- Kawasaki Disease and Coronary Complications
- Mechanical Circulatory Support Devices
- Congenital Heart Disease Studies
- Coronary Artery Anomalies
- Pneumonia and Respiratory Infections
- Aortic Disease and Treatment Approaches
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Family and Disability Support Research
- Neonatal Respiratory Health Research
- Allergic Rhinitis and Sensitization
- Connective tissue disorders research
- Asthma and respiratory diseases
- Cardiovascular Syncope and Autonomic Disorders
- Pediatric Pain Management Techniques
- Metabolism and Genetic Disorders
- Adolescent and Pediatric Healthcare
- Cardiovascular Function and Risk Factors
- Legionella and Acanthamoeba research
- Complement system in diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Cardiovascular Conditions and Treatments
- Pharmacy and Medical Practices
- Parathyroid Disorders and Treatments
- Hepatitis Viruses Studies and Epidemiology
Nagoya Central Hospital
2025
Higashi Nagoya National Hospital
2021-2023
Japanese Red Cross Nagoya Daini Hospital
1995-2018
Red Cross Hospital
1987-2003
Kurume University
2000
Abstract In order to evaluate the contribution of FBN1, FBN2, TGFBR1 , and TGFBR2 mutations Marfan syndrome (MFS) phenotype, four genes were analyzed by direct sequencing in 49 patients with MFS or suspected as a cohort study. A total 27 FBN1 (22 novel) (55%, 27/49), 1 novel mutation (2%, 1/49), 2 recurrent (4%, 2/49) identified. No FBN2 was found. Three either abnormality did not fulfill Ghent criteria, but expressed some overlapping features Loeys–Dietz (LDS). remaining 19 patients, show...
Abstract Objectives: The early administration of immunoglobulin in Kawasaki disease occasionally results treatment failure. However, whether this is because severe cases are diagnosed and treated or due to other factors remains unclear. In study, we examined the timing initial resistance classified by severity illness. Methods: This study was a single-hospital, retrospective cohort 608 patients who received within 4 (Early-treatment group, n=225) between 5 7 days (Late-treatment n=383)...
ABSTRACT We report the first case of neonatal Legionnaires' disease associated with water birth in a spa bath at home. Legionella pneumophila serogroup 6 was detected from postmortem lung tissue.
In Nagoya city, Japan, rotavirus (RV) vaccination has been available since 2011 with estimated coverage reaching 92% by 2015 after the introduction of a public subsidy in 2012. This study assessed impact on RV gastroenteritis (RVGE) burden children aged <5 years old (y) comparing RVGE hospitalizations and outpatient visits during pre-vaccination (2007-2011), transition (2011-2012) subsidization (2012-2016) periods.All y from 2 administrative districts city were identified hospital-based...
To support children with chronic diseases, reference values to measure developmental changes in self-perception and self-esteem are considered a useful yardstick. develop self-perceived competence Japanese children, the Children’s Perceived Competence Scale (CPCS) was administered 768 of elementary school grade 1 (6 years) 6 (11 at four public schools Japan, from November December 2012. After excluding 74 diseases and/or incomplete responses, 694 were included. CPCS measures children’s...
小児救急医療においては初期・2次救急への対応策が取られてきたが,平成21年度からは厚生労働省による検討会が持たれ,3次救急への対応が検討されるようになった。今回の調査では9割近くの救命救急センターは,常に小児救急医療に対応していたが,施設の特徴により受診数や入院数,入院病名には差異が見られた。小児の年間ICU入院数は平均19.3名で,CPA数平均4.0名,死亡退院数平均2.7名が示すように重篤患者は少なかった。小児の利用可能なICUは20.3%にあったが,そのうちで救命救急センター内にあるものが7.2% で,病床数は平均1.6床であった。時間外における小児科医の対応は72%で可能であったが,救命救急センターの常勤小児科医によるものは15%であった。救命救急センターは施設間に偏りがあるものの小児の3次救急に可能な範囲で対応していた。小児の内因性疾患に対応可能な施設は,小児科医と救急医が協力し,重篤小児の超急性期の治療を進めていく必要がある。
We aimed to evaluate self-perceived competence and self-esteem of primary school children with autism spectrum disorder (ASD) in Japan compare those other chronic physical diseases healthy controls.Data were collected from 227 children: ASD (N.=91), nephrotic syndrome (NS) (N.=52) asthma (N.=84), using Children's Perceived Competence Scale (CPCS) 2012-2014. CPCS measures perceived cognitive, social domains, a general self-worth domain as self-esteem.Scores the group lower than all groups...
A 14-year-old girl, having mental and growth retardation with end stage renal disease, was affected by a stroke-like attack. The attack associated transient low density areas at both sides of the parietal portion on head CT. Lactic acidosis, hypertrophic cardiomyopathy, angina pectoris-like attacks, hypertension hyperparathyroidism were also observed they supposedly due to mitochondrial cytopathy. No morphological or biochemical abnormalities found respiratory chain. However, muscle...
First objects were households of 12 children with asthma (3-12 years) that Dermatophagoides farinae (Der f) specific IgE value was more than 17.5PRU/ml and normal children. The staffs health center visited the 24 once a month during five months gathered dust by cleaner Dust Sampler. Sampler is maked double filters 16 mesh (1000μ) 2000 (74μ) around shape 5cm in diameter. antigen house mite measured antibodies sandwich ELISA method monoclonal antibody Checker, cleaned regularly determined...
Abstract Background Persistent low‐grade fever has been observed in some patients during intravenous immunoglobulin (IVIG) therapy for Kawasaki disease (KD); however, smoldering (SF) not previously reported with KD. This study aimed to clarify the clinical characteristics of SF Methods A single‐center retrospective cohort study, which included a total 621 who received IVIG therapy, was conducted. Patients 37.5–38°C lasting ≥3 days after 2 initial‐IVIG were defined as group. divided into four...
Abstract Background The purpose of this study was to predict which patients would require plasma exchange therapy (PEX) using laboratory findings during intravenous immunoglobulin (IVIG) in Kawasaki disease. Methods A retrospective, single‐center, cohort conducted. Of the 621 IVIG‐treated patients, 166 who received a second IVIG dose on day after initiation were included. endpoint PEX. Participants divided into two groups: 10 PEX and 156 did not. variables C‐reactive protein (CRP), white...
2カ月男児の発熱に対して解熱剤 (アセトアミノフェンおよびメフェナム酸) が投与された。その数十分後に痙攣,意識障害が出現し,中枢神経,肝臓,腎臓,骨格筋を傷害した多臓器機能障害症候群 (以下MODS) を発症した症例を経験した。児は,全血漿交換療法を用いた集中治療管理により約10日間の経過で回復し,眼球運動異常を後遺症として残した。本症例では非常に速やかに臨床症状が改善しており,原因としては脳炎,脳症というよりは解熱剤投与による末梢血管拡張および体血圧低下によりMODSが引き起こされたと考えた。乳児期早期および新生児期での発熱に対し解熱剤投与は慎重にすべきである。
Case 1 is a 5-year-2-month-old girl. She was admitted to another hospital for an asthma attack 3 months ago. Because of respiratory failure she then moved our hospital, and immediately mechanically ventilated. On the 3rd day developed subcutaneous emphysema, administered isoflurane. After 23 hours, this therapy discontinued endotracheal tube removed on 4th day. 2 11-year-old girl who had been treated with MDI (metered dose inhaler) fenoterol regular inhalation orciprenaline. brought in...