A5090472796- Hormonal Regulation and Hypertension
- Dialysis and Renal Disease Management
- Vasculitis and related conditions
- Blood Pressure and Hypertension Studies
- Adrenal Hormones and Disorders
- Renal Diseases and Glomerulopathies
- Sodium Intake and Health
- Renin-Angiotensin System Studies
- Acute Kidney Injury Research
- Liver Disease Diagnosis and Treatment
- Lymphatic Disorders and Treatments
- Sarcoidosis and Beryllium Toxicity Research
- Chronic Lymphocytic Leukemia Research
- Pancreatic function and diabetes
- PARP inhibition in cancer therapy
- Iron Metabolism and Disorders
- Infective Endocarditis Diagnosis and Management
- Heat shock proteins research
- Sirtuins and Resveratrol in Medicine
- Heparin-Induced Thrombocytopenia and Thrombosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Muscle and Compartmental Disorders
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Biochemical Analysis and Sensing Techniques
- Regulation of Appetite and Obesity
Hamamatsu University School of Medicine
2008-2024
Hamari Chemicals (Japan)
2022-2024
Hamamatsu University
2008-2014
Fujieda Municipal General Hospital
2008
Patients with bacterial endocarditis often have renal complications. This report presents the case of an elderly man rapidly progressive glomerulonephritis (RPGN) associated subacute (SBE) due to Enterococcus faecalis infection. The patient was positive for anti-proteinase 3-antineutrophil cytoplasmic antibody (PR3-ANCA) and rheumatoid factor (RF) hypocomplementemia. Treatment SBE antibiotics surgical replacement affected valves resulted in improvement RPGN, disappearance PR3-ANCA RF,...
FreeStyle Libre has been approved for use in patients undergoing hemodialysis (HD) Japan, unlike Europe and the United States; however, evidence regarding its accuracy such is sparse. Forty-one participants with type 2 diabetes HD were recruited. The overall mean absolute relative difference 23.4% 33.9 mg/dL, respectively. Sensor glucose levels capillary significantly correlated (r = 0.858, P < .01), although sensor lower than levels. of became deteriorated days usage. percentage results...
High body mass index (BMI) is paradoxically associated with better outcomes in hemodialysis (HD) patients. This study aimed to examine whether serum creatinine (Cr), a marker of muscle mass, could modify the association between BMI, and mortality morbidity prevalent HD patients.A retrospective was conducted using nationwide database from registry Japanese Society for Dialysis Therapy. A total 119,099 patients were selected (age: 65±12 years; median time on HD: 5.6 male: 62%), we examined...
The goal of this study was to clarify the clinical manifestation hypercalcemia due hypoadrenalism in hemodialysis (HD) patients.We retrospectively analyzed characteristics five HD patients who had presented with adrenal insufficiency (age: 69 ± 7 [58-75] years old, time on HD: 13 11 [2-32] years). We conducted corticotropin-releasing hormone (CRH) and adrenocorticotropic (ACTH) stimulation tests. also examined serum bone turnover markers before after glucocorticoid replacement.All critical...
Renal vasoconstriction in generalized vasodilatation with blood pooling and the consequent reduction effective arterial volume is pathophysiological basis of liver cirrhosis (LC). Low levels fractional excretion sodium (FENa) are an marker hypoperfusion renal artery. However, relationship between FENa, LC severity life prognosis has not yet been elucidated.We examined 57 patients (39 men 18 women; mean age, 70.5 ± 8.8 years; underlying disease, type B hepatitis eight patients, C 37,...
Both hyperuricaemia and activation of the intrarenal renin-angiotensin system (RAS) play an important role in development hypertension renal damage. However, it has not been clear whether is associated with damage due to or RAS activation, as well their circadian rhythms.We recruited 43 chronic kidney disease (CKD) patients who did receive blockers antihyperuricaemic drugs, investigated relationship among serum uric acid (sUA) levels, rhythm urinary angiotensinogen (U-AGT) excretion levels...
This study examined the possible role of heat shock protein 27 (HSP27) expression in survival and regeneration proximal tubule (PT) cells after acute tubular injury. Rats were injected with a low (0.2 mg/kg) or high (4 dose uranyl acetate (UA) to induce renal Renal tissues immunostained for HSP27, focal adhesion kinase (FAK), bromodeoxyuridine (BrdU), stained by TUNEL method. Low-dose UA induced PT depletion three-quarters S3 segment. Here, became sporadically positive cytoplasmic HSP27...
Abstract Ghrelin is an orexigenic hormone mainly secreted by the stomach, and it decreases according to severity of gastric atrophy. has multiple favorable functions, including protein anabolism enhancement, anti‐inflammatory activity, cardiovascular protection, associated with survival in hemodialysis (HD) patients. Although plasma level role ghrelin may be different depending on gender, they have not been completely assessed HD We enrolled 80 (male/female: 51/29) maintenance An upper...
Abstract Background Adrenal insufficiency causes abnormal subjective symptoms such as general fatigue, signs hypotension, and abnormalities hypoglycemia leads to poor prognosis. However, all these are also observed in hemodialysis (HD) patients without adrenal insufficiency. The morphology of the glands HD with is unclear. Therefore, this study was performed clarify characteristics patients. Methods Seventeen who had test results indicating whose serum cortisol levels were less than 18 μg/dL...
A 73-year-old man with fever, renal insufficiency, and purpura was referred to our hospital be evaluated for insufficiency. Renal biopsy revealed acute chronic tubulointerstitial nephritis no laboratory findings of sarcoidosis or connective tissue disease. Low C4 levels elevation rheumatoid factors suggested cryoglobulinemia, which confirmed quantitative analysis. CD34 staining kidney peritubular capillaritis. Antineutrophil cytoplasmic antibodies were negative. The etiology capillaritis not...
A 60-year-old man with Waldenström's macroglobulinemia (WM) was admitted to our hospital for evaluation of rapid progressive renal deterioration despite 3 cycles oral melphalan and prednisolone (MP) therapy. Renal biopsy just before introducing hemodialysis revealed cast nephropathy severe tubulo-interstitial infiltration B lymphocytes. After 6 rituximab, cyclophosphamide, vincristine (R-COP) therapy, his function improved enough discontinue hemodialysis. This is a rare case WM-related...