Maria S. Barrios

ORCID: 0000-0001-9695-8608
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About
Contact & Profiles
Research Areas
  • Electrolyte and hormonal disorders
  • Immune Response and Inflammation
  • Renal function and acid-base balance
  • Gut microbiota and health
  • Clostridium difficile and Clostridium perfringens research
  • Probiotics and Fermented Foods
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Mycobacterium research and diagnosis
  • Epilepsy research and treatment
  • Intensive Care Unit Cognitive Disorders

Mayo Clinic in Florida
2022-2024

Jacksonville College
2022-2023

Indiana University – Purdue University Indianapolis
2021

Signal transducer and activator of transcription 4 (STAT4) is expressed in hematopoietic cells plays a key role the differentiation T helper 1 cells. Although STAT4 required for immunity to intracellular pathogens, cell-independent protective mechanisms are not clearly defined. In this report, we demonstrate that STAT4-deficient mice were acutely sensitive methicillin-resistant Staphylococcus aureus (MRSA) infection. We show was neutrophils activated by IL-12 via JAK2-dependent pathway....

10.1172/jci.insight.141326 article EN cc-by JCI Insight 2021-06-17

A man in his 60s presented to the emergency room with fever and fatigue after a 2.5-month course of corticosteroids. His medical history was significant for bioprosthetic aortic valve replacement moderately severe ulcerative colitis treated balsalazide daily lactobacillus-containing probiotics. Initial investigations revealed Lactobacillus rhamnosus bacteraemia without complication. Four days hospital discharge, patient experienced acute-onset right-sided paraesthesia lower-limb paresis. On...

10.1136/bcr-2022-249020 article EN BMJ Case Reports 2022-06-01

Hyponatraemia on hospital admission is associated with increased length of stay, healthcare expenditures and mortality. Urine studies collected before fluid or diuretic administration are essential to diagnose the underlying cause hyponatraemia, thereby empowering admitting teams employ appropriate treatment. A multidisciplinary quality improvement (QI) team led by internal medicine residents performed a QI project from July 2020 through June 2021 increase rate urine in emergency department...

10.1136/bmjoq-2023-002326 article EN cc-by-nc BMJ Open Quality 2023-09-01
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