A5044853661- Parvovirus B19 Infection Studies
- Pregnancy and preeclampsia studies
- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Blood groups and transfusion
- Congenital Anomalies and Fetal Surgery
- Fetal and Pediatric Neurological Disorders
- Ectopic Pregnancy Diagnosis and Management
- Gestational Diabetes Research and Management
- Gestational Trophoblastic Disease Studies
- Immunodeficiency and Autoimmune Disorders
- Hemoglobinopathies and Related Disorders
- Congenital Diaphragmatic Hernia Studies
- Cardiovascular Issues in Pregnancy
- Maternal and fetal healthcare
- Urological Disorders and Treatments
- Herpesvirus Infections and Treatments
- Thyroid Disorders and Treatments
- Preterm Birth and Chorioamnionitis
- Homicide, Infanticide, and Child Abuse
- Blood disorders and treatments
- Erythrocyte Function and Pathophysiology
- Cancer Genomics and Diagnostics
- Neonatal Health and Biochemistry
- Renal and related cancers
Universitat Autònoma de Barcelona
2009-2025
Hebron University
2021-2025
Society for Maternal-Fetal Medicine
2023
Instituto de Salud Carlos III
2011-2021
Hospital de Cruces
2021
Hospital Sant Joan de Déu Barcelona
2021
Parc Sanitari Sant Joan de Déu
2021
Vall d'Hebron Hospital Universitari
2011-2021
Abstract Placental mesenchymal dysplasia (PMD) is a rare placental pathology that may be associated with Beckwith–Wiedemann features in the fetus and due to presence of an androgenetic cell line. Many reported PMD cases describe biparental isodisomic The proposed mechanism formation by fertilization haploid ovum sperm duplication male pronucleus. We present case evidence participation three different gametes, one two spermatozoa, which led androgenetic/biparental chimera (ABC) fetal lines...
ABSTRACT Objectives To describe the outcome of patients with twin‐to‐twin transfusion syndrome and cervical length ≤ 25 mm, treated laser an Arabin pessary. Methods Retrospective analysis a consecutive series all cases severe who underwent surgery: group above mm (group A) two groups had or less prior to procedure. The first 8 B) were managed expectantly next pessary inserted immediately after surgery C). Gestational age at birth was primary outcome. secondary composite one encompassing...
Abstract Umbilical cord amniotic bands occur in approximately 10% of cases band syndrome and are a well‐known cause fetal death. An unexpected encircling the umbilical was diagnosed during fetoscopic procedure to release leg constriction. Both were released fetoscopically using YAG laser. We report first case an involving prenatally. Copyright © 2009 ISUOG. Published by John Wiley & Sons, Ltd.
The risk of pre-eclampsia (PE) increases in twin pregnancies, especially when assisted reproduction technologies (ART) are used. aim this study was to assess angiogenic/anti-angiogenic factors maternal serum the first trimester pregnancies and establish if mode conception influences angiogenic status. This prospective enrolled women with (n = 61) singleton 50) pregnancies. Dichorionic were divided into two groups according their conception. Singleton used as control group. Soluble fms-like...
Different strategies have been designed for clinical implementation of cell-free DNA (cfDNA) testing. We aimed to evaluate the performance a contingent strategy based on conventional screening and offering cfDNA intermediate-risk group, trisomies 21, 18 13. Secondary objectives were assess uptake in women with intermediate-risk, testing, preferences pregnant intermediate risk. Prospective observational pilot study between February 2016 March 2017. Singleton pregnancies known outcome included...
ABSTRACT Objectives To compare the ability of first‐trimester combined screening for pre‐eclampsia (PE) to predict early‐onset and preterm PE when pregnancy‐associated plasma protein‐A (PAPP‐A) placental growth factor (PlGF) were assessed before vs after 11 weeks' gestation. Methods This was a secondary analysis prospective cohort study singleton pregnancies undergoing routine conducted at Vall d'Hebron University Hospital, Barcelona, Spain, between October 2015 September 2017. Demographic...
Prenatal ultrasound study allows the detection of fetal malformations. Intrauterine interventions are now contemplated to correct, or interfere with, natural history these anomalies. Minimally invasive techniques, such as so-called "Fetendo" (fetal endoscopy), therapeutic possibilities.From 2002 2007, 205 fetoscopies were performed in our hospital's surgery program. Fetoscopic carried out under epidural anesthesia, accessing uterine cavity with a fetoscope containing 1.2-mm telescope....
Abstract Background The aims of this study were to determine the prevalence different anti-erythrocytic alloantibodies, describe pregnancy outcomes according a low-risk and high-risk classification for fetal anemia factors that influence adverse perinatal outcomes. Methods This retrospective observational included women referred our center following identification maternal alloantibodies between 2002 2017. Pregnancies classified as high risk in cases with clinically significant antibodies,...
<b><i>Background:</i></b> Preeclampsia (PE) and intrauterine growth restriction (IUGR) are major causes of maternal perinatal morbidity mortality. Previous studies have shown that intervention with low-dose aspirin resulted in a reduction the occurrence preterm PE. However, no data currently available on effect low-molecular-weight heparin (LMWH) for prevention pregnancy complications women enrolled at first trimester screening....
To evaluate the diagnostic accuracy of different beta-human chorionic gonadotrophin (ß-hCG) levels measurement, for predicting success medical treatment in cases diagnosed as tubal ectopic pregnancy (TEP).Five-year prospective observational study.Prenatal Diagnosis Unit, Vall d'Hebron University Hospital - Barcelona.TEP fulfilling criteria with Methotrexate.ß-hCG were measured on d 0, 4 and 7 treatment. Results compared by non-parametrical tests. A ROC curve was plotted to define cut-off...
Pre-eclampsia (PE) and small for gestational age (SGA) can be predicted from the first trimester. The most widely used algorithm worldwide is Fetal Medicine Foundation (FMF) algorithm. recently described Gaussian has reported excellent results although it unlikely to externally validated. Therefore, as an alternative approach, we compared predictive accuracy PE SGA of FMF algorithms.Secondary analysis a prospective cohort study was conducted at Vall d'Hebron University Hospital (Barcelona)...
Introduction Congenital cytomegalovirus (cCMV) is the leading cause of non-genetic sensorineural hearing loss and one main causes neurological disability. Despite this, no universal screening programme for cCMV has been implemented in Spain. A recent study shown that early treatment with valaciclovir, initiated first trimester before onset signs fetus, reduces risk fetal infection. This finding favours implementation a cCMV. The aim this to evaluate performance during pregnancy primary care...
Abstract Background This study aimed to describe the perinatal outcome and central nervous system (CNS) anomalies in fetuses undergoing red blood cell (RBC) intrauterine transfusion (IUT). Methods Materials was an observational single‐cohort carried out at Vall d'Hebron University Hospital Barcelona, Spain, between 2002 2018 women RBC IUT for suspected fetal anemia. Primary outcomes were adverse (intrauterine or neonatal death termination of pregnancy [TOP]), prenatal postnatal CNS...
Objective: To compare the predictive accuracy of Gaussian and FMF algorithms for preeclampsia (PE) small gestational age fetuses (SGA). Design: Secondary analysis a prospective cohort study. Setting: Tertiary referral hospital. Population: 2641 singleton pregnancies attending routine first-trimester scan from October 2015 to September 2017. Methods: Maternal characteristics, mean arterial blood pressure (MAP), uterine artery pulsatility index (UtAPI) were recorded at scan. Serum placental...
To evaluate risk factors for intrauterine fetal death (IUFD) in a cohort of monochorionic twins affected by selective growth restriction (sIUGR). Retrospective study 92 sIUGR followed at Vall d'Hebron Hospital during the last 8 years. was defined as fetuses with an estimated weight < 10th percentile or discordance ≥ 30%. Twin to twin transfusion syndrome, congenital anomalies IUFD 16 weeks were excluded. All classified according presentation early (⩽ 26 weeks) late (> and umbilical artery...
To compare the rate of pregnancy loss between twin pregnancies undergoing a genetic amniocentesis (AC) and control group with similar characteristics. Prospective observational study on population referred to our prenatal diagnosis unit for screening from 1990 2010. Those cases submitted AC were compared those without indication procedure. Primary outcome was within four weeks after Secondary included before 24 weeks, neonatal morbidity, gestational age at delivery birth weight. Maternal...
Estudiar el grado de aceptación la amniocentesis y sus diferencias en función indicación entre las pacientes con riesgo secundario a edad al cribado bioquímico Se incluyó gestantes referidas unidad diagnóstico prenatal para estudio cariotipo fetal durante un período 7 años. Las fueron clasificadas dos grupos según indicación: grupo I (edad) II (cribado indicativo) 9.227 mujeres: 4.859 materna 4.368 por bioquímico. Rechazaron 176 (el 3,62%; intervalo confianza (IC) del 95%, 3,35–3,89%) 152...
(Abstracted from Fetal Diagn Ther 2020;47:824–833) Preeclampsia (PE) and intrauterine growth restriction (IUGR) are among the many causes of maternal perinatal morbidity mortality. Prior studies have shown that introduction low-dose aspirin before 16 weeks gestation can lead to a reduction in prevalence preterm PE IUGR.
Hydrops fetalis is an excessive accumulation of fetal fluid. 85% hydrops non-immune origin and 4% have a monogenic syndrome origin. A 30-year-old primigravida with dichorionic-diamniotic twin pregnancy after in vitro fertilisation consanguineous marriage was diagnosed one the twins at 12-week scan. Immune (IH) excluded. Invasive test offered amniocentesis performed. Quantitative Fluorescence Polymerase Chain Reaction (QF-PCR), Comparative Genome Hybridisation (CGH) array infection studies...