A5046689924- Bacteriophages and microbial interactions
- Antimicrobial Resistance in Staphylococcus
- Microbial infections and disease research
- Genomics and Phylogenetic Studies
- Bacterial biofilms and quorum sensing
- Monoclonal and Polyclonal Antibodies Research
- Antimicrobial Peptides and Activities
- Bacterial Genetics and Biotechnology
- Microbial Metabolism and Applications
- Bacterial Identification and Susceptibility Testing
- Virology and Viral Diseases
- Biochemical and Structural Characterization
- Probiotics and Fermented Foods
- Advanced biosensing and bioanalysis techniques
- Bacillus and Francisella bacterial research
- RNA and protein synthesis mechanisms
- Pharmaceutical and Antibiotic Environmental Impacts
- Virus-based gene therapy research
Masaryk University
2012-2019
Staphylococcus aureus is a serious human and veterinary pathogen in which new strains with increasing virulence antimicrobial resistance occur due to acquiring genes by horizontal transfer. It generally accepted that temperate bacteriophages play major role gene In this study, we proved the presence of various bacterial S. COL strain directly within phage particles via qPCR quantified their packaging frequency. Non-parametric statistical analysis showed transducing φ11, φ80 φ80α serogroup B,...
Abstract Lytic bacteriophages are valuable therapeutic agents against bacterial infections. There is continual effort to obtain new phages increase the effectivity of phage preparations emerging phage-resistant strains. Here we described genomic diversity spontaneous host-range mutants kayvirus 812. Five mutant were isolated as rare plaques on Staphylococcus aureus The host range 812-derived was 42% higher than wild type, determined a set 186 methicillin-resistant S. strains representing...
In Staphylococcus aureus, generalized transduction mediated by temperate bacteriophages represents a highly efficient way of transferring antibiotic resistance genes between strains. the present study, we identified and characterized in detail new efficiently transducing bacteriophage family Siphoviridae, designated ϕJB, which resides as prophage meticillin-resistant S. aureus (MRSA) strain Jevons B. Whole-genome sequencing followed detailed silico analysis uncovered linear dsDNA genome...