A5020799390- Advanced biosensing and bioanalysis techniques
- Reproductive Biology and Fertility
- Epigenetics and DNA Methylation
- Assisted Reproductive Technology and Twin Pregnancy
- Carbon and Quantum Dots Applications
- Nanocluster Synthesis and Applications
- DNA and Nucleic Acid Chemistry
- RNA Interference and Gene Delivery
- Reproductive Health and Technologies
- Advancements in Battery Materials
- Sperm and Testicular Function
- Electrocatalysts for Energy Conversion
- Birth, Development, and Health
- Graphene and Nanomaterials Applications
- DNA Repair Mechanisms
- Pregnancy and preeclampsia studies
- Advanced Nanomaterials in Catalysis
- Gold and Silver Nanoparticles Synthesis and Applications
- Genetic Syndromes and Imprinting
- Electromagnetic Fields and Biological Effects
- Prenatal Screening and Diagnostics
- Plant tissue culture and regeneration
- Biosensors and Analytical Detection
- Hydrogels: synthesis, properties, applications
- Animal Genetics and Reproduction
Zhengzhou University
2024
Air Force Medical University
2013-2022
Northwest A&F University
2008-2022
Ningbo University of Technology
2022
Zhejiang Sci-Tech University
2021-2022
Ministry of Agriculture, Livestock, and Food Supply
2022
Qilu University of Technology
2020-2021
Molina Center for Energy and the Environment
2020
Tang Du Hospital
2019
Guangxi Normal University
2015-2017
NiFe alloy NPs anchored in NGHS wrapped with self-grown NCNTs a three-dimensional architecture was constructed successfully for ORR/OER bifunctional catalysis.
DNA methylation disturbance is associated with defective human sperm. However, oligozoospermia (OZ) and asthenozoospermia (AZ) usually present together, the relationship between single-phenotype defects in sperm poorly understood. In this study, 20 infertile OZ patients AZ were compared fertile normozoospermic men. Bisulfate-specific PCR was used to analyze of H19-DMR DAZL promoter these subjects. A similar pattern detected NZ(control), only complete mild hypomethylation(<50% unmethylated...
Serum starvation is a routine protocol for synchronizing nuclear donor cells to G0/G1 phase during somatic cell transfer (SCNT). However, abrupt serum deprivation can cause serious stress the cultured in vitro, which might result endoplasmic reticulum (ER) stress, chromosome damage, and finally reduce success rate of SCNT. In present study, effects tauroursodeoxycholic acid (TUDCA), an effective ER stress-relieving drug, on under condition as well following SCNT procedures were first...
Sperm morphology is the best predictor of fertilization potential, and critical predictive information for supporting assisted reproductive methods selection. Given its important value declining reality semen quality in recent years, threshold normal sperm rate (NSMR) being constantly corrected controversial, from 4th edition (14%) to 5th version (4%). We retrospectively analyzed 4756 cases infertility patients treated with conventional-IVF(c-IVF) or ICSI, which were divided into three...
Abstract Vitrification is increasingly used in assisted reproductive technology (ART) laboratories worldwide, and potential vitrification‐induced risks require further exploration. The effect of vitrification on changes DNA methylation imprinting disorders was investigated E9.5 mouse fetuses placentas. Fetus placental tissues were collected from the natural mating (nautural conception [NC]) group, vitro culture (IVC) group vitrified embryo transfer (VET) group. fetal crown‐rump length at...
Abstract Drug delivery systems refer to a technical system capable of comprehensively regulating the distribution drugs in living body terms time, space and dose. As thermosensitive smart materials, Poly(N-isopropylacrylamide) (PNIPAM) is an ideal treatment platform for development drug systems. This article focuses on application various thermally sensitive materials such as nanoparticles, nanofibers, hydrogels, self-assembled micelles prepared by PNIPAM recent years. The future also discussed.
A sensitive fluorescence detection method for DNA methyltransferase is developed based on graphene oxide and T7 exonuclease-assisted signal amplification.
A label-free and sensitive assay for apurinic/apyrimidinic endonuclease 1 was achieved based on isothermal amplification G-quadruplex/ligand recognition.
A label free fluorescent assay for uracil-DNA glycosylase activity was developed based on the signal amplification of exonuclease I.
Environmental influences during early development increase the susceptibility to metabolism diseases in adulthood. Assisted reproductive techniques (ART) expose gametes or preimplantation embryo a nonphysiological environment that increases risk of later life. However, precise underlying causes ART-related disease remain unclear. In our previous study, by using mouse model, we found ART resulted placental maldevelopment and dysfunction led reduced fetal growth. The lipid transporters...
In vitro fertilization (IVF) has wide application in human infertility and animal breeding. It is also used for research on reproduction, fertility development. However, IVF embryos are still inferior to their vivo counterparts. Some substances seminal plasma appear have important roles embryo development, during the traditional procedure, washed away. this study, extracellular vesicles (EVs) were concentrated from by ultracentrifugation, visualized using transmission electron microscopy,...
A surface-enhanced Raman scattering (SERS) system for the simple, sensitive and homogeneous detection of UDG activity based on silver nanorods (AgNRs) was developed.
Nowadays, concerns about the harmful effects of radiofrequency electromagnetic radiation (RF-EMR) on male fertility and offspring health are growing. In present study, we investigated long-term exposure (at least 10 weeks) to RF-EMR [2.0 GHz; power density, 2.5 W/m 2 ; whole-body specific absorption rate (SAR), 0.125–0.5 W/kg] mice F1 growth glucose metabolism. No significant injuries were observed in testis organization, sperm quality, pregnancy rate. However, exposed exhibited a...
Cu2+ can catalyze the chemical reaction between hydrogen peroxide (H2O2) and 2,2'-Azinobis-(3-ethylbenzthiazoline-6-sulphonate) (ABTS) effectively bring change of absorbance. Glucose oxidase (GOD) glucose oxidation to produce H2O2. The content be determined indirectly by measuring pH value, H2O2 concentration, temperature time were investigated optimized in experiment. Under optimal conditions, a linear relationship concentration root absorbance could obtained over range 100 μM ~ 10 mM. is A...
This study aimed to investigate the effects of 3-hydroxyflavone, a natural antioxidant pigment enriched in vegetables, on developmental cellular and molecular characteristics bovine somatic-cell nuclear transfer (SCNT) embryos. There were no significant differences cleavage rate at 48 hr culture or inner cell mass (ICM)-to-trophectoderm (TE) ratio between 3-hydroxyflavone addition untreated (control) groups (P > 0.05). (20 µM) did, however, increase 24 blastocyst-formation Days 6 7 < 0.05);...
The research situation of the application carbon quantum dot fluorescent materials to detection metal ions, including current status and preface recent years, development trends are summarized. ions is highlighted, iron copper mercury lead silver ions. Finally, problems prospects for detecting discussed.
Liquid-metal nanoparticles (LM NPs) are highly promising for diverse applications, including thermal management, flexible electronics, etc. However, controlled preparation of colloidal LM NPs with a narrow size distribution and small diameter via conventional methods was still challenging. Herein, we reported robust route to fabricate uniform gallium/indium (EGaIn) utilizing starlike poly(4-vinylpyridine)-b-polystyrene (P4VP-b-PS) copolymers as nanoreactors. Ultrafine EGaIn nanodroplets...