A5025883775- Intensive Care Unit Cognitive Disorders
- Anesthesia and Sedative Agents
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Sleep and related disorders
- Obstructive Sleep Apnea Research
- Genetic Neurodegenerative Diseases
- COVID-19 and healthcare impacts
- Neurological Disorders and Treatments
- Acute Ischemic Stroke Management
- Anesthesia and Neurotoxicity Research
- Dementia and Cognitive Impairment Research
- Neurological diseases and metabolism
- Neurological Disease Mechanisms and Treatments
- Dysphagia Assessment and Management
- Metalloenzymes and iron-sulfur proteins
- Metabolism and Genetic Disorders
- Cerebrovascular and genetic disorders
- Advanced Glycation End Products research
- Ion channel regulation and function
- EEG and Brain-Computer Interfaces
- Healthcare Decision-Making and Restraints
- Shoulder Injury and Treatment
- Infectious Encephalopathies and Encephalitis
Università Cattolica del Sacro Cuore
2020-2023
Agostino Gemelli University Polyclinic
2020-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2022
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
1991
Background and purpose The objective of this study was to assess the neurological manifestations in a series consecutive severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐positive patients, comparing their frequency with population hospitalized same period for flu/respiratory symptoms, finally not related SARS‐CoV‐2. Methods Patients symptoms admitted Fondazione Policlinico Gemelli hospital from 14 March 2020 20 April were retrospectively enrolled. patients SARS‐CoV‐2 infection...
Delirium is a neuropsychiatric disorder of attention and awareness that develops over short time fluctuates in severity. Although delirium has been extensively studied intensive care units, the incidence stroke units its predictors patients need further investigation. The endpoints our study were acute risk factors predispose to this condition.Patients consecutively enrolled unit from April October 2020. Inclusion criteria were: age ≥18 years, National Institute Health Stroke Scale (NIHSS)...
Objective: Neurological sequelae of SARS-CoV-2 infection have already been reported, but there is insufficient data about the impact pandemic on management patients with chronic neurological diseases. We aim to analyze effect COVID-19 and social restriction rules these fragile patients. Methods: Patients neurologic diseases routinely followed at outpatient clinic Gemelli University Hospital, Rome, were assessed for symptoms suggestive in period, consequences restrictions, disease features,...
Abstract Introduction Delirium is an acute fluctuating disorder of attention and awareness, which often complicates the clinical course several conditions, including stroke. The aim present study was to determine whether delirium occurrence impacts outcome patients with Methods design single center, prospective, observational. We consecutively enrolled admitted stroke unit from April October 2020. Inclusion criteria were age ≥ 18 years diagnosis Exclusion mimics, coma, terminal conditions....
The COVID-19 outbreak highly impacted the acute ischemic stroke care management. primary end point of study was to evaluate impact and following lockdown measures on our hub-and-spoke network; secondary if different in centers. This a retrospective multicenter observational conducted at Stroke Units Policlinico Gemelli, Ospedale San Filippo Neri, di Belcolle, Camillo de Lellis. We collected clinical reports all consecutive patients admitted with diagnosis or transient attack (TIA) during...
Background: There is a growing body of evidence suggesting link between obstructive sleep apnea (OSA) and atrial fibrillation (AF). The primary objective this study to evaluate the association OSA AF in acute ischemic stroke. secondary describe clinical features patients with stroke concomitant OSA. Methods: We enrolled consecutive All underwent full-night cardiorespiratory polygraphy. To determine if there an OSA, we compared observed frequency expected from random co-occurrence two...
Delirium is an acute fluctuating disorder of attention and awareness. It associated with autonomic dysfunction increased mortality. The primary endpoint our study was to measure activity in stroke patients, by means heart rate variability analysis, order identify modifications that can predispose delirium.
<b><i>Introduction:</i></b> Autonomic dysfunction has been reported as one of nonmotor manifestations both presymptomatic and manifest Huntington’s disease (HD). The aim our study was to evaluate heart rate variability (HRV) during wake sleep in a cohort patients with HD. <b><i>Methods:</i></b> Thirty consecutive HD were enrolled, 14 men 16 women, mean age 57.3 ± 12.2 years. All underwent full-night attended video polysomnography. HRV analyzed...
Pitolisant is a histamine 3-receptor antagonist/inverse agonist effective and safe for the treatment of excessive daytime sleepiness cataplexy in narcolepsy. We report 19-year-old woman affected by narcolepsy type 1 who presented panic attacks dissociative symptoms induced pitolisant. The patient medical history was unremarkable except that familiarity anxiety disorder chronic insomnia. Moreover, detailed psychometric evaluation revealed profile low resilience, severe grade depression, an...
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