A copper-catalyzed direct alkynylation of electron-deficient polyfluoroarenes with a wide range terminal alkynes is realized for the first time. The reaction proceeds under mild conditions O(2) as an oxidant.

Abstract A long‐standing challenge in Minisci reactions is achieving the arylation of heteroarenes by oxidative decarboxylation aromatic carboxylic acids. To address this challenge, silver‐catalyzed intermolecular reaction acids was developed. With an inexpensive silver salt as a catalyst, new enables variety to undergo decarboxylative coupling with electron‐deficient arenes or regardless position substituents on acid, thus eliminating need for ortho ‐substituted acids, which were limitation...

A versatile palladium catalyst system was developed to effect the decarboxylative Heck coupling of a variety arenecarboxylic acids with wide range olefins. The key obtaining efficient is use 1-adamatanecarboxylic acid as additive. Alkyl-substituted olefins coordinating groups were observed provide significantly improved regioselectivity compared other alkyl-substituted lacking groups, and acetate group allylic ester also tolerated in this reaction.

By using Pd(TFA)2/PCy3 as a catalyst, broad range of aromatic carboxylic acids, including heteroaromatic efficiently underwent decarboxylative coupling with an array polyfluoroarenes in the presence stoichiometric amount silver salts to generate biaryls. Silver were adjusted reactivity acids suppress protodecarboxylation and therefore improve cross-couplings. It was established that palladium complex containing PCy3 ligand capable catalyzing decarboxylation electron-rich promoted both...

Catalytic oxidative C-H bond functionalization reactions that proceed without requiring stoichiometric amounts of external oxidants or pre-functionalized oxidizing reagents could maximize the atom- and step-economy in chemical syntheses. However, such a transformation remains elusive. Here, we report photo-driven catalytic process enables decarboxylative trifluoromethylation (hetero)arenes with trifluoroacetic acid as trifluoromethyl source good yields presence an oxidant far lower than (for...

The palladium-catalyzed direct arylation of electron-deficient arenes that contain two or more fluorine groups with arylboronic acids was realized. key to achieving a broad substrate scope respect both polyfluorobenzenes and is the choice bases depending on acidities polyfluorobenzenes.

The ambient-temperature ortho C-H arylation of electron-deficient benzoic acids with aryl iodides has been achieved by using an Ac-Ile-OH-supported Pd catalyst. A wide range unactivated could cross-couple array in moderate to excellent yields. choice HFIP as a solvent is crucial realizing the mild arylation, and beneficial effect ligand on reaction likely stems from accelerated activation process improved catalyst lifetime.

Preparation and characterization of a series rodlike binuclear ruthenium polyynediyl complexes capped with redox-active organometallic fragments [(bph)(PPh3)2Ru]+ (bph=N-(benzoyl)-N'-(picolinylidene)-hydrazine) or [(Phtpy)(PPh3)2Ru]2+ (Phtpy=4'-phenyl-2,2':6',2' '-terpyridine) have been carried out. The length the molecular rods is extended by successive insertion 2,5-thiophene 1,4-phenylene spacers in bridging ligands. Oxidation thiophene-containing Ru2II,II induces isolation stable...

An unexpected coupling reaction of arene carboxylic acid with nitroethane via a combination decarboxylation and dehydrogenation is described. The method provides exclusively (E)-beta-nitrostyrenes.

Abstract A long‐standing challenge in Minisci reactions is achieving the arylation of heteroarenes by oxidative decarboxylation aromatic carboxylic acids. To address this challenge, silver‐catalyzed intermolecular reaction acids was developed. With an inexpensive silver salt as a catalyst, new enables variety to undergo decarboxylative coupling with electron‐deficient arenes or regardless position substituents on acid, thus eliminating need for ortho ‐substituted acids, which were limitation...

Three new cadmium coordination polymers with formula {[Cd(tdc)(bpe)(H2O)]·2H2O}n (1), [Cd(tdc)(bpp)]n (2), and [Cd(Htdc)2(bipy)]n (3) have been synthesized by hydrothermal reactions of acetate dihydrate 3,4-thiophenedicarboxylic acid (H2tdc) in the presence corresponding bis(pyridyl) ancillary ligands, namely, 1,2-bis(4-pyridyl)ethylene (bpe), 1,3-bis(4-pyridyl)propane (bpp), 4,4′-bipyridine (bipy), respectively. Structural analyses reveal that complex 1 exhibits a scarcely reported...

Herein, we report a ruthenium-catalyzed redox-neutral α-alkylation of unsaturated alcohols based on synergistic relay process involving olefin isomerization (chain walking) and umpolung hydrazone addition, which takes advantage the interaction between two rather inefficient individual reaction steps to enable an efficient overall process. This transformation shows compatibility hydrazone-type "carbanions" active protons in one-pot reaction, at same time achieves first Grignard-type...

A green and efficient protocol for the direct monofluorination of unactivated alkylarenes under visible-light irradiation has been developed, without any extraneous transition-metal catalysts or photosensitizers. This method is compatible with a broad spectrum functional groups, including carboxylic alcoholic scaffolds, mild reaction conditions. Gram-scale synthesis fluorine-containing pharmaceutical analogue was successfully executed, underscoring strategy's reliability practicality....

Five new two-dimensional (2D) lanthanide–organic frameworks with formula [Ln(Hbtca)2(OAc)(H2O)]n (Ln = Sm 1, Eu 2, Gd 3, Tb 4, Er 5; H2btca benzotriazole-5-carboxylic acid) have been synthesized by the solvothermal reactions of and corresponding lanthanide nitrate. X-ray diffraction analysis reveals that these complexes are isostructural each exhibits a 2D square-grid-type network constructed via Ln2(μ-CH3COO)2 dinuclear secondary building units (SBUs), in which Hbtca− anions adopt two...

A convenient synthesis of α-enaminones from cyclic ketones with anilines at room temperature <italic>via</italic> an oxygen-atom-transfer pathway oxoammonium salt.

Mother Nature has its own arts to build a vast number of carbohydrates; however, there is still lack tools for selective functionalization native carbohydrates through C─C bond formation. Such long-standing challenge the synthetic community lies into intrinsic problems related innate properties carbohydrates, e.g., ease oligomerization or polymerization, difficulty chemoselectivity control in presence multiple hydroxyl groups, great retain chiral centers during transformation, etc. Here, by...

Five new LnCPs decorated with H₂tdc and oxalate mixed ligands exhibit a 2D <bold>sql</bold> layer structure, then the layers are further linked by intermolecule hydrogen bonds to form 3D supramolecular network <bold>sxb</bold> topology.

Three three-dimensional (3D) supramolecular lanthanide complexes, {[Ln2(tdc)3(H2O)](H2O)2}n (Ln = La 1, Ce 2, Pr 3; H2tdc 3,4-thiophenedicarboxylic acid), have been synthesized by hydrothermal reactions of and the corresponding nitrate. Crystallographic data show that 1–3 are isomorphous crystallize in triclinic P space group. Each them exhibits an interesting pillared layered network comprising polymeric layers up-up-down-down (uudd) cyclic tetrameric water pillars. Furthermore, these...

Pd-catalyzed aerobic oxidative coupling of various benzoic acids with silyl enol esters proceeds via a combination decarboxylation sp(3) β-C-H bond activation to give Heck-type products. Mechanistic studies reveal this involves in situ generation olefin from oxidation enolate, followed by decarboxylative Heck coupling.

A Pd-catalyzed cyclization of α-bromo-propionanilides for the synthesis 3-substituted 2-oxindoles has been developed. This method features easy to prepare starting materials, broad substrate scope and good functional group tolerance.

Abstract Herein, we report a ruthenium‐catalyzed redox‐neutral α‐alkylation of unsaturated alcohols based on synergistic relay process involving olefin isomerization (chain walking) and umpolung hydrazone addition, which takes advantage the interaction between two rather inefficient individual reaction steps to enable an efficient overall process. This transformation shows compatibility hydrazone‐type “carbanions” active protons in one‐pot reaction, at same time achieves first Grignard‐type...

Herein, an oxidization reaction of enones with a CuII complex that leads to new type regioselective [3+2] cycloaddition is reported. Highly functionalized cyclopentenes and spirocyclic compounds are obtained in moderate-to-good yields. This occurred through the formation γ-enone radicals, providing rarely explored reactivity pattern for enones.

Article Β. H. Vos, Rechtsgeschiedkundige beschouwingen over het Romeinsche huwelijk J. van Meurs, Rechtsgedingen bepaalde goederen in oud-Helleense Rechten. Utrechtsch proefschrift was published on August 1, 1915 the journal Zeitschrift der Savigny-Stiftung für Rechtsgeschichte: Romanistische Abteilung (volume 36, issue 1).