A5101747370- Immune Cell Function and Interaction
- IL-33, ST2, and ILC Pathways
- Eosinophilic Esophagitis
- Respiratory viral infections research
- Growth Hormone and Insulin-like Growth Factors
- Thyroid Disorders and Treatments
- Pediatric health and respiratory diseases
- Venous Thromboembolism Diagnosis and Management
- Cancer-related Molecular Pathways
- Immune cells in cancer
- Inflammatory Biomarkers in Disease Prognosis
- Renal and Vascular Pathologies
- AI in cancer detection
- Cancer Immunotherapy and Biomarkers
- Histone Deacetylase Inhibitors Research
- Digital Radiography and Breast Imaging
- Healthcare professionals’ stress and burnout
- Silicon Carbide Semiconductor Technologies
- Global Cancer Incidence and Screening
- Advanced ceramic materials synthesis
- Neuroscience of respiration and sleep
- Copper Interconnects and Reliability
- COVID-19 and Mental Health
- Thyroid Cancer Diagnosis and Treatment
- Health disparities and outcomes
China Medical University
2016-2024
Jinan University
2024
Southern University of Science and Technology
2024
Xuzhou No.1 People's Hospital
2024
Xuzhou Medical College
2024
Jiangsu University
2024
First People's Hospital of Kunshan
2024
First Affiliated Hospital of Kunming Medical University
2023
Kunming Medical University
2023
The thyroid gland exhibits a subtle interconnection with the lungs. We further investigated correlation between hormone sensitivity and lung function in euthyroid individuals.
The relationship between thyroid hormone sensitivity and albuminuria remains unclear. We aimed to investigate the association risk of in a euthyroid population. This cross-sectional study included 7634 adults collected from National Health Nutrition Examination Survey (NHANES) 2007 2012. Central hormones was evaluated using thyroid-stimulating index (TSHI), thyrotrophic thyroxine resistance (TT4RI), feedback quantile-based (TFQI). Peripheral measured free triiodothyronine/free (FT3/FT4)...
The present study explored the anti-tumor effects of chidamide plus oxaliplatin on colorectal cancer (CRC) and examined its underlying mechanism.First, Combination Index (CI) was evaluated via CCK-8 assay. Second, monotherapy combined treatment cell proliferation, invasion, migration, apoptosis were detected. Third, whole-transcriptome RNA sequencing (RNA-seq) performed to seek potential targeted gene by which exerted effects. Fourth, validation signal pathway it regulated performed....
Aim: How respiratory syncytial virus (RSV) influences the development of ovalbumin (OVA)-induced asthma remains elusive. As potent T helper (Th)2 cytokine producers, group 2 innate lymphoid cells (ILC2s) are known to serve important functions in pathogenesis allergic inflammation. However, how RSV infection affects immunity, especially with regard function ILC2s OVA-induced airway inflammation, is largely unknown. Materials & methods: was used infect adult BALB/c mice intranasally prior...
Aim: Type 2 cytokine production during respiratory virus infection is considered to be linked with asthma exacerbation. As potent Th2 producers, natural helper (NH) cells play a key role in influenza virus-induced airway hyper-responsiveness. However, it unclear whether NH contribute syncytial (RSV)-induced inflammation, and how the profile changed RSV infection. Methods: BALB/c mice were infected intranasally RSV. The number of lungs was detected by flow cytometry. expression mRNAs...
Aim: To investigate whether and how CD4+ T cells contribute to ILC2 activation during respiratory syncytial virus (RSV) infection. Methods: The methods of flow cytometry, quantitative PCR ELISA were used in the present study. Results: Depletion diminished numbers lung ILC2s as well their ability produce type 2 cytokines. cell-mediated is related IL-2. main cellular source IL-2 was cells. decreased levels lungs RSV-infected mice. can directly stimulate proliferation promote Treatment mice...
Age at primary infection with respiratory syncytial virus (RSV) is a crucial factor in determining the outcome of reinfection. However, how neonatal RSV affects immune system and renders host more susceptible to reinfection later life poorly understood. In present study, by using BALB/c mice that were first infected as neonates, role γδ T cells development airway inflammation during adulthood was investigated. We found resulted an aggravated infiltration mononuclear bronchoalveolar lavage...
Objective: To investigate the value of mesenteric CTA combined with D-dimer (DD) level and inflammatory factor changes in evaluating severity artery embolism.
 Methods: This is a retrospective study. The imaging data levels plasma DD factors 120 patients embolism confirmed by DSA or surgery Baoding No.1 Central Hospital were analyzed retrospectively from January 2021 to December 2022. coincidence rate alone results was compared analyzed. specificity, sensitivity accuracy diagnosing...
Type 2 innate lymphoid cells (ILC2s) are recently identified members of the cell (ILC) family. These capable producing Th2-type cytokines such as IL-5 and IL-13 in response to epithelial cell-derived IL-25 IL-33 play critical roles allergic diseases bronchial asthma. Further investigations on ILC2s will enhance better understanding type immune responses may provide new strategies for treatment In this review, we focus origin, location biological function well their possible pathogenesis...
Objective To investigate the role of CD4+ T cells in airway inflammation induced by respiratory syncytial virus (RSV) infection. Methods Animal models acute RSV infection were established. Lung tissues stained with hematoxylin and eosin (HE) to observe histopathological changes. Total number secreting Th1/Th2 cytokines (IFN-γ, IL-4, IL-5 IL-13) spleen detected flow cytometry. Adoptive transfer was performed identify RSV-induced inflammation. Results RSV increased total splenic...