- Electrolyte and hormonal disorders
- Immune Response and Inflammation
- Renal function and acid-base balance
- Gut microbiota and health
- Clostridium difficile and Clostridium perfringens research
- Probiotics and Fermented Foods
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Mycobacterium research and diagnosis
- Epilepsy research and treatment
- Intensive Care Unit Cognitive Disorders
Mayo Clinic in Florida
2022-2024
Jacksonville College
2022-2023
Indiana University – Purdue University Indianapolis
2021
Signal transducer and activator of transcription 4 (STAT4) is expressed in hematopoietic cells plays a key role the differentiation T helper 1 cells. Although STAT4 required for immunity to intracellular pathogens, cell-independent protective mechanisms are not clearly defined. In this report, we demonstrate that STAT4-deficient mice were acutely sensitive methicillin-resistant Staphylococcus aureus (MRSA) infection. We show was neutrophils activated by IL-12 via JAK2-dependent pathway....
A man in his 60s presented to the emergency room with fever and fatigue after a 2.5-month course of corticosteroids. His medical history was significant for bioprosthetic aortic valve replacement moderately severe ulcerative colitis treated balsalazide daily lactobacillus-containing probiotics. Initial investigations revealed Lactobacillus rhamnosus bacteraemia without complication. Four days hospital discharge, patient experienced acute-onset right-sided paraesthesia lower-limb paresis. On...
Hyponatraemia on hospital admission is associated with increased length of stay, healthcare expenditures and mortality. Urine studies collected before fluid or diuretic administration are essential to diagnose the underlying cause hyponatraemia, thereby empowering admitting teams employ appropriate treatment. A multidisciplinary quality improvement (QI) team led by internal medicine residents performed a QI project from July 2020 through June 2021 increase rate urine in emergency department...