Christos D. Georgiou

ORCID: 0000-0001-9707-0109
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About
Contact & Profiles
Research Areas
  • Plant pathogens and resistance mechanisms
  • Sulfur Compounds in Biology
  • Photosynthetic Processes and Mechanisms
  • Genomics, phytochemicals, and oxidative stress
  • Biochemical effects in animals
  • Antioxidant Activity and Oxidative Stress
  • Redox biology and oxidative stress
  • Plant responses to elevated CO2
  • Environmental Toxicology and Ecotoxicology
  • Planetary Science and Exploration
  • Astro and Planetary Science
  • Photoreceptor and optogenetics research
  • Maternal and fetal healthcare
  • Hemoglobin structure and function
  • Mitochondrial Function and Pathology
  • Advanced Glycation End Products research
  • Trace Elements in Health
  • Fungal Biology and Applications
  • Origins and Evolution of Life
  • Plant Pathogens and Fungal Diseases
  • Mycotoxins in Agriculture and Food
  • Free Radicals and Antioxidants
  • bioluminescence and chemiluminescence research
  • Vitamin C and Antioxidants Research
  • Maternal and Perinatal Health Interventions

University of Patras
2015-2024

University of Thessaly
2021-2024

The Royal Melbourne Hospital
2024

National and Kapodistrian University of Athens
2023

Leeds Teaching Hospitals NHS Trust
2021

Leeds General Infirmary
2021

University of Cyprus
2019-2020

Technological Educational Institute of Central Greece
2009-2019

All-Russian Scientific Research Institute of Experimental Veterinary Sciences. Ya.R. Kovalenko
2019

Russian Academy of Sciences
2019

Previous studies showed that the coronavirus disease 2019 (COVID-19) lockdown imposed changes in adults’ lifestyle behaviors; however, there is limited information regarding effects on youth. The COV-EAT study aimed to report children’s and adolescents’ habits during first COVID-19 explore potential associations between of participants’ behaviors body weight. An online survey among 397 children/adolescents their parents across 63 municipalities Greece was conducted April–May 2020. Parents...

10.3390/nu13030930 article EN Nutrients 2021-03-13

Sclerotium-forming filamentous fungi are of great agricultural and biological interest because they can be viewed as models simple metamorphosis. They differentiate by asexually producing sclerotia but the processes involved in sclerotial metamorphosis were poorly understood. In 1997, it was shown for first time that differentiation state Sclerotium rolfsii concurred with increasing levels lipid peroxides. This finding prompted development a theory supporting is induced oxidative stress....

10.1093/icb/icj034 article EN Integrative and Comparative Biology 2006-04-27

The combination of intense solar radiation and soil desiccation creates a short circuit in the biogeochemical carbon cycle, where soils release significant amounts CO2 reactive nitrogen oxides by abiotic oxidation. Here we show that desert accumulate metal superoxides peroxides at higher levels than non-desert soils. We also photogeneration equimolar superoxide hydroxyl radical desiccated aqueous soils, respectively, photo-induced electron transfer mechanism supported their mineralogical...

10.1038/ncomms8100 article EN cc-by-nc-nd Nature Communications 2015-05-11

We show here that oxidative stress is involved in both sclerotial differentiation (SD) and aflatoxin B1 biosynthesis Aspergillus flavus. Specifically, we observed (i) regulates SD, as implied by its inhibition antioxidant modulators of reactive oxygen species thiol redox state, (ii) SD are comodulated stress. However, inhibited lower levels compared to shown comparison undifferentiated A. These same also characterize a mutant flavus strain, lacking the global regulatory gene veA. This unable...

10.1128/aem.01282-14 article EN Applied and Environmental Microbiology 2014-07-08

In 1965, James Lovelock published a general statement, based on thermodynamic chemical equilibrium principles, about how to detect extant or extinct life planet other than Earth. Nearly 50 years later, it is possible make such measurements with robotic missions as current and future Mars rovers, probes sample icy plumes of Enceladus Europa. We specific recommendation that certain characteristic patterns in the composition lipid hydrocarbons can only result from biological process, because...

10.1089/ast.2013.1134 article EN Astrobiology 2014-04-15

Metamorphosis (Gr. meta- "change" + morphe "form") as a biological process is generally attributed to subset of animals: most famously insects and amphibians, but some fish many marine invertebrates well. We held symposium at the 2006 Society for Integrative Comparative Biology (SICB) annual meeting in Orlando, FL (USA) discuss metamorphosis comparative context. Specifically, we considered possibility that term "metamorphosis" could be rightly applied non-animals well, including fungi,...

10.1093/icb/icl004 article EN Integrative and Comparative Biology 2006-06-07

The conditions and properties of hydrothermal vents fields are compared in terms their ability to support processes related the origin life. two sites can be considered as alternative hypotheses, from this comparison we propose a series experimental tests distinguish between them, focusing on those that involve concentration solutes, self-assembly membranous compartments, synthesis polymers. Key Word: Hydrothermal systems.

10.1089/ast.2015.1338 article EN Astrobiology 2015-12-01

The cytochrome d terminal oxidase complex is one of two oxidases in the aerobic respiratory chain Escherichia coli. enzyme located cytoplasmic membrane where it oxidizes ubiquinol-8 bilayer and reduces oxygen to water. Enzyme turnover coupled generation a proton-motive force, resulting electrogenic translocation across proton per electron passing through system. an alpha beta heterodimer containing four hemes. cyd locus, encoding both subunits, has previously been genetically mapped cloned....

10.1016/s0021-9258(18)37682-8 article EN cc-by Journal of Biological Chemistry 1988-09-01

Methods used to quantify the stress response in animals are vital tools many areas of biology. Here we describe a new method measuring response, which provides rapid results and can be field or laboratory. After stressful event, measure capacity circulating leukocytes produce respiratory burst vitro challenge by phorbol myristate acetate (PMA). During oxygen free radicals, level production measured directly as chemiluminescence. When PMA-stimulated whole blood chemiluminescence is after...

10.1113/eph8802571 article EN Experimental Physiology 2003-06-24

The aerobic respiratory chain of Escherichia coli contains two terminal oxidases which are differentially regulated. cytochrome o complex predominates under growth conditions high aeration, whereas the d when oxygen tension is low. Either oxidase will support growth. goal work presented in this paper was to identify genes required for expression functional form complex, other than encoding polypeptide components (cyd locus). A strain lacking (cyo mutant strain) mutagenized by using a...

10.1128/jb.169.5.2107-2112.1987 article EN Journal of Bacteriology 1987-05-01

An important factor that promotes bacterial and endotoxin translocation in obstructive jaundice is intestinal injury causes increased permeability. However, little known of the submicroscopic biochemical events leading to defects barrier. This study was undertaken investigate effect experimental on lipid peroxidation, protein oxidation thiol redox state.Rats were randomly divided into controls, sham operated bile duct ligated (BDL). After 10 days, barrier function assessed by measuring...

10.1046/j.0001-6772.2003.01229.x article EN Acta Physiologica Scandinavica 2004-01-23

The aa3-type cytochrome c oxidase from Rhodobacter sphaeroides is closely related to eukaryotic oxidases. Analysis of site-directed mutants identified the ligands heme a, a3, and CuB [Hosler et al. (1993) J. Bioenerg. Biomembr. 25, 121−133], which have been confirmed by high-resolution structures homologous oxidases [Iwata (1995) Nature 376, 660; Tsukihara Science 269, 1069; (1996) 272, 1136]. Since protons used form water originate inner side membrane, a3−CuB center located near outer...

10.1021/bi9606511 article EN Biochemistry 1996-01-01

To investigate the proposed mechanism by which intrauterine balloons achieve their tamponade effect of creating an 'intrauterine pressure that is greater than systemic arterial pressure'.To determine intraluminal pressures within a Bakri balloon during establishment positive 'tamponade test' in management postpartum haemorrhage. correlate these with contemporaneous readings blood recordings as documented from operating theatre anaesthetic charts.An obstetric unit (approximately 2400 births)...

10.1111/j.1471-0528.2009.02436.x article EN BJOG An International Journal of Obstetrics & Gynaecology 2009-11-27
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