Jiakai Zhang

ORCID: 0000-0001-9767-8333
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About
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Research Areas
  • Extraction and Separation Processes
  • Geochemistry and Elemental Analysis
  • Antenna Design and Analysis
  • Phase Equilibria and Thermodynamics
  • Advanced Antenna and Metasurface Technologies
  • Metamaterials and Metasurfaces Applications
  • Ubiquitin and proteasome pathways
  • Recycling and Waste Management Techniques
  • Advancements in Battery Materials
  • Advanced Battery Technologies Research
  • Radioactive element chemistry and processing
  • Thermodynamic and Exergetic Analyses of Power and Cooling Systems
  • Advanced Thermodynamic Systems and Engines
  • Cancer-related gene regulation
  • Environmental Impact and Sustainability
  • Advanced NMR Techniques and Applications
  • Quantum optics and atomic interactions
  • Cancer, Lipids, and Metabolism
  • Atomic and Subatomic Physics Research
  • Catalytic Processes in Materials Science
  • Ammonia Synthesis and Nitrogen Reduction
  • Multiple Myeloma Research and Treatments
  • Ferroptosis and cancer prognosis
  • Cancer, Hypoxia, and Metabolism
  • Protein Degradation and Inhibitors

Qingdao University
2024

Central China Normal University
2024

First Affiliated Hospital of Zhengzhou University
2016-2024

Shanghai University of Electric Power
2022-2024

Zhengzhou University
2017-2024

PLA Electronic Engineering Institute
2024

First Affiliated Hospital of Hebei Medical University
2024

Hebei Medical University
2024

University of Toronto
2018-2023

Northwestern Polytechnical University
2014-2020

The long-term exposure of skin wounds, especially for those chronic is commonly accompanied with the bacterial infection, which further holds back wound healing process. Therefore, it's urgently required to develop innovative dressings both antibacterial property and healing-promoting function. In this study, a series novel hydrogel constructed polyasparthydrazide (PAHy) nanofibers different concentrations in-situ synthesized silver nanoparticles (AgNPs) were designed prepared. It was found...

10.1016/j.matdes.2024.112818 article EN cc-by-nc-nd Materials & Design 2024-02-29

A novel polarization-insensitive metasurface with angular stability for ultra-broadband (from 7 to 12 GHz) backscatter radar cross section (RCS) reduction is investigated. The proposed composed of carefully arranged unit cells spatially varied dimension, which can diffuse reflection uniformly and avoid the in specular direction. sample fabricated tested validate RCS behavior predicted by full-wave simulation software ANSYS HFSS. more than 10 dB within entire X-band observed, indicating our...

10.1109/lawp.2015.2443853 article EN IEEE Antennas and Wireless Propagation Letters 2015-06-10

There is a global need for efficient and environmentally sustainable processes to close the life cycle loop of waste electrical electronic equipment (WEEE) through recycling. Conventional WEEE recycling are based upon pyrometallurgy or hydrometallurgy. The former energy-intensive generates greenhouse gas (GHG) emissions, while latter relies on large volumes acids organic solvents, thus generating hazardous wastes. Here, novel "aeriometallurgical" process was developed recycle critical rare...

10.1021/acssuschemeng.8b03992 article EN ACS Sustainable Chemistry & Engineering 2018-10-24

Mounting evidence has revealed that the interactions and dynamic alterations among immune cells are critical in shaping tumor microenvironment ultimately map onto heterogeneous clinical outcomes. Currently, underlying significance of cell evolutions remains largely unexplored hepatocellular carcinoma (HCC). A total 3,817 1,750 HCC patients 15 independent public datasets were retrieved. The Seurat Monocle algorithms used to depict T evolution, nonnegative matrix factorization (NMF) was...

10.3389/fimmu.2022.964190 article EN cc-by Frontiers in Immunology 2022-07-27

Quantum electronics operating in the microwave domain are burgeoning and becoming essential building blocks of quantum computers, sensors, communication devices. However, field has long been dominated by need for cryogenic conditions to maintain delicate characteristics. Here, a solid-state hybrid system, constituted photo-excited pentacene triplet spin ensemble coupled dielectric resonator, is reported first time capable both coherent amplification oscillation at X band via masing process...

10.1002/advs.202401904 article EN cc-by Advanced Science 2024-07-15

Supercritical fluid extraction (SCFE) is gaining significant interest as a green technology for the recycling of end-of-life waste electrical and electronic equipment (WEEE). Neodymium iron boron (NdFeB) magnets, which contain large quantities critical rare-earth elements such neodymium, praseodymium, dysprosium, are widely used in wind turbines electric/hybrid vehicles. Hence, they considered promising secondary resource these when reach their end-of-life. Previously, SCFE process was...

10.1021/acs.inorgchem.2c04508 article EN Inorganic Chemistry 2023-05-08

Bromodomain and Extra-Terminal Domain (BET) inhibitors, such as JQ1 have emerged novel drug candidates are being enthusiastically pursued in clinical trials for the treatment of cancer. However, many solid cancers resistance to BET inhibitors. To explore methods improving therapeutic potential we investigated combinational activity with Oridonin, a bioactive molecules derived from Traditional Chinese Medicine hepatocellular carcinoma (HCC) cells. Our results showed that Oridonin...

10.18632/oncotarget.21880 article EN Oncotarget 2017-10-16

Abstract Astaxanthin (ASX) is an oxygen‐containing non‐vitamin A carotenoid pigment. However, the role of ASX in autoimmune hepatitis (AIH) remains unclear. In this study, a mouse model AIH established induced by concanavalin (ConA). Mass cytometry and single‐cell RNA sequencing (scRNA‐seq) are used to analyze potential regulating immune microenvironment AIH. treatment effectively alleviated liver damage ConA downregulated pro‐inflammatory cytokines production mice. scRNA‐seq analyses...

10.1002/advs.202403148 article EN cc-by Advanced Science 2024-06-14

In this work, a series of novel arylamide derivatives containing piperazine moiety were designed and synthesised as tubulin polymerisation inhibitors. Among 25 target compounds, compound 16f (MY-1121) exhibited low nanomolar IC50 values ranging from 0.089 to 0.238 μM against nine human cancer cells. Its inhibitory effects on liver cells particularly evident with 89.42 91.62 nM for SMMC-7721 HuH-7 cells, respectively. Further mechanism studies demonstrated that could bind the colchicine...

10.1080/14756366.2023.2237701 article EN cc-by-nc Journal of Enzyme Inhibition and Medicinal Chemistry 2023-07-24

Kruppel-like factor 6 (KLF6) as a novel tumor suppressive gene participates in multiple biological behaviors and plays an important role regulating cell growth invasion. However, the functions of KLF6 hepatocellular carcinoma (HCC) remain poorly understood. The expression level was examined by immunohistochemical assay human HCC tissues, KLF6-overexpressed cells (SMCC-7721 HepG2) were used for evaluating proliferation invasion MTT Transwell assays. A subcutaneous model established assessing...

10.1177/0394632016655171 article EN International Journal of Immunopathology and Pharmacology 2016-08-11

In order to maximize the power spectrum utilization (PSU) while satisfying Federal Communications Commission (FCC) emission mask, an improved two-stage ultra-wideband (UWB) pulse shaping method based on Gaussian derivatives is presented. Firstly, sub-pulses are designed by optimal combination of over specific sub bands with condition maximizing PSU allowed mask. Secondly, full band UWB shaped outputs parallel band-pass filters (BPFs) bank pulses as inputs these BPFs. Simulation results show...

10.1049/cp.2011.0925 article EN IET International Communication Conference on Wireless Mobile and Computing (CCWMC 2009) 2011-01-01

Abstract This paper presents a novel dual-band (DB) dual-polarized (DP) shared aperture antenna with high isolation by using combination of microstrip dipoles and dielectric resonator antennas (DRAs) for S C bands, respectively. In the band, two sets proximity coupled stacked which crossed at center are employed to achieve dual-linear polarization (DLP) obtain desired bandwidth (BW), isolation, pure polarization. The rectangle DRA hybrid feed is selected as band element its advantages small...

10.1017/s1759078719001454 article EN International Journal of Microwave and Wireless Technologies 2020-05-04

A novel polarization insensitive metasurface with over 25 dB monostatic radar cross-section (RCS) reduction is introduced. The proposed comprised of carefully arranged unit cells spatially varied dimension, which enables approximate uniform diffusion incoming electromagnetic (EM) energy and reduces the threat from bistatic system. An iterative fast Fourier transform (FFT) method for conventional antenna array pattern synthesis innovatively applied to find best cell geometry parameter...

10.1142/s021798491650233x article EN Modern Physics Letters B 2016-07-01

A novel polarization-independent Mu-negative metamaterial with broad bandwidth named fan-shaped structure, composed of periodically arranged capacity-loaded patches symmetrically printed on the both side a FR4 substrate, is theoretically and numerically investigated in this paper. First, effective constitutive parameters are retrieved from computed scattering found having negative permeability characteristic frequency range 6.86–9.46 GHz, which much wider than conventional split-ring...

10.1080/09500340.2014.948513 article EN Journal of Modern Optics 2014-08-20
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