A5076452432- Peripheral Nerve Disorders
- Ocular Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Streptococcal Infections and Treatments
- Connective tissue disorders research
- melanin and skin pigmentation
- Neurogenetic and Muscular Disorders Research
- Dermatological and Skeletal Disorders
- Orthopedic Surgery and Rehabilitation
- Thyroid Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Neonatal and Maternal Infections
- Blood disorders and treatments
- RNA regulation and disease
- Nerve Injury and Rehabilitation
Niigata University
2022-2023
Municipal Tsuruga Hospital
2022
Niigata University Medical and Dental Hospital
2022
University of California, San Diego
2019
Significance Platelets have an important role in blood clotting, but also function immune responses, including the release of antimicrobial peptides that eliminate pathogens such as Staphylococcus aureus . Here we observe group B Streptococcus (GBS), a leading cause sepsis and meningitis human newborns, is not killed by platelets. The key to GBS platelet resistance polysaccharide capsule coats bacterial surface contains sialic acid (Sia), common sugar present on all cells. Sia blocks...
A woman in her 30s underwent a 17-week ultrasound which revealed short bowed long bones. Fetal CT at 28 weeks’ gestation showed decreased ossification of the skull, small bell-shaped thorax, hypoplastic vertebrae, and shortening bowing bones, leading to diagnosis osteogenesis imperfecta (OI) type II. The newborn was delivered via caesarean delivery, tracheal intubation performed due respiratory distress. heterozygous variant COL1A1 (c.1679G>T, p. Gly358Val) ascertained, confirming OI...
A male junior high school student presented with failure to gain weight and acceleration of growth for 2 years. Free triiodothyronine free thyroxine levels were elevated, the thyroid-stimulating hormone (TSH) level was suppressed. TSH receptor antibody (TRAb) negative. On I-123 thyroid scintigraphy, iodine uptake most pronounced in upper pole right lobe. The patient initially diagnosed asymmetrical TRAb-negative Graves' disease (GD). His normalised potassium iodide (KI) alone, he became...