategies to combat these resistant biofilms is essential. We present novel, precise, controllable photodynamic antibacterial carbon dot (B-M-CD) inspired by the natural properties mulberry leaf bacterial targeting function boric acid. This photocatalytic agent exhibits good...
A time-resolved fluorescent immunochromatographic assay (TRFICA) was successfully developed for the sensitive, simultaneous, and quantitative detection of aflatoxin B1 (AFB1) zearalenone (ZEN) in Chinese herbal medicines. Eu-nanospheres (EuNPs) with unique optical properties increased stability sensitivity assay. To obtain stable results, we applied a three-label system which monoclonal antibodies AFB1 ZEN were conjugated to EuNPs as probes on test line (T line), EuNP-labelled chicken IgY...
Cataract is one of the major causes blindness in world. Its early detection and treatment could greatly reduce risk deterioration blindness. Instruments commonly used to detect cataracts are slit lamps fundus cameras, which highly expensive require domain knowledge. Thus, problem that lack professional ophthalmologists result delay cataract detection, where medical inevitable. Therefore, this study aimed design a convolutional neural network (CNN) with digital camera images (CNNDCI) system...
Adaptation to hypoxia has attracted much public interest because of its clinical significance. However, hypoxic adaptation in the body is complicated and difficult fully explore. To explore previously unknown conserved mechanisms key proteins involved different species, we first used a yeast model for mechanistic screening. Further multi-omics analyses multiple species including yeast, zebrafish mice revealed that glycerophospholipid metabolism was significantly with up-regulation...
Bile acids (BAs) exert a profound influence on the body's pathophysiology by intricately shaping composition of gut bacteria. However, complex interplay between BAs and microbiota has impeded systematic exploration their impact intestinal Initially, we investigated effects 21 growth 65 bacterial strains in vitro. Subsequently, examined overall bacteria, both vivo The results unveiled distinct various different diverse impacts Mechanistically, inhibition occurs through accumulation these...