A5013555043- Functional Brain Connectivity Studies
- Viral Infections and Vectors
- Genetic Associations and Epidemiology
- Advanced Neuroimaging Techniques and Applications
- Vector-borne infectious diseases
- Mosquito-borne diseases and control
- Neural dynamics and brain function
- Mental Health Research Topics
- Respiratory viral infections research
- Genetics and Neurodevelopmental Disorders
- COVID-19 epidemiological studies
- Migraine and Headache Studies
- Autism Spectrum Disorder Research
- SARS-CoV-2 and COVID-19 Research
- Advanced MRI Techniques and Applications
- Cognitive Abilities and Testing
- Forest Insect Ecology and Management
- Climate Change and Health Impacts
- Viral gastroenteritis research and epidemiology
- Bioinformatics and Genomic Networks
- Zoonotic diseases and public health
- Yersinia bacterium, plague, ectoparasites research
- Viral Infections and Outbreaks Research
- Animal Disease Management and Epidemiology
- Epigenetics and DNA Methylation
Tianjin Medical University General Hospital
2015-2025
Ningbo University
2024-2025
Zunyi Medical University
2025
Academy of Military Medical Sciences
2024
Institute of Microbiology
2021-2024
Second Affiliated Hospital of Zhejiang University
2023
Tianjin Medical University
2021
Beijing Forestry University
2019-2021
First Affiliated Hospital of Nanchang University
2019
Nanchang University
2019
Nationwide nonpharmaceutical interventions (NPIs) have been effective at mitigating the spread of novel coronavirus disease (COVID-19), but their broad impact on other diseases remains under-investigated. Here we report an ecological analysis comparing incidence 31 major notifiable infectious in China 2020 to average level during 2014-2019, controlling for temporal phases defined by NPI intensity levels. Respiratory and gastrointestinal or enteroviral declined more than sexually transmitted...
To combat the coronavirus disease 2019 (COVID-19) pandemic, nonpharmaceutical interventions (NPIs) were implemented worldwide, which impacted a broad spectrum of acute respiratory infections (ARIs).Etiologically diagnostic data from 142 559 cases with ARIs, who tested for 8 viral pathogens (influenza virus [IFV], syncytial [RSV], human parainfluenza [HPIV], adenovirus [HAdV], metapneumovirus [HMPV], [HCoV], bocavirus [HBoV], and rhinovirus [HRV]) between 2012 2021, analyzed to assess changes...
Although both schizophrenia and gray matter volume (GMV) show high heritability, however, genes accounting for GMV alterations in remain largely unknown. Based on risk identified by the genome-wide association study of Schizophrenia Working Group Psychiatric Genomics Consortium, we used transcription-neuroimaging analysis to test that which these are associated with changes schizophrenia. For each brain tissue sample, expression profiles 196 were extracted from six donated normal brains...
Non pharmaceutical interventions (NPI) including hand washing directives were implemented in China and worldwide to combat the COVID-19 pandemic, which are likely have had impacted a broad spectrum of enteric pathogen infections.Etiologically diagnostic data from 45 937 67 395 patients with acute diarrhea between 2012 2020, who tested for seven viral pathogens 13 bacteria respectively, analyzed assess changes infections during first pandemic year compared pre-pandemic years.Test positive...
Resting-state functional connectivity in the human brain is heritable, and previous studies have investigated genetic basis underlying connectivity. However, at present, molecular mechanisms associated with network centrality are still largely unknown. In this study, networks were constructed, graph-theory method was employed to calculate 100 healthy young adults from Human Connectome Project. Specifically, strength (FCS), also known as "degree centrality" of weighted networks, calculated...
Air pollution is a major risk factor for planetary health and has long been suspected of predisposing humans to respiratory diseases induced by pathogens like influenza viruses. However, epidemiological evidence remains elusive due lack longitudinal data from large cohorts.
Sirex nitobei, an Asian native wood wasp species, is a major pest in coniferous commercial forestry, infesting and weakening conifers through its obligate mutualism with wood-rotting fungus species. The combination of larvae mutualistic causes the breakdown plant vascular tissue, leading to eventually death, as well high economic cost forestry. Since it was first recorded China early 1980s, S. nitobei has widely spread become successfully established. Despite extensive distribution range,...
The geographic expansion of mosquitos is associated with a rising frequency outbreaks mosquito-borne diseases (MBD) worldwide. We collected occurrence locations and times mosquito species, arboviruses, MBDs in the mainland China 1954−2020. mapped spatial distributions mosquitoes arboviruses at county level, we used machine learning algorithms to assess contributions ecoclimatic, socioenvironmental, biological factors 26 predominant species two high disease burden. Altogether, 339 35 were...
Abstract The rodents and shrews are important reservoirs for a large number of zoonotic pathogens. Here by performing literature review, we determined the occurrence distribution in China at three scales including province, city, county levels. peer-reviewed papers published English Chinese were collected, standard procedures applied reference books, field surveys websites to remove duplicates, information on recorded locations was extracted. dataset contains 13,911 records geo-referenced...
Lyme borreliosis, recognized as one of the most important tick-borne diseases worldwide, has been increasing in incidence and spatial extent. Currently, there are few geographic studies about distribution borreliosis risk across China. Here we established a nationwide database that involved Borrelia burgdorferi sensu lato (B. burgdorferi) detected humans, vectors, animals The eco-environmental factors shaped pattern B. were identified by using two-stage boosted regression tree model...
Depressive disorder prevalence in patients with schizophrenia has been reported to be 40%. People low socioeconomic status (SES) are more likely suffer from and major depressive (MDD). However, the causal relationship between depression potential mediating role of SES remains unclear. Two-sample Mendelian randomization (MR) analyses were conducted explore bidirectional MDD largest sample size European ancestry public genome-wide association studies (sample ranged 130,644 480,359). Inverse...
Abstract Previous research has suggested a correlation between socioeconomic status (SES) and mental diseases, while personality traits may be associated with SES the risk of disorders. However, causal nature these associations remains largely uncertain. Our Mendelian randomization (MR) study aims to explore bidirectional causality disorders, as well evaluate potential mediating role in associations. Using MR approach, we assessed indicators We then used two-step method further investigate...
Abstract Previous observational investigations suggest that structural and diffusion imaging-derived phenotypes (IDPs) are associated with major neurodegenerative diseases; however, whether these associations causal remains largely uncertain. Herein we conducted bidirectional two-sample Mendelian randomization analyses to infer the relationships between IDPs diseases using common genetic variants-single nucleotide polymorphism (SNPs) as instrumental variables. Summary statistics of...
We have studied the effect of random long-range connections in chaotic thermosensitive neuron networks with each being capable exhibiting diverse bursting behaviors, and found stochastic synchronization optimal spatiotemporal patterns. For a given coupling strength, burst-firings neurons become more synchronized as number (or randomness) is increased and, rather, most pronounced pattern appears for an randomness. As strength increased, randomness shifts towards smaller strength. This result...
Schizophrenia is a mental health disorder characterized by functional dysconnectivity. Eigenvector centrality mapping (ECM) has been employed to investigate alterations in connectivity schizophrenia, yet the results lack consistency, and genetic mechanisms underlying these changes remain unclear. In this study, whole-brain voxel-wise ECM analyses were conducted on resting-state magnetic resonance imaging data. A cohort of 91 patients with schizophrenia matched healthy controls included...
Viral pathogens belonging to the order Bunyavirales pose a continuous background threat global health, but fact remains that they are usually neglected and their distribution is still ambiguously known. We aim map geographical of viruses assess environmental suitability transmission risk major in China.