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Research Areas
- Cancer, Hypoxia, and Metabolism
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
Universidad UTE
2020
ABSTRACT Many primary-tumor subregions have low levels of molecular oxygen, termed hypoxia. Hypoxic tumors are at elevated risk for local failure and distant metastasis. Metastatic disease is the leading cause cancer-related deaths involves critical interactions between tumor cells microenvironment. Here we focused on elucidating hallmarks hypoxia that remains poorly defined. To fill this gap, analyzed genomic alterations score 233 hypoxia-related genes 6,343 individuals across 17 TCGA...
10.1101/2020.02.01.930479
preprint
EN
bioRxiv (Cold Spring Harbor Laboratory)
2020-02-02
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