A5109458353- Tissue Engineering and Regenerative Medicine
- Protease and Inhibitor Mechanisms
- Electrospun Nanofibers in Biomedical Applications
- Congenital heart defects research
- Mesenchymal stem cell research
- Cardiac Fibrosis and Remodeling
- Angiogenesis and VEGF in Cancer
- Peptidase Inhibition and Analysis
- Biomarkers in Disease Mechanisms
- Cell Adhesion Molecules Research
- Cardiovascular Disease and Adiposity
- Eicosanoids and Hypertension Pharmacology
- Stress Responses and Cortisol
- Retinal Diseases and Treatments
- Connective tissue disorders research
- Enzyme Production and Characterization
- Neurological Disorders and Treatments
- Viral Infectious Diseases and Gene Expression in Insects
- Adipokines, Inflammation, and Metabolic Diseases
- Nuclear Receptors and Signaling
- Cardiac Structural Anomalies and Repair
- Connective Tissue Growth Factor Research
- Photoreceptor and optogenetics research
- Advanced Chemical Sensor Technologies
- Photochemistry and Electron Transfer Studies
Siberian Federal University
2024
National Medical Research Center of Cardiology
2018-2023
Institute of Experimental Cardiology
2006-2022
Lomonosov Moscow State University
2010-2022
Russian Academy of Sciences
2020
Moscow State University
2018-2020
Ministry of Health of the Russian Federation
1998-2014
Ministry of Health
1998
Genetika
1990
The aim of the investigation was to study effect 2-ethyl-6-methyl-3-hydroxypyridine malate (Ethoxidol) on concentration oxidative stress metabolites in patients with chronic heart failure (CHF) and hypertension.126 FC I-III CHF have been examined. In addition their individual therapy these received intravenous infusions Ethoxidol. Blood content 2,3-diphosphoglycerate (2,3-DPG), oxygen tension (рО2), pH, total peroxides, lactate, aldosterone were identified. 2,3-DPG levels (g/L erythrocytes)...
Proliferation, subsequent migration to the damaged area, differentiation into appropriate cell types, and/or secretion of biologically active molecules and extracellular vesicles are important processes that underlie involvement stem/progenitor cells in repair regeneration tissues organs. All these functions regulated through interaction between stem microenvironment tissue niches control direct cell-cell interactions, production matrix, release vesicles, growth factors, cytokines,...
Now, great interest is connected with application of the cells received directly from a myocardium as tool for stimulation angiogenesis and reparative processes in heart. The aim present research studying angiogenic properties vitro vivo c-kit+-cells, obtained hearts small rodents. work was performed on male C57BL/6 mice Wistar rats. study used methods cytofluorimetry, immuno-fluorescent staining, models myocardial infarction subcutaneous Matrigel™. It shown, that after acute c-kit+...
A new trend in modern experimental cardiology is the development of approaches to correction reparation after myocardial infarction (MI) with use specific effects on immune cells. One main targets for such interventions process macrophage's polarization zone. Proinflammatory M1-macrophages contribute hampered repair, contrast M2-macrophages that promote regeneration. Currently, there are two ways targeted delivery agents necessary macrophage reprogramming - inlipoid and inglycan-encapsulated...