A5041752671- Intracerebral and Subarachnoid Hemorrhage Research
- Glioma Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Advanced MRI Techniques and Applications
- MicroRNA in disease regulation
- Traumatic Brain Injury and Neurovascular Disturbances
- Advanced Neuroimaging Techniques and Applications
- Cancer Mechanisms and Therapy
- Epilepsy research and treatment
- Intracranial Aneurysms: Treatment and Complications
- Shoulder Injury and Treatment
- Extracellular vesicles in disease
- Cancer-related molecular mechanisms research
- Foot and Ankle Surgery
- Circular RNAs in diseases
- Exercise and Physiological Responses
- Plant Molecular Biology Research
- Tendon Structure and Treatment
- Tea Polyphenols and Effects
- Vascular Malformations Diagnosis and Treatment
- UAV Applications and Optimization
- Functional Brain Connectivity Studies
- Diabetic Foot Ulcer Assessment and Management
- EEG and Brain-Computer Interfaces
- Distributed Control Multi-Agent Systems
Tianjin Medical University General Hospital
2016-2025
Shanghai Jiao Tong University
2022-2025
Shanghai Ninth People's Hospital
2022-2025
Ministry of Education of the People's Republic of China
2013-2025
Yantai Academy of Agricultural Sciences
2023-2024
Hunan Agricultural University
2022-2023
Xinjiang University
2023
Tianjin Medical University
2008-2022
Shijiazhuang University
2021
Xi'an Jiaotong University
2021
Plant tandem CCCH zinc finger (TZF) proteins play diverse roles in developmental and adaptive processes. Arabidopsis C3H14 has been shown to act as a potential regulator of secondary wall biosynthesis. However, there is lack direct evidence support its functions Arabidopsis. It demonstrated here that homologue C3H15 redundantly regulate formation they additionally function anther development. Plants with double, but not single, T-DNA mutants for or have few pollen grains thinner stem walls...
Summary Wood biomass is mainly made of secondary cell walls, whose formation controlled by a multilevel network. The tandem CCCH zinc finger ( TZF ) proteins involved in plant wall are poorly understood. Two genes, P d C 3 H 17 and 18 , were isolated from opulus deltoides functionally characterized E scherichia coli tobacco, A rabidopsis poplar. predominantly expressed cells developing wood, the they encode targeted to cytoplasmic foci. Transcriptional activation assays showed that MYB...
In plants, the R2R3-MYB gene family contains many pairs of paralogous genes, which play diverse roles in developmental processes and environmental responses. The paper reports characterization 81 Populus genes. Chromosome placement, phylogenetic, motif structure analyses showed that these resulted from multiple types duplications had five different fates. Tissue expression patterns revealed most duplicated genes were specifically expressed tissues examined. qRT-PCR confirmed nine highly...
The authors sought to test the hypothesis that adding dexamethasone (DXM) atorvastatin (ATO) potentiates effects of ATO on chronic subdural hematoma (CSDH).
In this study, screening bacteriocin-producing strains from 2,000 plant-derived by agar well diffusion method was conducted. The corresponding produced bacteriocin purified and identified Sephadex gel chromatography, reversed-phase high-performance liquid chromatography (RP-HPLC), coupled with tandem mass spectrometry (LC-MS/MS). Meanwhile, the biological characteristics of were investigated. targeted strain W3-2 obtained as Lactobacillus plantarum morphological observation 16S rRNA gene...
Past research suggests that many individuals take Massive Open Online Courses (MOOCs) for employment-related reasons. It is unclear, however, how learners leverage MOOCs employment and effectively these platforms support employability. To explore this further, we surveyed 441 interviewed 22 motivated to reasons related financial limitations and/or employment. Using the three dimensions of employability as a framework-human social capital, career identity, personal adaptability-we find while...
Background: Post-traumatic joint contracture (PTJC) mainly manifests as excessive inflammation leading to capsule fibrosis. Transforming growth factor (TGF)-β1, a key regulator of and fibrosis, can promote fibroblast activation, proliferation, migration, differentiation into myofibroblasts. Platelet-rich plasma (PRP) is considered have strong potential for improving tissue healing regeneration, the ability treat fibrosis remains largely unknown. Methods: In this study, we aimed determine...
Cellular bioactivity and tissue regeneration can be affected by coatings on tissue-engineered scaffolds. Using mussel-inspired polydopamine (PDA) is a convenient effective approach to surface modification. Therefore, 3D-printed β-tricalcium phosphate (β-TCP) scaffolds were coated with PDA in this study. The effects of the adhesion osteogenic differentiation seeded bone marrow mesenchymal stem cells (BMSCs) vitro new-bone formation vivo investigated. potential mechanisms related differential...
Abstract Background The discovery of the glymphatic system and meningeal lymphatic vessels challenged traditional view regarding lack a in central nervous system. It is now known that intracranial plays an important role fluid transport, macromolecule uptake, immune cell trafficking. Studies have also shown function significantly associated with neurological diseases; for example, impaired can lead to Tau deposition increased lymphocyte count brain tissue mice subarachnoid hemorrhage....
Abstract Previous observational investigations suggest that structural and diffusion imaging-derived phenotypes (IDPs) are associated with major neurodegenerative diseases; however, whether these associations causal remains largely uncertain. Herein we conducted bidirectional two-sample Mendelian randomization analyses to infer the relationships between IDPs diseases using common genetic variants-single nucleotide polymorphism (SNPs) as instrumental variables. Summary statistics of...
ABSTRACT Background Glioma stem cells (GSCs) contribute to the initiation, recurrence, metastasis, and drug resistance of glioblastoma multiforme (GBM). Long noncoding RNAs (lncRNAs) are critical modulators in development progression GBM; however, specific lncRNAs related GSCs remain largely unexplored. This study aims identify dysregulated GSCs, unravel their contributions GBM progression, propose new targets for diagnosis treatment. Methods GeneChip analysis was utilized GSCs. The...
Muscle atrophy is a pathological condition characterized by the excessive degradation of muscle proteins, leading to impaired physical performance. Isoliquiritigenin (ISL) promising extract known for its medical effects; however, impact on remains unclear. We investigated effects ISL both in vitro and vivo. The results showed that 5-µM exhibited no significant cytotoxicity C2C12 cells, as reflected cell count kit-8 5-ethynyl-2'-deoxyuridine (EdU) tests. increased diameter myotubes...
Background and objectives Patients suffering from severe spontaneous intracerebral hemorrhage (SSICH) are at high risk of cardiocerebrovascular diseases postoperatively, which hugely affect patients’ long-term outcomes. Metabolic features could reflect the pathological change system might serve as biomarkers for evaluating poor outcomes in SSICH patients. The current study aimed to find early-warning patients after surgery. Methods Severe receiving surgical treatment a referring hospital...
Chronic subdural hematoma (CSDH) is a neurological disorder with substantial recurrence rate. Atorvastatin an effective drug for treating hyperlipidemia and known to improve outcome after intracerebral hemorrhage. Previous studies have reported that atorvastatin treatment promotes absorption in CSDH, while the underlying mechanisms remain unclear. In this study, we investigated whether anti-inflammatory effects of mediate CSDH. 144 male, Wistar rats (6 months old) were randomly divided into...
// Jikui Sun 1, * , Zhifan Jia 2, Banban Li 3, Anling Zhang 2 Guangxiu Wang Peiyu Pu Zhijuan Chen Zengguang and Weidong Yang 1 Department of Neurosurgery, Affiliated Hospital Taishan Medical University, Life Science Research Center Taian, 271000, P.R. China Tianjin University General Hospital, Neurological Institute, Key Laboratory Post-trauma Neuro-repair Regeneration in Central Nervous System, Ministry Education, Injuries, Variations Tianjin, 300052, 3 Hematopathology, These authors...
The unmanned aerial vehicles (UAVs) networks are very vulnerable to smart jammers that can choose their jamming strategy based on the ongoing channel state accordingly. Although reinforcement learning (RL) algorithms give UAV ability make intelligent decisions, high-dimensional space makes it difficult for converge quickly. This article proposes a knowledge-based RL method, which uses domain knowledge compress agent needs explore and then improve algorithm convergence speed. Specifically, we...
Bone defect is a serious orthopedic disease which has been studied for long time. Alternative degradable biomaterials are required bone repairing and regeneration to address the limitation of autogenous bone. β-tricalcium phosphate (β-TCP) an alternative material with good cytocompatibility used in treatment. However, whether β-TCP contributes osteogenesis marrow stem cells (BMSCs) through N6-methyladenosine (m6A) modification remains unknown. To this issue, we verified effects on BMSCs. We...